Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bharath H. Rathnakar"'
Autor:
Lorin E. Olson, Constantin Georgescu, Bharath H. Rathnakar, Shayna C. Medley, Jonathan D. Wren
Publikováno v:
Wound Repair Regen
Signal transducer and activator of transcription 1 (Stat1) is a ubiquitously expressed latent transcription factor that is activated by many cytokines and growth factors. Global Stat1 knockout mice are prone to chemical-induced lung and liver fibrosi
Autor:
Longbiao Yao, Bharath H. Rathnakar, Hae Ryong Kwon, Hiromi Sakashita, Jang H. Kim, Alex Rackley, James J. Tomasek, William L. Berry, Lorin E. Olson
Publikováno v:
Cell reports. 40(7)
Fibroblasts differentiate into myofibroblasts by acquiring new contractile function. This is important for tissue repair, but it also contributes to organ fibrosis. Platelet-derived growth factor (PDGF) promotes tissue repair and fibrosis, but the re
Autor:
Bharath H. Rathnakar, James J. Tomasek, Jang Kim, Lorin E. Olson, William L. Berry, Hiromi Sakashita, Longbiao Yao
Publikováno v:
SSRN Electronic Journal.
The appearance of myofibroblasts is hallmark of fibrosis and tissue repair. Myofibroblasts are stromal cells that transition from fibroblastic progenitors by acquiring new contractile function. Platelet-derived growth factor (PDGF) promotes fibrosis