Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation

Autor: Jesper V. Olsen, Atul S. Deshmukh, Patrick Rüther, Alba Gonzalez-Franquesa, Maxim A. X. Tollenaere, Simon Bekker-Jensen, Tanveer S. Batth, Bhargav S. Prabhakar

Publikováno v: Batth, T S, Tollenaere, M A X, Rüther, P L, Gonzalez-Franquesa, A, Prabhakar, B S, Bekker-Jensen, S H, Deshmukh, A S & Olsen, J V 2019, ' Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation ', Molecular and Cellular Proteomics, vol. 18, no. 5, pp. 1027-1035 . https://doi.org/10.1074/mcp.TIR118.001270
Molecular & Cellular Proteomics

Universal proteomics sample preparation is challenging due to the high heterogeneity of biological samples. Here we describe a novel mechanism that exploits the inherent instability of denatured proteins for non-specific immobilization on micropartic

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https://curis.ku.dk/portal/da/publications/protein-aggregation-capture-on-microparticles-enables-multipurpose-proteomics-sample-preparation(a81d6964-f019-4b44-a488-295153e260f8).html