Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bhargav Kondeti"'
Autor:
Mayank Aggarwal, Bhargav Kondeti, Chingkuang Tu, C. Mark Maupin, David N. Silverman, Robert McKenna
Publikováno v:
IUCrJ, Vol 1, Iss 2, Pp 129-135 (2014)
Human carbonic anhydrases (CAs) are zinc metalloenzymes that catalyze the hydration and dehydration of CO2 and HCO3−, respectively. The reaction follows a ping-pong mechanism, in which the rate-limiting step is the transfer of a proton from the zin
Externí odkaz:
https://doaj.org/article/0a64531c38bd4bdc8d942f785621a203
Autor:
C.M. Maupin, Bhargav Kondeti, Chingkuang Tu, Mayank Aggarwal, David N. Silverman, Robert McKenna
Publikováno v:
IUCrJ, Vol 1, Iss 2, Pp 129-135 (2014)
Iucrj
Iucrj
Human carbonic anhydrases are zinc metalloenzymes that catalyze the hydration and dehydration of CO2 and HCO3 −, respectively. X-ray crystal structures of a variant of human carbonic anhydrase II in complex with four imidazole derivatives (imidazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e99be86ec8c183983a76ba8f8b9e7e
https://doi.org/10.1107/s2052252514004096
https://doi.org/10.1107/s2052252514004096
Publikováno v:
Expert Opinion on Therapeutic Patents. 23:717-724
An epileptic seizure is a transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain. The International League Against Epilepsy classifies seizures in two broad categories: partial (localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9fc2153fef57375fdab83e6e26234b
https://doi.org/10.1517/13543776.2013.782394
https://doi.org/10.1517/13543776.2013.782394
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 28:267-277
Carbonic anhydrases (CAs, EC 4.2.1.1) are a family of metalloenzymes that catalyze the reversible interconversion of CO(2) and HCO(3)(-). Of the 15 isoforms of human (h) α-CA, 12 are catalytic (hCAs I-IV, VA, VB, VI, VII, IX, XII-XIV). The remaining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cc609e07fa06521fff285337080f77
https://doi.org/10.3109/14756366.2012.737323
https://doi.org/10.3109/14756366.2012.737323
Autor:
Bhargav Kondeti, Chingkuang Tu, Mayank Aggarwal, David N. Silverman, Christopher D. Boone, Robert McKenna
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 69(Pt 5)
Protein X-ray crystallography has seen a progressive shift from data collection at cool/room temperature (277–298 K) to data collection at cryotemperature (100 K) because of its ease of crystal preparation and the lessening of the detrimental effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777481a85d9506a2edbd8ddeefa0fddb
https://pubmed.ncbi.nlm.nih.gov/23633596
https://pubmed.ncbi.nlm.nih.gov/23633596
Publikováno v:
Bioorganicmedicinal chemistry. 21(6)
Carbonic anhydrases (CAs, EC 4.2.1.1) are a group of metalloenzymes that play important roles in carbon metabolism, pH regulation, CO2 fixation in plants, ion transport etc., and are found in all eukaryotic and many microbial organisms. This family o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcae8a1891cf3a5d4cda32201785001e
https://pubmed.ncbi.nlm.nih.gov/22985956
https://pubmed.ncbi.nlm.nih.gov/22985956