Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Bhanu Kanth Manne"'
Autor:
Li Guo, Shancy Jacob, Bhanu Kanth Manne, E. Motunrayo Kolawole, Siqi Guo, Xiang Wang, Darian Murray, Emilia A. Tugolukova, Irina Portier, Yasuhiro Kosaka, Cindy Barba, Matthew T. Rondina, Brian Evavold, Celeste Morley, Seema Bhatlekar, Paul F. Bray
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/14029ee60bef4e05b8286f1d78fd4155
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100176- (2023)
Externí odkaz:
https://doaj.org/article/d837f4397d92467fbc2574597b485044
Autor:
Robert A. Campbell, Bhanu Kanth Manne, Meenakshi Banerjee, Elizabeth A. Middleton, Abigail Ajanel, Hansjorg Schwertz, Frederik Denorme, Chris Stubben, Emilie Montenont, Samantha Saperstein, Lauren Page, Neal D. Tolley, Diana L. Lim, Samuel M. Brown, Colin K. Grissom, Douglas W. Sborov, Anandi Krishnan, Matthew T. Rondina
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Platelets and megakaryocytes are critical players in immune responses. Recent reports suggest infection and inflammation alter the megakaryocyte and platelet transcriptome to induce altered platelet reactivity. We determined whether nonviral sepsis i
Externí odkaz:
https://doaj.org/article/e7cbbd51329f4220a8154731cd4de615
Autor:
Kimberly A. Queisser, Rebecca A. Mellema, Elizabeth A. Middleton, Irina Portier, Bhanu Kanth Manne, Frederik Denorme, Ellen J. Beswick, Matthew T. Rondina, Robert A. Campbell, Aaron C. Petrey
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Vascular injury has emerged as a complication contributing to morbidity in coronavirus disease 2019 (COVID-19). The glycosaminoglycan hyaluronan (HA) is a major component of the glycocalyx, a protective layer of glycoconjugates that lines the vascula
Externí odkaz:
https://doaj.org/article/798bcc9a321f4bae81e1bef6a76e3e62
Autor:
Matthew Thomas Rondina, Robert A. Campbell, Anish Bhatnagar, Zechariah Franks, Jesse W. Rowley, Bhanu Kanth Manne, Mark A. Supiano, Alistair N. Ward
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 56-56 (2017)
OBJECTIVES/SPECIFIC AIMS: Platelets govern signal-dependent inflammatory responses by leukocytes. Although dysregulated inflammation is common in older adults, platelet-leukocyte signaling events and downstream inflammatory gene synthesis in aging is
Externí odkaz:
https://doaj.org/article/648562199656416dba167f1b283a92e0
Autor:
Bhanu Kanth Manne, Robert A. Campbell, Seema Bhatlekar, Abigail Ajanel, Frederik Denorme, Irina Portier, Elizabeth A. Middleton, Neal D. Tolley, Yasuhiro Kosaka, Emilie Montenont, Li Guo, Jesse W. Rowley, Paul F. Bray, Shancy Jacob, Rikiro Fukanaga, Christopher Proud, Andrew S. Weyrich, Matthew T. Rondina
Publikováno v:
Blood. 140:2477-2489
The MAPK-interacting kinase (Mnk) family includes Mnk1 and Mnk2, which are phosphorylated and activated in response to extracellular stimuli. Mnk1 contributes to cellular responses by regulating messenger RNA (mRNA) translation, and mRNA translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab09cc09f6d910c7c6de0ae3d3abb9c9
https://doi.org/10.1182/blood.2022015568
https://doi.org/10.1182/blood.2022015568
Autor:
Marcus V. G. Lacerda, Eugenio D. Hottz, Bhanu Kanth Manne, Andrew S. Weyrich, Hugo Castro Faria Neto, Guy A. Zimmerman, Krystin Krauel, Emilie Montenont, Antoinette Blair, Neal D. Tolley, Isabel M. Medeiros-de-Moraes, Jesse W. Rowley, Matthew T. Rondina, Aaron C. Petrey, Elizabeth A. Middleton, Robert A. Campbell, Alicia S Eustes, Yasuhiro Kosaka, Li Guo
Publikováno v:
J Thromb Haemost
Background Heparanase (HPSE) is the only known mammalian enzyme that can degrade heparan sulfate. Heparan sulfate proteoglycans are essential components of the glycocalyx, and maintain physiological barriers between the blood and endothelial cells. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e53ee284a575380aa2c8d3ce3e6005
https://doi.org/10.1111/jth.15266
https://doi.org/10.1111/jth.15266
Autor:
Li Guo, Seema Bhatlekar, Shancy P Jacob, Bhanu Kanth Manne, Elizabeth Kolawole, Emilia A Tugolukova, Siqi Guo, Yasuhiro Kosaka, Cindy Barba, Brian Evavold, Sharon Celesty Morley, Robert A. Campbell, Paul F. Bray
Publikováno v:
Blood. 140:5510-5511
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317ea45eff75a8c455a3c7ecbc860df2
https://doi.org/10.1182/blood-2022-169517
https://doi.org/10.1182/blood-2022-169517
Autor:
Oliver Borst, Matthew T. Rondina, Bhanu Kanth Manne, Andrew S. Weyrich, Seema Bhatlekar, Elizabeth A. Middleton
Publikováno v:
J Thromb Haemost
Background Regulated protein synthesis is essential for megakaryocyte (MK) and platelet functions, including platelet production and activation. PDK1 (phosphoinositide-dependent kinase 1) regulates platelet functional responses and has been associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb6f5b5ba35ab3c9818e87083c846e3
https://doi.org/10.1111/jth.14748
https://doi.org/10.1111/jth.14748
Autor:
Matthew T. Rondina, Bhanu Kanth Manne, Irina Portier, Alicia S. Eustes, Robert A. Campbell, Frederik Denorme, Yasuhiro Kosaka, Benjamin T. Kile
Publikováno v:
Blood. 135:429-440
Dysregulated platelet functions contribute to the development and progression of ischemic stroke. Utilizing mice with a platelet-specific deletion of cyclophilin D (CypD), a mediator of necrosis, we found that platelet necrosis regulates tissue damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b681b9ef1bd7420bfcc5e3cd19d192
https://doi.org/10.1182/blood.2019002124
https://doi.org/10.1182/blood.2019002124