Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bharat Jagannathan"'
Autor:
Diandra Martinez-Cano, Rashmi Ravichandran, Huong Le, H. Edward Wong, Bharat Jagannathan, Erik J. Liu, William Bailey, Jane Yang, Kelli Matthies, Hedieh Barkhordarian, Bhavana Shah, Nithya Srinivasan, Jun Zhang, Angel Hsu, Jette Wypych, Jennitte Stevens, Deirdre Murphy Piedmonte, Les P. Miranda, Lauren Carter, Michael Murphy, Neil P. King, Neil Soice
Publikováno v:
Process Biochemistry. 129:241-256
Autor:
Annette Medina Morales, Alavattam Sreedhara, Jakob Buecheler, Sebastian Brosig, Danny Chou, Twinkle Christian, Tapan Das, Isabella de Jong, Jonas Fast, Bharat Jagannathan, Ehab M. Moussa, M. Reza Nejadnik, Indira Prajapati, Allison Radwick, Yusra Rahman, Shubhadra Singh
Publikováno v:
The AAPS journal. 25(1)
A survey performed by the AAPS Drug Product Handling community revealed a general, mostly consensus, approach to the strategy for the selection of surfactant type and level for biopharmaceutical products. Discussing and building on the survey results
Autor:
Linda O. Narhi, Danny K. Chou, Twinkle. R. Christian, Scott Gibson, Bharat Jagannathan, Wim Jiskoot, Susan Jordan, Alavattam Sreedhara, Lloyd Waxman, Tapan K. Das
Publikováno v:
Journal of Pharmaceutical Sciences, 111(4), 887-902
Protein-based biologic drugs encounter a variety of stress factors during drug substance (DS) and drug product (DP) manufacturing, and the subsequent steps that result in clinical administration by the end user. This article is the third in a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d52500cdb925a4592e909fd39c998f
https://hdl.handle.net/1887/3281078
https://hdl.handle.net/1887/3281078
Autor:
Frankie Petoskey, Lori S. Burton, Sonal Saluja, Barbara Kühnle, Twinkle R. Christian, Rameez Kagdi, Camellia Zamiri, Ganapathy Gopalrathnam, Sarah Elizabeth Weiser, Alpa Bhattacharyya, Bharat Jagannathan, Kathy Hanley
Publikováno v:
Journal of pharmaceutical sciences. 110(6)
Closed system transfer devices (CSTDs) have been used with hazardous drugs for several decades. The goal of this whitepaper is to increase awareness among healthcare professionals, device manufacturers, regulators, and pharmaceutical/biotech companie
Autor:
Michael Cram, Camellia Zamiri, Alavattam Sreedhara, Sarah Elizabeth Weiser, Sumit Goswami, Twinkle R. Christian, Bharat Jagannathan
Publikováno v:
Journal of pharmaceutical sciences. 109(1)
Hazardous drug is a common term used by the National Institute of Occupational Health and Safety (NIOSH) to classify medications that may induce adverse mutagenic and reproductive responses in health care personnel. NIOSH publishes a list of drugs it
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1857:548-556
Site-directed spin labeling electron paramagnetic resonance (SDSL EPR) spectroscopy is a powerful tool to determine solvent accessibility, side-chain dynamics, and inter-spin distances at specific sites in biological macromolecules. This information
Autor:
Susan Marqusee, Bharat Jagannathan
Publikováno v:
Biopolymers. 99:860-869
The recent revolution in optics and instrumentation has enabled the study of protein folding using extremely low mechanical forces as the denaturant. This exciting development has led to the observation of the protein folding process at single molecu
Publikováno v:
Biophysical Journal. 110(3)
A fundamental question in protein folding is whether proteins fold through one or multiple trajectories. Although most protein folding experiments indicate a single pathway, we have demonstrated the presence of multiple unfolding pathways in a simple
Autor:
Bharat Jagannathan, John H. Golbeck
Publikováno v:
Cellular and Molecular Life Sciences. 66:1257-1270
The elucidation of assembly pathways of multi-subunit membrane proteins is of growing interest in structural biology. In this study, we provide an analysis of the assembly of the asymmetrically oriented PsaC subunit on the pseudo C(2)-symmetric Photo
Autor:
Bharat Jagannathan, John H. Golbeck
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777(12):1535-1544
The photosynthetic reaction center from the green sulfur bacterium Chlorobium tepidum (CbRC) was solubilized from membranes using Triton X-100 and isolated by sucrose density ultra-centrifugation. The CbRC complexes were subsequently treated with 0.5