Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bharat Kumar Reddy Chaganty"'
Autor:
Gabriel Lopez-Berestein, Songbo Qiu, Bulent Ozpolat, Zhen Fan, Yang Lu, Bharat Kumar Reddy Chaganty
Publikováno v:
Cancer Immunology, Immunotherapy
We tested the concept that host preexisting influenza A virus immunity can be redirected to inhibit tumor growth and metastasis through systemic administration of influenza A virus-related peptides to targeted tumors. Mice infected with influenza A v
Autor:
Xudong Wang, Zhen Fan, Yun Hong, Songbo Qiu, Qiang Li, Yang Lu, Lun Zhang, Bharat Kumar Reddy Chaganty, Jingtao Luo
Publikováno v:
Cancer Letters. 384:39-49
Cetuximab inhibits HIF-1-regulated glycolysis in cancer cells, thereby reversing the Warburg effect and leading to inhibition of cancer cell metabolism. AMP-activated protein kinase (AMPK) is activated after cetuximab treatment, and a sustained AMPK
Autor:
Ashlesh K. Murthy, Margarita M. Vasquez, Steven R. Seidner, Guangming Zhong, M. Neal Guentzel, Dale M. Selby, Barbara M. Henson, Shamimunisa B. Mustafa, Bharat Kumar Reddy Chaganty, Madhulika Jupelli, Bernard P. Arulanandam
Publikováno v:
Laboratory Investigation. 91:1530-1539
Respiratory dysfunction in adults has been correlated with neonatal Chlamydia trachomatis pneumonia in several studies, but a causal association has not been clearly demonstrated. In this study, we examined radial alveolar counts (RACs) by microscopy
Autor:
Thomas G. Forsthuber, Guangming Zhong, Bernard P. Arulanandam, Weidang Li, M. Neal Guentzel, Ashlesh K. Murthy, Sangamithra Kamalakaran, Janakiram Seshu, Bharat Kumar Reddy Chaganty
Publikováno v:
Infection and Immunity. 79:2928-2935
The immunopathogenesis of Chlamydia trachomatis -induced oviduct pathological sequelae is not well understood. Mice genetically deficient in perforin (perforin −/− mice) or tumor necrosis factor alpha (TNF-α) production (TNF-α −/− mice) dis
Autor:
Guangming Zhong, Janakiram Seshu, Bharat Kumar Reddy Chaganty, Bernard P. Arulanandam, James P. Chambers, Weidang Li, M. Neal Guentzel, Ashlesh K. Murthy
Publikováno v:
FEMS Immunology & Medical Microbiology. 55:271-279
Mice deficient in B cells (micromT mice) were used to evaluate the role of antibody in enhanced chlamydial clearance and reduction of pathology afforded by vaccination with recombinant chlamydial protease-like activity factor (rCPAF). Enhanced, but c
Autor:
Ashlesh K. Murthy, Shankar J. Evani, Anand K. Ramasubramanian, Mark T. Zafiratos, Srikanth Manam, Bernard P. Arulanandam, Bharat Kumar Reddy Chaganty
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64917 (2013)
PLoS ONE
PLoS ONE
Chlamydia trachomatis is the most common bacterial sexually transmitted disease in the world and specifically in the United States, with the highest incidence in age-groups 14-19 years. In a subset of females, the C. trachomatis genital infection lea
Autor:
M. Neal Guentzel, Ashlesh K. Murthy, Janakiram Seshu, Bharat Kumar Reddy Chaganty, Weidang Li, Bernard P. Arulanandam, James P. Chambers, Guangming Zhong
Publikováno v:
Frontiers in Immunology, Vol 2 (2011)
Frontiers in Immunology
Frontiers in Immunology
We have shown that immunization with soluble recombinant chlamydial protease-like activity factor (rCPAF) and a T helper 1 type adjuvant can induce significantly enhanced bacterial clearance and protection against Chlamydia-induced pathological seque
Autor:
Bernard P. Arulanandam, Weidang Li, M. Neal Guentzel, Guangming Zhong, Shankar J. Evani, James P. Chambers, Ashlesh K. Murthy, Bharat Kumar Reddy Chaganty
Publikováno v:
Vaccine. 28(11)
We have shown previously that vaccination with recombinant chlamydial protease-like activity factor (rCPAF) plus interleukin-12 as an adjuvant induces robust protective immunity against primary genital Chlamydia muridarum challenge in mice. Since CPA
Autor:
Dean A. Lee, Bharat Kumar Reddy Chaganty, Srinivas S. Somanchi, Yang Lu, Zhen Fan, Songbo Qiu
Publikováno v:
OncoImmunology. 5:e1100790
It is increasingly recognized that trastuzumab, an antibody approved for treating human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer, exerts some of its antitumor effects through enhanced T cell responses. Full activation of