Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bewshea, Cm"'
Autor:
Walker, GJ, Harrison, JW, Heap, GA, Voskuil, MD, Andersen, V, Anderson, CA, Ananthakrishnan, AN, Barrett, JC, Beaugerie, L, Bewshea, CM, Cole, AT, Cummings, FR, Daly, MJ, Ellul, P, Fedorak, RN, Festen, EAM, Florin, TH, Gaya, DR, Halfvarson, J, Hart, AL, Heerasing, NM, Hendy, P, Irving, PM, Jones, SE, Koskela, J, Lindsay, JO, Mansfield, JC, McGovern, D, Parkes, M, Pollok, RCG, Ramakrishnan, S, Rampton, DS, Rivas, MA, Russell, RK, Schultz, M, Sebastian, S, Seksik, P, Singh, A, So, K, Sokol, H, Subramaniam, K, Todd, A, Annese, V, Weersma, RK, Xavier, R, Ward, R, Weedon, MN, Goodhand, JR, Kennedy, NA, Ahmad, T, Holden, AL, Andrews, J, Auth, M, Babu, S, Bampton, P, Banim, P, Barnes, T, Basude, D, Beckly, J, Bell, A, Bell, S, Bhandari, P, Bloom, S, Border, D, Bredin, F, Brookes, MJ, Brown, M, Calvert, C, Campbell, D, Chanchlani, N, Chaudhary, B, Chaudhary, R, Chung-Faye, G, Colleypriest, B, Connor, S, Cooney, R, Cooper, S, Creed, TJ, Croft, N, Cullen, S, D'Amato, M, Dalal, H, Daneshmend, TK, Das, D, Delaney, M, Desilva, S, Dhar, A, Dharmasiri, S, Direkze, N, Dunckley, P, Elphick, D, Everett, SM, Feeney, M, Fell, J, Foley, S, Franke, A, Gavin, D, Gee, I, Ghosh, D, Goldsmith, C, Gorard, D, Gordon, JN, Gore, S, Green, J, Grimes, D, Hamill, G, Harbord, M, Hart, J, Hawkey, C, Iqbal, T, Ireland, A, Johnson, M, Jones, C, Kanegasundaram, S, Karban, A, Katsanos, KH, Kiparissi, F, Kirkham, S, Lal, S, Langlands, S, Lawrance, IC, Lees, CW, Lev-Tzion, R, Levison, S, Lewis, SJ, Li, A, Limdi, J, Lin, S, Lobo, A, Lockett, M, Loehry, J, MacDonald, C, MacFaul, G, Mahmood, T, Mann, S, Mawdsley, J, Mazhar, Z, McGovern, JF, McNair, A, Modi, A, Monahan, K, Moran, A, Morris, M-A, Mortimore, M, Mowat, C, Muhammed, R, Murray, CDR, Olivier, H, Orchard, TR, Panter, S, Patel, V, Phillips, R, Prasad, N, Preston, C, Radford-Smith, G, Rajasekhar, P, Roy, D, Saich, R, Satsangi, J, Schreiber, S, Sen, S, Shah, N, Shenderay, R, Shenoy, A, Shutt, J, Silverberg, M, Simmons, A, Simmons, J, Singh, S, Smith, M, Snook, JA, Sonwalker, S, Stevens, CR, Sturniolo, G, Subramanian, S, Thomas, A, Tighe, M, Torrente, F, Tremelling, M, Tsianos, E, Vani, D, Walsh, A, Watermeyer, G, Watts, D, Watts, G, Weaver, S, Wesley, E, Willmott, A, Yearsley, K, Zambar, V, Zeissig, S
Publikováno v:
JAMA, 321(8), 773-785. AMER MEDICAL ASSOC
Funding Information: reported serving as a consultant for AbbVie UK; receiving honoraria from Falk and AbbVie UK; receiving grants from Crohn’s & Colitis UK and Tillott’s Pharmaceuticals; having a fellowship from the UK National Institute for Hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8d78d1552e80b56aa35df97ff0b107
http://hdl.handle.net/10138/308428
http://hdl.handle.net/10138/308428
Autor:
Heap, Ga, Weedon, Mn, Bewshea, Cm, Singh, A, Chen, M, Satchwell, Jb, Vivian, Jp, So, K, Dubois, Pc, Andrews, Jm, Annese, V, Bampton, P, Barnardo, M, Bell, S, Cole, A, Connor, Sj, Creed, T, Cummings, Fr, D'Amato, M, Daneshmend, Tk, Fedorak, Rn, Florin, Th, Gaya, Dr, Greig, E, Halfvarson, J, Hart, A, Irving, Pm, Jones, G, Karban, A, Lawrance, Ic, Lee, Jc, Lees, C, Lev Tzion, R, Lindsay, Jo, Mansfield, J, Mawdsley, J, Mazhar, Z, Parkes, M, Parnell, K, Orchard, Tr, Radford Smith, G, Russell, Rk, Reffitt, D, Satsangi, J, Silverberg, Ms, Sturniolo, Giacomo, Tremelling, M, Tsianos, Ev, van Heel DA, Walsh, A, Watermeyer, G, Weersma, Rk, Zeissig, S, Rossjohn, J, Holden, Al, Ahmad, T, International Serious Adverse Events Consortium, IBD Pharmacogenetics Study Group
Publikováno v:
Nature Genetics, 46(10), 1131-1134. Nature Publishing Group
Pancreatitis occurs in approximately 4% of patients treated with the thiopurines azathioprine or mercaptopurine. Its development is unpredictable and almost always leads to drug withdrawal. We identified patients with inflammatory bowel disease (IBD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4a4c5cf71cb3db2f7d83cf6c417436
https://doi.org/10.1038/ng.3093
https://doi.org/10.1038/ng.3093
Autor:
Alexander JL; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; Department of Gastroenterology and Hepatology, Imperial College Healthcare NHS Trust, London, United Kingdom. Electronic address: j.alexander@imperial.ac.uk., Mullish BH; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; Department of Gastroenterology and Hepatology, Imperial College Healthcare NHS Trust, London, United Kingdom., Danckert NP; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Liu Z; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Olbei ML; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Saifuddin A; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; St Mark's Hospital and Academic Institute, Harrow, London, United Kingdom., Torkizadeh M; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; King's College London, London, United Kingdom., Ibraheim H; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; Department of Gastroenterology and Hepatology, Imperial College Healthcare NHS Trust, London, United Kingdom., Blanco JM; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Roberts LA; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Bewshea CM; University of Exeter, Exeter, Devon, United Kingdom., Nice R; University of Exeter, Exeter, Devon, United Kingdom; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, United Kingdom., Lin S; University of Exeter, Exeter, Devon, United Kingdom; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, United