Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bhargavi, Duvvuri"'
Autor:
Runa Kuley, Bhargavi Duvvuri, Jeffrey J. Wallin, Nam Bui, Mary Vic Adona, Nicholas G. O’Connor, Sharon K. Sahi, Ian B. Stanaway, Mark M. Wurfel, Eric D. Morrell, W. Conrad Liles, Pavan K. Bhatraju, Christian Lood
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTNeutrophil dysregulation is well established in COVID-19. However, factors contributing to neutrophil activation in COVID-19 are not clear. We assessed if N-formyl methionine (fMet) contributes to neutrophil activation in COVID-19. Elevated l
Externí odkaz:
https://doaj.org/article/68bb341cfe6c496ea2f3d2dd7b86a2b7
Autor:
Despina Michailidou, Bhargavi Duvvuri, Runa Kuley, David Cuthbertson, Peter C. Grayson, Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Carol A. McAlear, Larry W. Moreland, Christian Pagnoux, Philip Seo, Ulrich Specks, Antoine G. Sreih, Kenneth J. Warrington, Tomas Mustelin, Paul A. Monach, Peter A. Merkel, Christian Lood
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Objective To assess markers of neutrophil activation such as calprotectin and N-formyl methionine (fMET) in anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) and large-vessel vasculitis (LVV). Methods Levels of fMET, and c
Externí odkaz:
https://doaj.org/article/4d4ff93e6b7146b1804cbd57bf2f0bc4
Autor:
Runa Kuley, Ryan D. Stultz, Bhargavi Duvvuri, Ting Wang, Marvin J. Fritzler, Roger Hesselstrand, J Lee Nelson, Christian Lood
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Exaggerated neutrophil activation and formation of neutrophil extracellular traps (NETs) are reported in systemic sclerosis (SSc) but its involvement in SSc pathogenesis is not clear. In the present study we assessed markers of neutrophil activation
Externí odkaz:
https://doaj.org/article/3ce20637ff404c7d82326bcca62ebff7
Autor:
Bhargavi Duvvuri, Christian Lood
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Endogenous DNA is primarily found intracellularly in nuclei and mitochondria. However, extracellular, cell-free (cf) DNA, has been observed in several pathological conditions, including autoimmune diseases, prompting the interest of developing cfDNA
Externí odkaz:
https://doaj.org/article/2bcfd94e9b0e460b9f4a05edab0cb604
Autor:
Richard E. Moore, Ting Wang, Bhargavi Duvvuri, Marie L. Feser, Kevin D. Deane, Joshua J. Solomon, J. Lee Nelson, M. Kristen Demoruelle, Christian Lood
Publikováno v:
Arthritis & Rheumatology.
Autor:
Richard E, Moore, Ting, Wang, Bhargavi, Duvvuri, Marie L, Feser, Kevin D, Deane, Joshua J, Solomon, J Lee, Nelson, M Kristen, Demoruelle, Christian, Lood
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
Mitochondria are found in the extracellular space in rheumatoid arthritis (RA). However, whether mitochondria are a source of autoantigens in RA has not been carefully addressed. Thus, we investigated the presence and significance of anti-mitochondri
Autor:
Bhargavi Duvvuri, Lauren M. Pachman, Payton Hermanson, Ting Wang, Richard Moore, Dennis Ding-Hwa Wang, Aaron Long, Gabrielle A. Morgan, Stephen Doty, Rong Tian, Yasemin Sancak, Christian Lood
Publikováno v:
Journal of Autoimmunity. 138:103061
Publikováno v:
Nature reviews. Rheumatology. 18(11)
The mitochondrion is an intracellular organelle thought to originate from endosymbiosis between an ancestral eukaryotic cell and an α-proteobacterium. Mitochondria are the powerhouses of the cell, and can control several important processes within t
Autor:
Marisa Klein-Gitelman, Megan L. Curran, Gabrielle A. Morgan, Lauren M. Pachman, Amer Khojah, Christian Lood, Stephen B. Doty, Bhargavi Duvvuri
Publikováno v:
Arthritis & Rheumatology. 72:348-358
OBJECTIVE Neutrophils are key immune cells participating in host defense through several mechanisms, including the formation of neutrophil extracellular traps (NETs). This study was undertaken to investigate the role of neutrophils in juvenile dermat
Autor:
Susan L. Fink, Michael Gale, Olga Yakovenko, Michael Davis, Andreas B. den Hartigh, Christian Lood, Wendy E. Thomas, Marian R. Fairgrieve, Bhargavi Duvvuri
Publikováno v:
Proceedings of the National Academy of Sciences. 116:5061-5070
Pyroptosis is an inflammatory form of programmed cell death following cellular damage or infection. It is a lytic process driven by gasdermin D-mediated cellular permeabilization and presumed osmotic forces thought to induce swelling and rupture. We