Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bharati Hukku"'
Autor:
Jill A. Macoska, Johng S. Rhim, Ben Beheshti, Jeff E. Lehr, Jeremy A. Squire, Kenneth J. Pienta, Bharati Hukku
Publikováno v:
Cancer Genetics and Cytogenetics. 120:50-57
We have utilized a combination of conventional and spectral karyotyping (SKY) techniques and allelotype analysis to assess numerical and structural chromosome alterations in two cell lines derived from normal human prostatic epithelium, and three cel
Publikováno v:
Cancer Genetics and Cytogenetics. 120:117-126
Cytogenetics, fluorescence in situ hybridization (FISH), and comparative genomic hybridization (CGH) were used to identify genes that are involved in the development and progression of prostate cancer. For that purpose, we chose a cell line establish
Publikováno v:
Biochemical Pharmacology. 55:1135-1138
The molecular bases for the 6-fold elevated methotrexate transport capacity of K562.4CF cells (Matherly et al., Cancer Res. 51: 3420-3426, 1991) were studied with reduced folate carrier (RFC) cDNA, genomic, and antibody probes. Southern analysis show
Publikováno v:
Carcinogenesis. 18:1251-1257
To establish a cell culture model for lung carcinogenesis, independent populations of the human papillomavirus 18-immortalized human bronchial epithelial cell line BEP2D were treated with high linear energy transfer radon-simulated alpha-particles, e
Publikováno v:
Cancer Genetics and Cytogenetics. 93:125-139
Human epithelial cancer cells were induced by concerted action of DNA tumor virus and X-ray radiation. Treatment of nontumorigenic early passage AD12-SV40 immortalized epithelial cells (RHEK-1) at passage 23 with radiation, resulted in further change
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 32:656-662
Methods for monitoring cell line identification and authentication include species-specific immunofluorescence, isoenzyme phenotyping, chromosome analysis, and DNA fingerprinting. Most previous studies of DNA fingerprinting of cell lines have used re
Autor:
Elsa L. Moy, S. G. Warneford, K. Maclean, Bharati Hukku, Roger R. Reddel, Andy C.-M. Chang, Anna Englezou, E. M. Rogan, Tracy M. Bryan, Luciano Dalla-Pozza
Publikováno v:
Molecular and Cellular Biology. 15:4745-4753
Normal cells have a strictly limited growth potential and senesce after a defined number of population doublings (PDs). In contrast, tumor cells often exhibit an apparently unlimited proliferative potential and are termed immortalized. Although spont
Publikováno v:
Neurology. 59:780-782
Sturge–Weber syndrome (SWS) is a neurocutaneous syndrome characterized by port wine staining in the skin of the face and leptomeningeal angiomatosis, usually in the occipital or parieto-occipital regions.1 It has been proposed that neurocutaneous d
Autor:
Marc J. Mass, Brenda I. Gerwin, Gary D. Stoner, Anthony J. Galati, Simone E. Salghetti, Ih-Chang Hsu, Roger R. Reddel, Angela N. A. Somers, William T. Gunning, Curtis C. Harris, Bharati Hukku
Publikováno v:
International Journal of Cancer. 48:764-773
Bronchial epithelial cells were cultured from an individual with no evidence of malignant disease. These cells, designated HB56B, had a greatly extended in vitro life-span, being able to undergo 50 passages and 200 population doublings in contrast to
Autor:
Yongpeng Gu, David G. McLeod, Bharati Hukku, Tom K. Hei, Hongzhen Li, Johng S. Rhim, Jun Miki
Publikováno v:
International Journal of Oncology.
Although epidemiological studies have suggested a positive correlation between environmental radon exposure and prostate cancer, the mechanism involved is not clear. In the present study, we examined the oncogenic transforming potency of alpha-partic