Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Bhanudas Gaikwad, A."'
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Acute kidney injury (AKI)‐to‐chronic kidney disease (CKD) transition involves a complex pathomechanism, including inflammation, apoptosis, and fibrosis where long non‐coding RNAs (lncRNAs) play a crucial role in their regulation. Howev
Externí odkaz:
https://doaj.org/article/e04f618bc6f64cadb96258173abc49d6
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid), Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus Disease (COVID)-19. Although chronic kidney disease is a highly prevalent
Externí odkaz:
https://doaj.org/article/263ec1b938684aa58e5770dfa5228be5
Publikováno v:
In Drug Discovery Today August 2021 26(8):1963-1971
Publikováno v:
Cells, Vol 12, Iss 20, p 2440 (2023)
Calcineurin inhibitors (CNI) can suppress allo- and autoimmunity by suppressing T cell function but also have anti-proteinuric effects by stabilizing the cellular components of the kidney’s filtration barrier. Therefore, CNI are used in autoimmune
Externí odkaz:
https://doaj.org/article/3217f31635ca41c3ab86ba80592dae7d
Autor:
Almesh Kadakol, Vajir Malek, Santosh Kumar Goru, Anuradha Pandey, Nisha Sharma, Anil Bhanudas Gaikwad
Publikováno v:
Journal of Functional Foods, Vol 35, Iss , Pp 256-266 (2017)
Insulin resistance (IR) and type 2 diabetic nephropathy (T2DN) are associated with elevated renal expression of monocyte chemo-attractant protein (MCP1) and transforming growth factor-β (TGF-β). Posttranslational histone modifications (PTHMs) play
Externí odkaz:
https://doaj.org/article/ecce4dea3a764ebfa97f1b617e542a84
Publikováno v:
Archives of Physiology and Biochemistry. :1-9
Persistent hyperglycaemia increases SET7/9 expression and endoplasmic reticulum (ER) stress which causes inflammation, apoptosis, and fibrosis in renal tubular epithelial cells leading to diabetic kidney disease (DKD).Current study explores the renop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ac8c7b73671ff59e65fe886242656f
https://doi.org/10.1080/13813455.2022.2105365
https://doi.org/10.1080/13813455.2022.2105365
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:234-239
Persistent hyperglycemia in type 1 diabetes triggers numerous signaling pathways, which may prove deleterious to the endothelium. As hyperglycemia damages the endothelial layer via multiple signaling pathways, including enhanced oxidative stress, dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d46dd4e52a989ded6077c5ec7af7295
https://doi.org/10.1139/cjpp-2021-0170
https://doi.org/10.1139/cjpp-2021-0170
Publikováno v:
BioDrugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67cefa77acb97e8246f025312f395efb
https://doi.org/10.1007/s40259-023-00597-3
https://doi.org/10.1007/s40259-023-00597-3
Publikováno v:
Nephrology Dialysis Transplantation. 38:819-825
Klotho is a transmembrane anti-ageing protein that exists in three forms, i.e. α-Klotho, β-Klotho and γ-Klotho, with distinct organ-specific expression and functions in the body. Here we focus on α-Klotho (hereafter Klotho), abundantly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6669c34739e153e03842789e176f0e5
https://doi.org/10.1093/ndt/gfab340
https://doi.org/10.1093/ndt/gfab340
Publikováno v:
Food & Function.
Toll-like receptor 4 (TLR4) and sodium-glucose co-transporter 2 (SGLT2) signaling is involved in the pathogenesis of diabetes-associated kidney diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::194f0794cb3cf90428bc089b8063cc80
https://doi.org/10.1039/d3fo01379k
https://doi.org/10.1039/d3fo01379k