Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Beverly Montgomery"'
Autor:
Aline de Conti, Stepan Melnyk, Levan Muskhelishvili, John R. Latendresse, Beverly Montgomery, S. Jill James, Ivan Rusyn, Frederick A. Beland, Marta Pogribna, Volodymyr Tryndyak, Kristy Kutanzi, Igor P. Pogribny
Publikováno v:
The FASEB Journal. 27:2233-2243
Dysregulation of one-carbon metabolism-related metabolic processes is a major contributor to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). It is well established that genetic and gender-specific variations in one-carbon metabolism con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ee1a34b4d6cb1b87aae8acfea9488f
https://doi.org/10.1096/fj.12-227116
https://doi.org/10.1096/fj.12-227116
Autor:
Tetyana V. Bagnyukova, Levan Muskhelishvili, Frederick A. Beland, Smitha R. James, Igor P. Pogribny, Beverly Montgomery, Adam R. Karpf, Volodymyr P. Tryndyak, Mona I. Churchwell
Publikováno v:
Carcinogenesis. 29:638-646
Genotoxic carcinogens, including 2-acetylaminofluorene (2-AAF), in addition to exerting their genotoxic effects, often cause a variety of non-genotoxic alterations in cells. It is believed that these non-genotoxic effects may be indispensable events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538d8a19fbef552cc90e804d14746d2f
https://doi.org/10.1093/carcin/bgm303
https://doi.org/10.1093/carcin/bgm303
Autor:
Igor Kovalchuk, Olga Kovalchuk, Frederick A. Beland, Igor P. Pogribny, Beverly Montgomery, Alex Boyko, Volodymyr Tryndyak, John R. Latendresse, Alan Warbritton, Kristy Kutanzi, Franz J. Zemp
Publikováno v:
Cell Cycle. 6:2010-2018
Breast cancer is the most common malignancy in women continuing to rise worldwide. Breast cancer emerges through a multi-step process, encompassing progressive changes from a normal cell to hyperplasia (with and without atypia), carcinoma in situ, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d69f605add09a0311fd68139838b7f7
https://doi.org/10.4161/cc.6.16.4549
https://doi.org/10.4161/cc.6.16.4549
Autor:
Robert R. Delongchamp, Beverly Montgomery, Scott G. Miller, Bentley A. Fane, Heinrich V. Malling, Carrie R. Valentine
Publikováno v:
Environmental and Molecular Mutagenesis. 39:55-68
The sensitivity of in vivo transgenic mutation assays benefits from the sequencing of mutations, although the large number of possible mutations hinders high throughput sequencing. A forward mutational assay exists for ΦX174 that requires an altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d5575e868abbec317d15726cfbb831
https://doi.org/10.1002/em.10043
https://doi.org/10.1002/em.10043
Autor:
Aline de Conti, Beverly Montgomery, Frederick A. Beland, Volodymyr P. Tryndyak, Daniel R. Doerge, Claudia Escudero-Lourdes, Tetyana Kobets, Igor P. Pogribny
The presence of furan in common cooked foods along with evidence from experimental studies that lifetime exposure to furan causes liver tumors in rats and mice has caused concern to regulatory public health agencies worldwide; however, the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18819268d4a9c893c35885b879a273fe
https://europepmc.org/articles/PMC4064012/
https://europepmc.org/articles/PMC4064012/
Autor:
Igor P. Pogribny, Beverly Montgomery, John R. Latendresse, Volodymyr Tryndyak, Frederick A. Beland, Sharon A. Ross, Ivan Rusyn, Tetyana V. Bagnyukova, Stepan Melnyk
Background/Aims The importance of epigenetic changes in etiology and pathogenesis of disease has been increasingly recognized. However, the role of epigenetic alterations in the genesis of hepatic steatosis and cause of individual susceptibilities to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0999e0ad7f9335572135b91e57fe6ec
Autor:
Igor P. Pogribny, Stepan Melnyk, Volodymyr Tryndyak, Tetyana V. Bagnyukova, Ivan Rusyn, Beverly Montgomery, Anna Boureiko
Genomic hypomethylation is a consistent finding in both human and animal tumors and mounting experimental evidence suggests a key role for epigenetic events in tumorigenesis. Furthermore, it has been suggested that early changes in DNA methylation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d066f661afe995ed227b7cc7a80e919b
Autor:
Beverly Montgomery, Rocio Rodriguez-Juarez, Sharon A. Ross, Frederick A. Beland, Volodymyr Tryndyak, Olga Kovalchuk, Stepan Melnyk, Levan Muskhelishvili, Igor P. Pogribny
Publikováno v:
Molecular carcinogenesis. 46(3)
Tamoxifen, a nonsteroidal anti-estrogen, is a potent genotoxic hepatocarcinogen in rats, with both tumor initiating and promoting properties. Recently it has been demonstrated that genotoxic carcinogens, in addition to exerting genotoxic effects, oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd26d5c515f9353cc9d77a272781821c
https://pubmed.ncbi.nlm.nih.gov/17219426
https://pubmed.ncbi.nlm.nih.gov/17219426
Autor:
Levan Muskhelishvili, Beverly Montgomery, Mona I. Churchwell, Rocio Rodriguez-Juarez, Igor P. Pogribny, Sharon A. Ross, Olga Kovalchuk, Frederick A. Beland, Volodymyr Tryndyak
Publikováno v:
Carcinogenesis. 27(8)
Tamoxifen is a non-steroidal anti-estrogen used for the treatment of breast cancer and, more recently, as a chemopreventive agent in healthy women at high risk of developing breast cancer. On the other hand, tamoxifen is a potent hepatocarcinogen in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba49cfdeca3c492e252d1dba8810d10
https://pubmed.ncbi.nlm.nih.gov/16632870
https://pubmed.ncbi.nlm.nih.gov/16632870