Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Bhakti R Pathak"'
Autor:
Jenifer H Anklesaria, Dhanashree D Jagtap, Bhakti R Pathak, Kaushiki M Kadam, Shaini Joseph, Smita D Mahale
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58631 (2013)
Prostate Secretory Protein of 94 amino acids (PSP94) is one of the major proteins present in the human seminal plasma. Though several functions have been predicted for this protein, its exact role either in sperm function or in prostate pathophysiolo
Externí odkaz:
https://doaj.org/article/e67ec28250434b88a1169a0fad1e8199
Publikováno v:
Archives of Gynecology and Obstetrics. 306:639-662
Publikováno v:
Archives of gynecology and obstetrics. 306(3)
Ovarian cancer is usually detected at an advanced stage with frequent recurrence. The recurrence-free survival and overall survival is influenced by the age at diagnosis, tumor stage and histological subtype. Nonetheless, quantifiable prognostic biom
Autor:
Smita D. Mahale, Bhakti R. Pathak, Sanjana Rane, Shaini Joseph, Ananya A. Breed, Pradnya R. Kamble
Publikováno v:
FEBS lettersReferences. 594(19)
Proteolytic processing is an important post-translational modification affecting protein activity and stability. In the current study, we investigate the N-terminal cleavage of Trop2, a protein which is overexpressed in many cancers. We demonstrate t
Publikováno v:
Archives of Biochemistry and Biophysics. 714:109084
Trophoblast antigen 2 (Trop2) is a type I transmembrane protein post-translationally modified by N-linked glycosylation. It was originally detected in trophoblasts but was later shown to be frequently overexpressed in many epithelial cancers. Recentl
Publikováno v:
General and Comparative Endocrinology. 246:331-336
Follicle-stimulating hormone (FSH) is essential for mammalian folliculogenesis and spermatogenesis. Common marmoset (Callithrix jacchus) is a New World primate which exhibits an unusual FSH profile across the ovarian cycle with a mid-follicular FSH p
Publikováno v:
Molecular and Cellular Endocrinology. 440:69-79
Naturally occurring mutations in follicle stimulating hormone receptor (FSHR) affect the receptor function. Here, we characterized two such previously reported mutations, V221G and T449N, in the extracellular domain and transmembrane helix 3, of FSHR
Autor:
Bhalchandra J. Kulkarni, Bhakti R. Pathak, Susha S. Kutteyil, Shaini Joseph, Rahul Mojidra, Smita D. Mahale
Publikováno v:
Journal of Peptide Science. 22:397-405
Follicle stimulating hormone (FSH) is a glycoprotein hormone required for female and male gametogenesis in vertebrates. Common marmoset (Callithrix jacchus) is a New World primate monkey, used as animal model in biomedical research. Observations like
Publikováno v:
Journal of Peptide Science. 22:383-390
Cysteine-rich secretory proteins (CRISPs) are mainly found in the mammalian male reproductive tract and reported to be involved at different stages of fertilization. CRISPs have been shown to interact with prostate secretory protein of 94 amino acids
Publikováno v:
Molecular and Cellular Biochemistry. 411:11-21
Cysteine-rich secretory protein 3 (CRISP-3) is upregulated in prostate cancer as compared to the normal prostate tissue. Higher expression of CRISP-3 has been linked to poor prognosis and hence it has been thought to act as a prognostic marker for pr