Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bhagwant Rege"'
Autor:
Chetan P. Kulkarni, Jia Yang, Megan L. Koleske, Giovanni Lara, Khondoker Alam, Andre Raw, Bhagwant Rege, Liang Zhao, Dongmei Lu, Lei Zhang, Lawrence X. Yu, Robert A. Lionberger, Kathleen M. Giacomini, Deanna L. Kroetz, Sook Wah Yee
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 647 (2024)
The presence of mutagenic and carcinogenic N-nitrosamine impurities in medicinal products poses a safety risk. While incorporating antioxidants in formulations is a potential mitigation strategy, concerns arise regarding their interference with drug
Externí odkaz:
https://doaj.org/article/db2f7b3198274994a190b6df5cb02c07
Publikováno v:
International Journal of Pharmaceutics. 452:73-81
The goal of this study was to demonstrate that MK-0364 solid dispersions can be developed as a means to increase the solubility and bioavailability of a poorly water-soluble drug, MK-0364. The potential solid dispersions would enable an oral solid do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f1d321d215b7e3147af4a2855a99b9
https://doi.org/10.1016/j.ijpharm.2013.04.037
https://doi.org/10.1016/j.ijpharm.2013.04.037
Autor:
Rajneesh Taneja, Laxmikant Gharat, Natthida Weerapreeyakul, James E. Polli, Prashant J. Chikhale, Bhagwant Rege
Publikováno v:
International Journal of Pharmaceutics. 219:1-10
We demonstrate transport across, intracellular accumulation and bioreductive activation of a conformationally constrained, anticancer drug delivery system (the CH 3 -TDDS) using Caco-2 cell monolayers (CCMs) as an in vitro model of the human intestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e23d8b66a3ce69912d5c0700a4fe5c
https://doi.org/10.1016/s0378-5173(01)00599-3
https://doi.org/10.1016/s0378-5173(01)00599-3
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