Kingdom., Prabhudev H; Department of Gastroenterology and Hepatology, Imperial College Healthcare NHS Trust, London, United Kingdom., Sands C; National Phenome Centre, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Horneffer-van der Sluis V; National Phenome Centre, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Lewis M; National Phenome Centre, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Sebastian S; Hull University Teaching Hospitals NHS Trust, Gastroenterology, Hull, United Kingdom; University of Hull, Hull York Medical School, Hull, United Kingdom., Lees CW; Western General Hospital, Edinburgh, United Kingdom; The University of Edinburgh Centre for Genomic and Experimental Medicine, Edinburgh, United Kingdom., Teare JP; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Hart A; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; St Mark's Hospital and Academic Institute, Harrow, London, United Kingdom., Goodhand JR; University of Exeter, Exeter, Devon, United Kingdom; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, United Kingdom., Kennedy NA; University of Exeter, Exeter, Devon, United Kingdom; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, United Kingdom., Korcsmaros T; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; Earlham Institute, Norwich, United Kingdom; Quadram Institute Bioscience, Norwich, United Kingdom., Marchesi JR; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom., Ahmad T; University of Exeter, Exeter, Devon, United Kingdom; Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, United Kingdom., Powell N; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom; Department of Gastroenterology and Hepatology, Imperial College Healthcare NHS Trust, London, United Kingdom. Electronic address: nicholas.powell@imperial.ac.uk.
Publikováno v:
EBioMedicine [EBioMedicine] 2023 Feb; Vol. 88, pp. 104430. Date of Electronic Publication: 2023 Jan 10.
Autor:
Walker GJ; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Chanchlani N; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK.; Paediatrics, Royal Devon and Exeter Hospital, Exeter, UK., Thomas A; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Lin S; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Moore L; The College of Medicine & Health, University of Exeter, Exeter, UK., Heerasing NM; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Hendy P; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Abdelrahim M; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK., Mole S; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK., Perry MH; Biochemistry, Royal Devon and Exeter Hospital, Exeter, UK., Mcdonald TJ; The College of Medicine & Health, University of Exeter, Exeter, UK.; Biochemistry, Royal Devon and Exeter Hospital, Exeter, UK., Bewshea CM; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Hart JW; Paediatrics, Royal Devon and Exeter Hospital, Exeter, UK., Russell RK; Paediatric Gastroenterology, The Hospital For Sick Children, Edinburgh, UK., Ahmad T; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Goodhand JR; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK., Kennedy NA; Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK nick.kennedy1@nhs.net.; Exeter IBD Pharmacogenetics, University of Exeter Medical School, Exeter, UK.
Publikováno v:
Archives of disease in childhood [Arch Dis Child] 2020 Oct; Vol. 105 (10), pp. 957-963. Date of Electronic Publication: 2020 May 18.
Autor:
Sazonovs A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Kennedy NA; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Moutsianas L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Heap GA; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; AbbVie Inc, North Chicago, Illinois., Rice DL; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Reppell M; AbbVie Inc, North Chicago, Illinois., Bewshea CM; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Chanchlani N; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Walker GJ; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Perry MH; Department of Blood Science, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK., McDonald TJ; Department of Blood Science, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK., Lees CW; Department of Gastroenterology, Western General Hospital, National Health Service Lothian, Edinburgh, UK., Cummings JRF; Department of Gastroenterology, University Hospital Southampton National Health Service Foundation Trust, Southampton, UK; Faculty of Experimental Medicine, University of Southampton, Southampton, UK., Parkes M; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, UK., Mansfield JC; Department of Gastroenterology, Newcastle Upon Tyne Hospitals National Health Service Foundation Trust, Newcastle upon Tyne, UK., Irving PM; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation, Trust, London, UK., Barrett JC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., McGovern D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Goodhand JR; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK., Anderson CA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. Electronic address: carl.anderson@sanger.ac.uk., Ahmad T; Department of Gastroenterology, Royal Devon and Exeter Hospital National Health Service Foundation Trust, Exeter, UK; Exeter Inflammatory Bowel Disease and Pharmacogenetics Research Group, University of Exeter, Exeter, UK. Electronic address: tariq.ahmad1@nhs.net.
