Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bhadresh, Rami"'
Autor:
Poonam Giri, Debdutta Bandyopadhyay, Sameer Agarwal, Suresh Giri, Prashant K. Deshmukh, Mukul R. Jain, Santosh Sasane, Bhadresh Rami, Ranjit C. Desai
Publikováno v:
ACS medicinal chemistry letters. 7(12)
GPR40/FFAR1 is a G protein-coupled receptor predominantly expressed in pancreatic β-cells and activated by long-chain free fatty acids, mediating enhancement of glucose-stimulated insulin secretion. A novel series of substituted 3-(4-aryloxyaryl)pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1347723defed72729300974072127715
https://pubmed.ncbi.nlm.nih.gov/27994752
https://pubmed.ncbi.nlm.nih.gov/27994752
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
RVFV NP characterization using an immunoprecipitation assay and proteinase K digestion (PK). Upper drawing: schematic illustration of the glycerol gradient profiles, which consist of two distinct sedimentation peaks representing putative assembly int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709b1540dba55520c7c0377b189b1127
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Glycerol gradient fractions of CFPS and 293 HEK cells expressing RVFV NPs WT and mutants. (A) Radioactively labeled RVFV NRP was translated in 26 °C for an hour and run onto a sucrose gradient. First top fraction (F1) or 2nd top fraction (F2) were r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0645cabbf811a6f7b1606e18a72d4d9d
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Specificity of various antibodies against RVFV NP tested by immunoprecipitation of the radiolabeled CFPS RVFV NP. (A) In all lanes, immunoprecipitated CFPS RVFV NPs were loaded, with the exception of lane 4, which represents the total material before
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d6727eaef07b217fc5f2bd84997e18
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Glycerol gradient fractions of CFPS-generated RVFV NPs obtained by increasing the duration and temperature of the translation reaction. A) Glycerol gradient sedimentation of the reactions carried out at 26 °C for increasing durations of translation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3132ee7aee79d3161fbede7699109558
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Conversion of the IOAS into IHOS by nonradioactive CFPS-products is not affected by Apyrase. Glycerol-gradient fractionation profiles of the radioactive material generated in CFPs under conditions favoring intermediate-assembly structures and “chas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c704a9ee1dce070b461cfe4b484eca
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Full conversion of the intermediate capsid structures into highly ordered capsids by nonradioactive CFPS-products. Glycerol-gradient fractionation profiles of the radioactive material generated by CFPS under conditions favoring intermediate-assembly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987f13f7cc8f86a98434af6ec7ae0482
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Glycerol gradient profiles of various CFPS-generated NPs obtained by translation/transcription of different virus families. Nucleoproteins (NP) of Hepatitis C virus (HCV), RVFV, Hantaan virus (HNTN) and Lassa fever virus (LASV) were translated for 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c0bc73569b793aeec2129f6e9f9d7f
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Cell fractionation indicates that the compounds access the nucleus. The most potent compounds were exposed to HEK cells at a concentration of 1Â ÎźM for 24Â h, after which the nucleus was separated from the cytoplasm. The concentration of these t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1804b184434d29897e265c0da84e3a44
Autor:
Broce, Sean, Hensley, Lisa, Tomoharu Sato, Lehrer-Graiwer, Joshua, Essrich, Christian, Edwards, Katie, Pajda, Jacqueline, Davis, Christopher, Bhadresh, Rami, Hurt, Clarence, Freeman, Beverly, Vishwanath Lingappa, Kelleher, Colm, Karpuj, Marcela
Transcript concentration in the in vitro translation reaction affects RVFV NP distribution on the sucrose gradients. Note that the amplitude of peak II (see Additional file 3: figure S3), representing high-order assembly structures, required higher a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d81101f5fc0987b56799366db17232b