RUVBL1 is an amplified epigenetic factor promoting proliferation and inhibiting differentiation program in head and neck squamous cancers

Autor: Lin, Derrick, Lin, Brian, Bhanot, Haymanti, Riou, Rozenn, Abt, Nicholas B., Rajagopal, Jayaraj, Saladi, Srinivas Vinod

Publikováno v: In Oral Oncology December 2020 111

A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells

Autor: Bhanot Haymanti, Young Ashley M, Overmeyer Jean H, Maltese William A

Publikováno v: Molecular Cancer, Vol 10, Iss 1, p 69 (2011)

Abstract Background Methuosis is a unique form of non-apoptotic cell death triggered by alterations in the trafficking of clathrin-independent endosomes, ultimately leading to extreme vacuolization and rupture of the cell. Results Here we describe a

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chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells.

Autor: Overmeyer, Jean H., Young, Ashley M., Bhanot, Haymanti, Maltese, William A.

Publikováno v: Molecular Cancer; 2011, Vol. 10 Issue 1, p69-85, 17p

Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells.

Autor: Bhanot H; Department of Medical Oncology, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Reddy MM; Department of Medical Oncology, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Nonami A; Department of Medical Oncology, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Weisberg EL; Department of Medical Oncology, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Bonal D; Center for Biomedical Imaging in Oncology (CBIO), Lurie Family Imaging Center (LFIC), Boston, MA, 02215, USA., Kirschmeier PT; Center for Biomedical Imaging in Oncology (CBIO), Lurie Family Imaging Center (LFIC), Boston, MA, 02215, USA., Salgia S; Department of Medical Oncology, Boston, MA, 02215, USA., Podar K; National Center for Tumor Diseases (NCT), Heidelberg, Germany.; University of Heidelberg, German Cancer Research Center (DKFZ), Heidelberg, Germany., Galinsky I; Department of Medical Oncology, Boston, MA, 02215, USA., Chowdary TK; School of Biological Sciences, National Institute of Science Education & Research, Bhubaneswar, India., Neuberg D; Department of Biostatistics and Computational Biology Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Tonon G; San Raffaele Scientific Institute, Milan, Italy., Stone RM; Department of Medical Oncology, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Asara J; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.; Division of Signal Transduction/Mass Spectrometry Core, Beth Israel Deaconess Medical Center, Boston, MA02215, USA., Griffin JD; Department of Medical Oncology, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Sattler M; Department of Medical Oncology, Boston, MA, 02215, USA.; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.

Publikováno v: Leukemia [Leukemia] 2015 Jul; Vol. 29 (7), pp. 1555-1563. Date of Electronic Publication: 2015 Feb 23.