Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bhagyashri V. SirDeshpande"'
Publikováno v:
Biochemistry. 34:9177-9184
The cytotoxic and immunosuppressive marine depsipeptide didemnin B is a potent inhibitor of protein biosynthesis in intact cells. Here, didemnin B is shown to inhibit protein synthesis in vitro during the elongation cycle, by preventing eukaryotic el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7171a92619a2ec616e38ee74dc170928
https://doi.org/10.1021/bi00028a030
https://doi.org/10.1021/bi00028a030
Autor:
Amy J. Pfizenmayer, Matthew D. Vera, Madeleine M. Joullié, Mohamed E. Abazeed, Joshi M. Ramanjulu, Peter L. Toogood, David R. Beidler, Daniel J. Krosky, Deepika Ahuja, Bhagyashri V. SirDeshpande, Adam Geiger
Publikováno v:
Journal of medicinal chemistry. 43(22)
Synthetic and naturally occurring didemnins are potent and specific inhibitors of protein synthesis in vitro. Structure-activity analysis indicates a requirement for the intact macrocycle; however, the smaller ring size represented by the didemnin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6552d7ea3f98fad4d63af37bbe2b2b56
https://pubmed.ncbi.nlm.nih.gov/11063617
https://pubmed.ncbi.nlm.nih.gov/11063617
Autor:
Bhagyashri V. SirDeshpande, Phillip G. Williams, Hiromi Morimoto, Matthew D. Vera, and Madeleine M. Joullié, Deepika Ahuja, Peter L. Toogood
Publikováno v:
Biochemistry. 39(15)
The antineoplastic cyclic depsipeptide didemnin B (DB) inhibits protein synthesis in cells and in vitro. The stage at which DB inhibits protein synthesis in cells is not known, although dehydrodidemnin B arrests translation at the stage of polypeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd64ddda1f89c2eee93446e0af1b0bf
https://pubmed.ncbi.nlm.nih.gov/10757982
https://pubmed.ncbi.nlm.nih.gov/10757982