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pro vyhledávání: '"Bhanu Sadasivan"'
Autor:
Jack R. Bennink, Peter Cresswell, Shiv A. Prasad, Jonathan W. Yewdell, Bhanu Sadasivan, Angel Porgador
Publikováno v:
European Journal of Immunology. 28:907-913
We investigated the requirement for calnexin in the biogenesis of MHC class I molecules. Mutant human cells lacking calnexin were infected with recombinant vaccinia viruses encoding mouse MHC class I molecules, K d , Kb , Kk , D d , Db , and Ld . Flo
Autor:
Peter Cresswell, Robert Tampé, Bodo Ortmann, Stanley R. Riddell, John Trowsdale, Andeas G. Grandea, Paul J. Lehner, Thomas Spies, James Copeman, Bhanu Sadasivan, Jethro Herberg
Publikováno v:
Science (New York, N.Y.). 277(5330)
Newly assembled major histocompatibility complex (MHC) class I molecules, together with the endoplasmic reticulum chaperone calreticulin, interact with the transporter associated with antigen processing (TAP) through a molecule called tapasin. The mo
Publikováno v:
Immunity. 5(2)
Assembly of MHC class I–β 2 microglobulin (β 2 m) dimers in the endoplasmic reticulum involves two chaperones. Calnexin has previously been shown to interact with free class I heavy chains. Here, we show that the related chaperone, calreticulin,