Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii.

Autor: Jonkergouw C; Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Kemistintie 1, 02150, Espoo, Finland. chris@jonkergouw.nl., Beyeh NK; Oakland University, Department of Chemistry, 146 Library Drive, Rochester, MI, 48309-4479, USA.; Aalto University, School of Science, Department of Applied Physics, Puumiehenkuja 2, Espoo, Finland., Osmekhina E; Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Kemistintie 1, 02150, Espoo, Finland., Leskinen K; University of Helsinki, Translational Immunology Research Program, Haartmaninkatu 8, 0014, Helsinki, Finland., Taimoory SM; University of Windsor, Department of Chemistry and Biochemistry, Windsor, ON, N9B 3P4, Canada.; University of Michigan, Department of Chemistry, Ann Arbor, MI, USA., Fedorov D; Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Kemistintie 1, 02150, Espoo, Finland., Anaya-Plaza E; Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Kemistintie 1, 02150, Espoo, Finland., Kostiainen MA; Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Kemistintie 1, 02150, Espoo, Finland., Trant JF; University of Windsor, Department of Chemistry and Biochemistry, Windsor, ON, N9B 3P4, Canada., Ras RHA; Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Kemistintie 1, 02150, Espoo, Finland.; Aalto University, School of Science, Department of Applied Physics, Puumiehenkuja 2, Espoo, Finland., Saavalainen P; University of Helsinki, Translational Immunology Research Program, Haartmaninkatu 8, 0014, Helsinki, Finland. paivi.saavalainen@helsinki.fi.; Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland. paivi.saavalainen@helsinki.fi., Linder MB; Aalto University, School of Chemical Engineering, Department of Bioproducts and Biosystems, Kemistintie 1, 02150, Espoo, Finland. markus.linder@aalto.fi.

Publikováno v: Nature communications [Nat Commun] 2023 Apr 14; Vol. 14 (1), pp. 2141. Date of Electronic Publication: 2023 Apr 14.

Divalent Benzimidazolium-Based Axles for Self-Reporting Pseudorotaxanes.

Autor: Taimoory SM; Department of Chemistry and Biochemistry, University of Windsor, 401 Sunset Ave., Windsor, ON N9B 3P4, Canada.; Department of Chemistry, University of Michigan, 930 N. University Ave., 2006B, Ann Arbor, Michigan 48109, United States., Yu X; Department of Chemistry and Biochemistry, University of Windsor, 401 Sunset Ave., Windsor, ON N9B 3P4, Canada., Beyeh NK; Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States., Nasri S; Department of Chemistry and Biochemistry, University of Windsor, 401 Sunset Ave., Windsor, ON N9B 3P4, Canada., Trant JF; Department of Chemistry and Biochemistry, University of Windsor, 401 Sunset Ave., Windsor, ON N9B 3P4, Canada.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2022 Dec 02; Vol. 87 (23), pp. 15783-15795. Date of Electronic Publication: 2022 Nov 15.

Simultaneous Organic and Inorganic Host-Guest Chemistry within Pillararene-Protein Cage Frameworks.

Autor: Shaukat A; Department of Bioproducts and Biosystems, Aalto University, 02150, Espoo, Finland., Anaya-Plaza E; Department of Bioproducts and Biosystems, Aalto University, 02150, Espoo, Finland., Beyeh NK; Department of Chemistry, Oakland University, 146 Library Drive, Rochester, MI, 48309-4479, USA., Kostiainen MA; Department of Bioproducts and Biosystems, Aalto University, 02150, Espoo, Finland.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Feb 19; Vol. 28 (11), pp. e202104341. Date of Electronic Publication: 2022 Feb 02.

Functionalized resorcinarenes effectively disrupt the aggregation of αA66-80 crystallin peptide related to cataracts.

Autor: Twum K; Department of Chemistry, Oakland University 146 Library Drive Rochester MI 48309-4479 USA beyeh@oakland.edu., Bhattacharjee A; Department of Chemistry, Portland State University 1710 SW 10th Ave Portland OR 97201 USA., Laryea ET; Department of Chemistry, Oakland University 146 Library Drive Rochester MI 48309-4479 USA beyeh@oakland.edu., Esposto J; Department of Forensic Science and Environmental and Life Sciences Program, Trent University ON K9 L0G2 Canada sanelamartic@trentu.ca., Omolloh G; Department of Chemistry, Portland State University 1710 SW 10th Ave Portland OR 97201 USA., Mortensen S; Department of Forensic Science and Environmental and Life Sciences Program, Trent University ON K9 L0G2 Canada sanelamartic@trentu.ca., Jaradi M; Department of Chemistry, Oakland University 146 Library Drive Rochester MI 48309-4479 USA beyeh@oakland.edu., Stock NL; Water Quality Centre, Trent University ON K9L 0G2 Canada., Schileru N; Department of Chemistry, Oakland University 146 Library Drive Rochester MI 48309-4479 USA beyeh@oakland.edu.; Department of Osteopathic Medicine, Midwestern University 555 31st St. Downers Grove IL 60515 USA., Elias B; Department of Chemistry, Oakland University 146 Library Drive Rochester MI 48309-4479 USA beyeh@oakland.edu., Pszenica E; Department of Chemistry, Oakland University 146 Library Drive Rochester MI 48309-4479 USA beyeh@oakland.edu., McCormick TM; Department of Chemistry, Portland State University 1710 SW 10th Ave Portland OR 97201 USA., Martic S; Department of Forensic Science and Environmental and Life Sciences Program, Trent University ON K9 L0G2 Canada sanelamartic@trentu.ca.; Water Quality Centre, Trent University ON K9L 0G2 Canada., Beyeh NK; Department of Chemistry, Oakland University 146 Library Drive Rochester MI 48309-4479 USA beyeh@oakland.edu.

Publikováno v: RSC medicinal chemistry [RSC Med Chem] 2021 Nov 01; Vol. 12 (12), pp. 2022-2030. Date of Electronic Publication: 2021 Nov 01 (Print Publication: 2021).

Bringing a Molecular Plus One: Synergistic Binding Creates Guest-Mediated Three-Component Complexes.

Autor: Taimoory SM; Department of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario N9B 3P4, Canada., Twum K; Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States., Dashti M; Department of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario N9B 3P4, Canada., Pan F; College of Chemistry, Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Central China Normal University, Luoyu Road 152, Wuhan, Hubei Province 430079, People's Republic of China., Lahtinen M; Department of Chemistry, University of Jyvaskyla, P.O. Box 35, FI-40014 Jyväskylä, Finland., Rissanen K; Department of Chemistry, University of Jyvaskyla, P.O. Box 35, FI-40014 Jyväskylä, Finland., Puttreddy R; Department of Chemistry, University of Jyvaskyla, P.O. Box 35, FI-40014 Jyväskylä, Finland.; Faculty of Engineering and Natural Sciences, Tampere University, P.O. Box 541, FI-33101 Tampere, Finland., Trant JF; Department of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario N9B 3P4, Canada., Beyeh NK; Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2020 May 01; Vol. 85 (9), pp. 5884-5894. Date of Electronic Publication: 2020 Mar 31.