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Pharmacokinetics and Associated Efficacy of Emicizumab in Humans: A Systematic Review

Autor: Donners, Anouk A M T, Rademaker, Carin M A, Bevers, Lisanne A H, Huitema, Alwin D R, Schutgens, Roger E G, Egberts, Toine C G, Fischer, Kathelijn, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

Publikováno v: Clinical Pharmacokinetics
Clinical Pharmacokinetics, 60(11), 1395. Adis International Ltd

Introduction Emicizumab is an effective new treatment option for people with hemophilia A (PwHA). The approved dosing regimens are based on body weight, without the necessity for laboratory monitoring. This assumes a clear dose–concentration–resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b994b3453534c3eea4fc89142f0b102
https://dspace.library.uu.nl/handle/1874/416223

Pharmacokinetics and Associated Efficacy of Emicizumab in Humans: A Systematic Review.

Autor: Donners AAMT; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, D.00.204, Postbus 85500, 3508 GA, Utrecht, The Netherlands. a.a.m.donners@umcutrecht.nl., Rademaker CMA; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, D.00.204, Postbus 85500, 3508 GA, Utrecht, The Netherlands., Bevers LAH; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, D.00.204, Postbus 85500, 3508 GA, Utrecht, The Netherlands., Huitema ADR; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, D.00.204, Postbus 85500, 3508 GA, Utrecht, The Netherlands.; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Pharmacology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Schutgens REG; Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Egberts TCG; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, D.00.204, Postbus 85500, 3508 GA, Utrecht, The Netherlands.; Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Fischer K; Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Clinical pharmacokinetics [Clin Pharmacokinet] 2021 Nov; Vol. 60 (11), pp. 1395-1406. Date of Electronic Publication: 2021 Aug 13.