Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Bhagavathi A. Narayanan"'
Autor:
Hideki Mori, George Miller, Kazuhiro Kunimasa, Bhagavathi A. Narayanan, Upender Manne, Mari Mori, Kazuki Nakamura, Amit K. Tiwari, Narayanan K. Narayanan, Yukio Yamori
Publikováno v:
Cancer Medicine
Melinjo (Gnetum gnemon L.) seed extract (MSE) and its active ingredient gnetin C (GC), a resveratrol dimer, have been shown to possess a broad spectrum of pharmacological activities. In this study, we investigated the antitumor activity of MSE and GC
Autor:
Bhagavathi A. Narayanan, Amit K. Tiwari, Jesika S. Faridi, Ritu Malla, Narayanan K. Narayanan, Charles R. Ashby
Publikováno v:
Biochemical and Biophysical Research Communications. 463:161-166
Dysregulation of PI3K-AKT-mTOR pathway has been reported in various pathologies, such as cancer and insulin resistance. The proline-rich AKT substrate of 40-kDa (PRAS40), also known as AKT substrate 1 (AKT1S1), lies at the crossroads of these cascade
Publikováno v:
International Journal of Cancer. 125:1-8
Increasing interest in the use of phytochemicals to reduce prostate cancer led us to investigate 2 potential agents, curcumin and resveratrol as preventive agents. However, there is concern about the bioavailability of these agents pertinent to the p
Autor:
Bhagavathi A. Narayanan, Narayanan K. Narayanan, Maarten C. Bosland, Bandaru S. Reddy, Dominick Nargi, Lori Horton
Publikováno v:
The Prostate. 69:133-141
BACKGROUND Prostate tissue microenvironment is susceptible to several risk factors including carcinogens, dietary factors, hormones, cytokines and growth factors that could induce chronic inflammation. Because of the difference in the serum levels an
Publikováno v:
Journal of Postgenomics Drug & Biomarker Development.
Autor:
Bhagavathi A. Narayanan, Narayanan K. Narayanan, Dhimant Desai, Bandaru S. Reddy, Brian Pittman
Publikováno v:
Carcinogenesis. 25:2443-2449
Epidemiological and preclinical studies suggest that diets that are rich in n-3 polyunsaturated fatty acids (PUFAs) and selenium (Se) reduce the risk of colon cancer. Studies conducted in our laboratory have indicated that synthetic organoselenium 1,
Publikováno v:
Clinical Cancer Research. 10:7727-7737
Purpose: Epidemiologic studies have revealed a decreased risk of colon cancer among people who have regularly taken cyclooxygenase (COX)-2 inhibitors such as aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Whereas the selective COX-2
Autor:
Narayanan K, Narayanan, Bin, Duan, Jonathan T, Butcher, Amitabha, Mazumder, Bhagavathi A, Narayanan
Publikováno v:
In vivo (Athens, Greece). 28(1)
Emerging interest on three-dimensional (3D) cell culture models to replace two-dimensional cultures of cancer cells and their xenografts in immunocompromised animal hosts prompted us to investigate the use of new biodegradable gels to recapitulate th
Publikováno v:
Cancer Letters. 136:215-221
Ellagic acid is a phenolic compound present in fruits and nuts including raspberries, strawberries and walnuts. It is known to inhibit certain carcinogen-induced cancers and may have other chemopreventive properties. The effects of ellagic acid on ce
Publikováno v:
Life Sciences. 63:565-573
Retinoids, including natural vitamin A and its analogs, have been closely studied as chemopreventive drugs. The mechanism of action of retinoids, however, is not completely understood. Our study evaluated the effects of all-trans (high affinity ligan