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Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies.

Autor: Joisa CU; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA and North Carolina State University, Raleigh, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chen KA; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beville S; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Stuhlmiller T; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Berginski ME; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Okumu D; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Golitz BT; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Johnson GL; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gomez SM; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA and North Carolina State University, Raleigh, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 03. Date of Electronic Publication: 2023 Aug 03.