Transient pacing in pigs with complete heart block via myocardial injection of mRNA coding for the T-box transcription factor 18.

Autor: Wolfson DW; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Kim NK; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Lee KH; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.; Chonnam National University Medical School, Gwangju, South Korea., Beyersdorf JP; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Langberg JJ; Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA., Fernandez N; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Choi D; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Zureick N; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Kim TY; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Bae S; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.; Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA., Gu JM; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Kirschman JL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Fan J; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.; Division of Pediatric Cardiac Surgery, Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA., Sheng CY; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Gottlieb Sen D; Division of Pediatric Cardiac Surgery, Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA., Mettler B; Division of Pediatric Cardiac Surgery, Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA., Sung JH; Department of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea., Yoon YS; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.; Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA., Park SJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA. Philip.J.Santangelo@emory.edu., Cho HC; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA. HeeCheol.Cho@jhu.edu.; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA. HeeCheol.Cho@jhu.edu.; Division of Pediatric Cardiac Surgery, Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA. HeeCheol.Cho@jhu.edu.; Blalock-Taussig-Thomas Pediatric and Congenital Heart Center, The Johns Hopkins Children's Center, Baltimore, MD, USA. HeeCheol.Cho@jhu.edu.; Department of Biomedical Engineering, Johns Hopkins Whiting School of Engineering, Baltimore, MD, USA. HeeCheol.Cho@jhu.edu.; Department of Anesthesia and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA. HeeCheol.Cho@jhu.edu.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2024 Sep; Vol. 8 (9), pp. 1124-1141. Date of Electronic Publication: 2024 May 02.

Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators.

Autor: Beyersdorf JP; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Krone Engineering Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia 30332, United States., Bawage S; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Krone Engineering Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia 30332, United States., Iglesias N; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, United States., Peck HE; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Krone Engineering Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia 30332, United States., Hobbs RA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Krone Engineering Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia 30332, United States., Wroe JA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Krone Engineering Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia 30332, United States., Zurla C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Krone Engineering Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia 30332, United States., Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, United States.; Center for Advanced Genomic Technologies, Duke University, Durham, North Carolina 27708, United States.; Department of Surgery, Duke University Medical Center, Durham, North Carolina 27708, United States., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Krone Engineering Biosystems Building, 950 Atlantic Drive NW, Atlanta, Georgia 30332, United States.

Publikováno v: ACS nano [ACS Nano] 2022 Apr 26; Vol. 16 (4), pp. 5660-5671. Date of Electronic Publication: 2022 Mar 31.