Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bharat Ravindra Zope"'
Autor:
Sven Ruf, Sridharan Rajagopal, Sanjay Venkatachalapathi Kadnur, Mahanandeesha S. Hallur, Shilpa Rani, Rajendra Kristam, Srinivasan Swaminathan, Bharat Ravindra Zope, Pavan Kumar Gondrala, Indu Swamy, V. P. Rama Kishore Putta, Saravanan Kandan, Gernot Zech, Herman Schreuder, Christine Rudolph, Ralf Elvert, Joerg Czech, Swarnakumari Birudukota, M. Amir Siddiqui, Niranjan Naranapura Anand, Vishal Subhash Mane, Sreekanth Dittakavi, Juluri Suresh, Ramachandraiah Gosu, Mullangi Ramesh, Takeshi Yura, Saravanakumar Dhakshinamoorthy, Aimo Kannt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Nicotinamide N-methyltransferase (NNMT) is a metabolic regulator that catalyzes the methylation of nicotinamide (Nam) using the co-factor S-adenosyl-L-methionine to form 1-methyl-nicotinamide (MNA). Overexpression of NNMT and the presence of
Externí odkaz:
https://doaj.org/article/1bd53e86e70b4c66b07f2146adca9f2e
Autor:
K.V. Sanjay, Santosh Vishwakarma, Bharat Ravindra Zope, Vishal Subhash Mane, Sunil Mohire, Saravanakumar Dhakshinamoorthy
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss , Pp 100051- (2021)
Non-alcoholic fatty liver disease (NAFLD) and Non-alcoholic steatohepatitis (NASH) are chronic liver disorders, the prevalence of which is increasing worldwide. Long term High Fat Diet (HFD) induced NASH animal models closely mimic the characteristic
Externí odkaz:
https://doaj.org/article/95312270df7b44bebff577340ea88910
Autor:
Srinivasan Swaminathan, Rajendra Kristam, Manish Kumar Thakur, Anja Pfenninger, Vishal Subhash Mane, Saravanakumar Dhakshinamoorthy, Ralf Elvert, Saravanan Kandan, Niranjan Naranapura Anand, Takeshi Yura, Reejuana Parveen, Ravi Kanth Bhamidipati, Devaraj Venkatapura Chandrasekar, Ramesh Mullangi, Sridharan Rajagopal, Raghunadha Reddy Burri, Herman Schreuder, Mahanandeesha S. Hallur, Sven Ruf, Manvi Singh, Jörg Czech, Juluri Suresh, Ramachandraiah Gosu, Shama Shaik, Sanjay Venkatachalapathi Kadnur, Swarnakumari Birudukota, Bharat Ravindra Zope, Aimo Kannt, Christine Rudolph
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Nicotinamide N-methyltransferase (NNMT) is a cytosolic enzyme that catalyzes the transfer of a methyl group from the co-factor S-adenosyl-L-methionine (SAM) onto the substrate, nicotinamide (NA) to form 1-methyl-nicotinamide (MNA). Higher NNMT expres
Autor:
Saravanakumar Dhakshinamoorthy, Dhanalakshmi Sivanandhan, Amir Siddiqui, Zaheerbasha Sameermahmood, Srinivasan Swaminathan, V. Krishnakumar, D.A Jeyaraj, Biswajit Kalita, Rudresh G, Madhuri Kanavalli, Sowmya Ramaiah, Raghunadha Reddy Burri, Sanjay Venkatachalapathi Kadnur, Rajendra Kristam, Sriram Rajagopal, Bharat Ravindra Zope, Sunil Mohire
Publikováno v:
Diabetes. 68
Impaired insulin secretion, a characteristic of type 2 diabetes (T2D) is partly attributed to decreased β-cell mass due to apoptotic cell death under diabetogenic conditions. Current therapies for diabetes do not address apoptotic cell death mediate