Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Beverly Mok"'
Autor:
Luke W. Koblan, Britt Adamson, Albert Xu, Mandana Arbab, Tyler A Sisley, Jordan L. Doman, Dian Yang, Joseph M. Replogle, David R. Liu, Andrew V. Anzalone, Jeffrey A. Hussmann, Max W. Shen, Gregory A. Newby, Beverly Mok, Jonathan S. Weissman
Publikováno v:
Nature Biotechnology. 39:1414-1425
Programmable C•G-to-G•C base editors (CGBEs) have broad scientific and therapeutic potential, but their editing outcomes have proved difficult to predict and their editing efficiency and product purity are often low. We describe a suite of engine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794631ca2dbb8219581743d613b4016c
https://doi.org/10.1038/s41587-021-00938-z
https://doi.org/10.1038/s41587-021-00938-z
Autor:
Luke W, Koblan, Mandana, Arbab, Max W, Shen, Jeffrey A, Hussmann, Andrew V, Anzalone, Jordan L, Doman, Gregory A, Newby, Dian, Yang, Beverly, Mok, Joseph M, Replogle, Albert, Xu, Tyler A, Sisley, Jonathan S, Weissman, Britt, Adamson, David R, Liu
Publikováno v:
Nature biotechnology. 39(11)
Programmable C•G-to-G•C base editors (CGBEs) have broad scientific and therapeutic potential, but their editing outcomes have proved difficult to predict and their editing efficiency and product purity are often low. We describe a suite of engine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15e36642ea4763069825991aeb0e97f2
https://pubmed.ncbi.nlm.nih.gov/34873327
https://pubmed.ncbi.nlm.nih.gov/34873327
Autor:
Żaneta Matuszek, Mandana Arbab, David R. Liu, Christopher A. Cassa, Beverly Mok, Max W. Shen, Christine D. Wilson
Publikováno v:
Cell. 182(2)
Although base editors are widely used to install targeted point mutations, the factors that determine base editing outcomes are not well understood. We characterized sequence-activity relationships of 11 cytosine and adenine base editors (CBEs and AB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036fd68bdbd6307f39ca41f9066588b5
https://pubmed.ncbi.nlm.nih.gov/32833537
https://pubmed.ncbi.nlm.nih.gov/32833537
Autor:
Beverly Mok, Donghyun Lim, Bishwajit Paul, Soumyashree A. Gangopadhyay, Amedeo Vetere, Bridget K. Wagner, Amit Choudhary, Paul A. Clemons, Vlado Dančík, Luciano A. Marraffini, Peng Wu, Robert Heler, Sachini U. Siriwardena, David R. Liu, Miseon Lee, Michael F. Mesleh, Basudeb Maji, Mengchao Shi
Publikováno v:
Cell. 177:1067-1079.e19
The precise control of CRISPR-Cas9 activity is required for a number of genome engineering technologies. Here, we report a generalizable platform that provided the first synthetic small-molecule inhibitors of Streptococcus pyogenes Cas9 (SpCas9) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c99eaf7b1001b79f1f38ef5021f0621
https://doi.org/10.1016/j.cell.2019.04.009
https://doi.org/10.1016/j.cell.2019.04.009