Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Beverly Z. Packard"'
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical CytologyLiterature Cited. 97(9)
The measurement of mRNA transcripts in live cells has been limited by inefficient delivery vehicles for oligonucleotides. Using a delivery platform which utilizes fluorophores capable of forming intramolecular H-type excitonic dimers, we show that an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d49343b44e8d69e572f14385702ec60
https://pubmed.ncbi.nlm.nih.gov/32588516
https://pubmed.ncbi.nlm.nih.gov/32588516
Autor:
Jens H. Kuhn, Julie P. Tran, Sheli R. Radoshitzky, Rajini Mudhasani, Sina Bavari, Krishna P. Kota, I-Chueh Huang, Louis A. Altamura, Aura R. Garrison, Beverly Z. Packard, Michael Farzan, Jeffrey M. Smith, Cary Retterer, Julie Costantino, Connie S. Schmaljohn
Publikováno v:
Journal of Virology. 87:8451-8464
We show that interferon-induced transmembrane protein 1 (IFITM-1), IFITM-2, and IFITM-3 exhibit a broad spectrum of antiviral activity against several members of the Bunyaviridae family, including Rift Valley fever virus (RVFV), La Crosse virus, Ande
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203aa6275c5a1763eaeffe506bb66506
https://doi.org/10.1128/jvi.03382-12
https://doi.org/10.1128/jvi.03382-12
Autor:
Rohan P. Joshi, Amy M. Berkley, John M. Coffin, Kristin A. Weeks, Jo Ann M. Mican, Dean Follman, Julia E. Rood, Stephen A. Migueles, Frank Maldarelli, Richard Kwan, John W. Mellors, Jonah B. Sacha, Akira Komoriya, Christine M. Osborne, Sara Stallings, Mark Connors, Catherine Rehm, Margaret Lloyd, Nancy A. Cogliano-Shutta, Alex A. Compton, Claire W. Hallahan, Cassandra Royce, Beverly Z. Packard, Ann Wiegand, Marie A. O'Shea, Sarah Palmer, Mary McLaughlin, Gregg Roby
Publikováno v:
Immunity. 29(6):1009-1021
SummaryVirus-specific CD8+ T cells probably mediate control over HIV replication in rare individuals, termed long-term nonprogressors (LTNPs) or elite controllers. Despite extensive investigation, the mechanisms responsible for this control remain in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eadbfe273816803b99941de2ab88b2
Autor:
Beverly Z. Packard, Akira Komoriya
Publikováno v:
Cell Research. 18:238-247
Over the past decade the importance of signaling from reporter molecules inside live cells and tissues has been clearly established. Biochemical events related to inflammation, tumor metastasis and proliferation, and viral infectivity and replication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de7227dfbe5b4aad40f3dcf4f737d24
https://doi.org/10.1038/cr.2008.17
https://doi.org/10.1038/cr.2008.17
Publikováno v:
Experimental Cell Research. 289:384-395
Molecular studies of the physiological cell death process have focused attention on the role of effector caspases as critical common elements of the lethal mechanism. Diverse death signals act afferently via distinct signaling pathways to activate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e45f1abdd42ce5a78300d8047d6f1bc
https://doi.org/10.1016/s0014-4827(03)00289-1
https://doi.org/10.1016/s0014-4827(03)00289-1
Autor:
Mark B. Feinberg, Luzheng Liu, Beverly Z. Packard, Guido Silvestri, Akira Komoriya, Jeffrey T. Safrit, Mary E Wernett, Ann Chahroudi, William J. Kaiser, John D. Altman
Publikováno v:
Nature Medicine. 8:185-189
We have developed a non-radioactive flow-cytometry assay to monitor and quantify the target-cell killing activities mediated by cytotoxic T lymphocytes (CTLs). This flow-cytometry CTL (FCC) assay is predicated on measurement of CTL-induced caspase ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddd021fa757cf6e6ede160459066659
https://doi.org/10.1038/nm0202-185
https://doi.org/10.1038/nm0202-185
Publikováno v:
Cytometry. 47:81-88
Background: Caspase activation is a critical early step in the onset of apoptosis. Cell-permeable fluorogenic caspase substrates have proven valuable in detecting caspase activation by flow cytometry. Nevertheless, detection of early low-level caspas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435a7fbd5bfb9af554c1587c005b3b3d
https://doi.org/10.1002/cyto.10052
https://doi.org/10.1002/cyto.10052
Publikováno v:
Biophysical Chemistry. 71:63-72
Nanosecond fluorescence decay characteristics of the calcium-binding probe Quin2 and two of its cation complexes were examined by time-resolved fluorescence spectroscopy. Binding of Ca2+ and Cd2+ resulted in fluorescence lifetime enhancements as comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4113f98c5f89122e93b271fb63f987d9
https://doi.org/10.1016/s0301-4622(97)00136-1
https://doi.org/10.1016/s0301-4622(97)00136-1
Autor:
Akira Komoriya, Beverly Z. Packard
Publikováno v:
Critical Reviews™ in Immunology. 18:139-144
Phenotypic and functional analyses of tumor-infiltrating lymphocytes (TILs) used in clinical trials revealed that cells other than CTLs can have antitumor efficacy. This observation led us to search for mechanisms for tumor recognition by lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e833942f6b5ffe22b53e43a3a940bd51
https://doi.org/10.1615/critrevimmunol.v18.i1-2.150
https://doi.org/10.1615/critrevimmunol.v18.i1-2.150
Publikováno v:
The Journal of Physical Chemistry B. 102:752-758
In this study NorFES, an undecapeptide containing an amino acid sequence recognized by the serine protease elastase, was covalently labeled with two xanthenes, one on each side of its cleavage site, to serve as a tool for examination of intramolecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d499f9eb2fc5bd5b5780809a332f05d1
https://doi.org/10.1021/jp972845b
https://doi.org/10.1021/jp972845b