Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bharat, Khade"'
Autor:
Abhiram Natu, Tripti Verma, Bharat Khade, Rahul Thorat, Poonam Gera, Sangita Dhara, Sanjay Gupta
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Cisplatin is an alkylating class of chemotherapeutic drugs used to treat cancer patients. However, cisplatin fails in long-term treatment, and drug resistance is the primary reason for tumor recurrence. Hence, understanding the mechanism of
Externí odkaz:
https://doaj.org/article/fe1f6723af554c7eb2b4dd6e8d53ee73
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-11 (2017)
Abstract Background Dysregulation in post-translational modifications of histones and their modifiers are now well-recognized as a hallmark of cancer and can be used as biomarkers and potential therapeutic targets for disease progression and prognosi
Externí odkaz:
https://doaj.org/article/7cd5453cec284bbeb89d6d9b7745f948
Publikováno v:
Experimental Biology and Medicine. :153537022311603
Replication-dependent histones have a stem-loop structure at the 3′ end of messenger RNA (mRNA) and are stabilized by stem-loop binding protein (SLBP). Moreover, loss of SLBP and imbalance in the level of ARE (adenylate-uridylate-rich elements)-bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ad5061b95ba896974ef4010b0a6231b
https://doi.org/10.1177/15353702231160328
https://doi.org/10.1177/15353702231160328
Autor:
Bharat Khade, Rahul Thorat, Ramchandra Vigay Amnekar, Sanjay Gupta, Duane T. Smoot, Shafqat Ali Khan, Mudasir Rashid, Hassan Ashktorab, Poonam Gera, Shailesh V. Shrikhande
Publikováno v:
World Journal of Gastroenterology
BACKGROUND The prognosis of gastric cancer continues to remain poor, and epigenetic drugs like histone deacetylase inhibitors (HDACi) have been envisaged as potential therapeutic agents. Nevertheless, clinical trials are facing issues with toxicity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c491b96615ac197903697898fa6ae0ec
http://europepmc.org/articles/PMC7029347
http://europepmc.org/articles/PMC7029347
Autor:
Tripti Verma, Poonam Gera, Bharat Khade, Mudasir Rashid, Madan Ludbe, Sanket Shah, Sanjay Gupta
Publikováno v:
Cell and Tissue Banking. 20:489-499
Biomarkers are biological characteristic to measure and evaluate normal and pathological states. To define expression-based molecular biomarkers, high-quality tissue samples are a prerequisite for the preparation of standard RNA. It is already known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652c06e7cdc60c65507b0ae55ed219f2
https://doi.org/10.1007/s10561-019-09782-7
https://doi.org/10.1007/s10561-019-09782-7
Autor:
Radhika Poojari, Bhabani Mohanty, Vijay Kadwad, Dayaram Suryawanshi, Pradip Chaudhari, Bharat Khade, Rohit Srivastava, Sanjay Gupta, Dulal Panda
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 41
Hepatocellular carcinoma (HCC) is the most aggressive form of cancer with poor drug responses. Developing an effective drug treatment remains a major unmet clinical need for HCC. We report a comprehensive study of combinatorial Cetuximab (Cet) target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3778ceb5b82f1bf97cc0c07f92ff3166
https://pubmed.ncbi.nlm.nih.gov/35104671
https://pubmed.ncbi.nlm.nih.gov/35104671
Autor:
Sanket G, Shah, Mudasir, Rashid, Tripti, Verma, Madan, Ludbe, Bharat, Khade, Poonam B, Gera, Sanjay, Gupta
Publikováno v:
Cell and tissue banking. 20(4)
Biomarkers are biological characteristic to measure and evaluate normal and pathological states. To define expression-based molecular biomarkers, high-quality tissue samples are a prerequisite for the preparation of standard RNA. It is already known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b03837e55fd2a0a7e32258b2e81a3d73
https://pubmed.ncbi.nlm.nih.gov/31444592
https://pubmed.ncbi.nlm.nih.gov/31444592
Publikováno v:
Anti-cancer agents in medicinal chemistry. 18(13)
Background: At present, ‘pharmaco-epigenomics’ constitutes the hope in cancer treatment owing to epigenetic deregulation- a reversible process and playing a role in malignancy. Objective: Chemotherapy has many limitations like host-tissue toxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8488e64b59a7ca47c28a569826493b96
https://pubmed.ncbi.nlm.nih.gov/29623853
https://pubmed.ncbi.nlm.nih.gov/29623853
Publikováno v:
Experimental Biology and Medicine. 239:1335-1339
Recent studies suggest the incorporation of histone variants into the chromatin regulate cellular proliferation, differentiation, and de-differentiation. We have earlier reported the increase of H2A.1 variant during sequential de-differentiation of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449dbda5c86b2e5d45edfe8a92cc7449
https://doi.org/10.1177/1535370214531869
https://doi.org/10.1177/1535370214531869
Autor:
Shafqat Ali Khan, Shailesh V. Shrikhande, Mukta Ramadwar, Savio G. Barreto, Sanjay Gupta, Bharat Khade, Ramchandra Vigay Amnekar
Publikováno v:
Clinical Epigenetics
Background Alterations in histone modifications are now well known to result in epigenetic heterogeneity in tumor tissues; however, their prognostic value and association with resection margins still remain poorly understood and controversial. Furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8883fec80e68f5d561908f85f7df6b9f
https://doi.org/10.1186/s13148-016-0255-9
https://doi.org/10.1186/s13148-016-0255-9