Publikováno v:
Gastroenterology [Gastroenterology] 2020 Jan; Vol. 158 (1), pp. 189-199. Date of Electronic Publication: 2019 Oct 07.
Autor:
Walker GJ; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.; IBD Pharmacogenetics Group, University of Exeter, Exeter, England., Harrison JW; University of Exeter Medical School, Exeter, England., Heap GA; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.; IBD Pharmacogenetics Group, University of Exeter, Exeter, England., Voskuil MD; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands., Andersen V; Medical Department, Regional Hospital Viborg, Viborg, Denmark., Anderson CA; Wellcome Trust Sanger Institute, Hinxton, England., Ananthakrishnan AN; Department of Gastroenterology, Massachusetts General Hospital, Boston., Barrett JC; Wellcome Trust Sanger Institute, Hinxton, England., Beaugerie L; Department of Gastroenterology, Saint-Antoine Hospital and Sorbonne Universite, Paris, France., Bewshea CM; IBD Pharmacogenetics Group, University of Exeter, Exeter, England., Cole AT; Derby Digestive Diseases Centre, Royal Derby Hospital, Derby Teaching Hospitals NHS Foundation Trust, Derby, England., Cummings FR; Department of Gastroenterology, Southampton General Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, England., Daly MJ; Broad Institute, Harvard University, Cambridge, Massachusetts., Ellul P; Department of Gastroenterology, Mater Dei Hospital, Msida, Malta., Fedorak RN; Division of Gastroenterology, University of Alberta, Edmonton, Canada., Festen EAM; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands., Florin TH; Mater Research Institute, University of Queensland, South Brisbane, Australia., Gaya DR; Department of Gastroenterology, Glasgow Royal Infirmary, NHS Greater Glasgow and Clyde, Glasgow, Scotland., Halfvarson J; Division of Gastroenterology, Örebro University, Örebro, Sweden., Hart AL; Department of Gastroenterology, St Mark's Hospital, London North West Healthcare NHS Trust, Harrow, England., Heerasing NM; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.; IBD Pharmacogenetics Group, University of Exeter, Exeter, England., Hendy P; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.; IBD Pharmacogenetics Group, University of Exeter, Exeter, England., Irving PM; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, England., Jones SE; University of Exeter Medical School, Exeter, England., Koskela J; Broad Institute, Harvard University, Cambridge, Massachusetts., Lindsay JO; Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, England., Mansfield JC; Department of Gastroenterology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England., McGovern D; F. Widjaja Foundation Inflammatory Bowel Disease and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Parkes M; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England., Pollok RCG; Department of Gastroenterology, St George's Healthcare NHS Trust, Tooting, England., Ramakrishnan S; Gastrointestinal and Liver Services, Warrington and Halton Hospitals NHS Foundation Trust, Warrington, England., Rampton DS; Department of Gastroenterology, Royal London Hospital, Barts Health NHS Trust, London, England., Rivas MA; Broad Institute, Harvard University, Cambridge, Massachusetts., Russell RK; Department of Paediatric Gastroenterology, Royal Hospital for Children, NHS Greater Glasgow and Clyde, Glasgow, Scotland., Schultz M; Dunedin Hospital, Dunedin, New Zealand., Sebastian S; Gastroenterology and Hepatology, Hull and East Yorkshire Hospitals NHS Trust, Hull, England., Seksik P; Department of Gastroenterology, Saint-Antoine Hospital and Sorbonne Universite, Paris, France., Singh A; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England., So K; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England., Sokol H; Department of Gastroenterology, Saint-Antoine Hospital and Sorbonne Universite, Paris, France., Subramaniam K; Canberra Hospital, Canberra, Australia., Todd A; Department of Haematology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England., Annese V; Division of Gastroenterology, Azienda Ospedaliero Universitaria Careggi, Florence, Italy., Weersma RK; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands., Xavier R; Broad Institute, Harvard University, Cambridge, Massachusetts., Ward R; University of Exeter Medical School, Exeter, England., Weedon MN; University of Exeter Medical School, Exeter, England., Goodhand JR; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.; IBD Pharmacogenetics Group, University of Exeter, Exeter, England., Kennedy NA; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.; IBD Pharmacogenetics Group, University of Exeter, Exeter, England., Ahmad T; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.; IBD Pharmacogenetics Group, University of Exeter, Exeter, England.
Publikováno v:
JAMA [JAMA] 2019 Feb 26; Vol. 321 (8), pp. 773-785.