Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Beverly L Falcon"'
Autor:
Beverly L Falcon, Michelle Swearingen, Wendy H Gough, Linda Lee, Robert Foreman, Mark Uhlik, Jeff C Hanson, Jonathan A Lee, Don B McClure, Sudhakar Chintharlapalli
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106901 (2014)
Vascular endothelial growth factor (VEGF) plays a dominant role in angiogenesis. While inhibitors of the VEGF pathway are approved for the treatment of a number of tumor types, the effectiveness is limited and evasive resistance is common. One mechan
Externí odkaz:
https://doaj.org/article/da954fc5fdb943c6baa8aa37fcd78d65
Autor:
Rupal S. Bhatt, Laura E. Benjamin, David C. Alsop, Damien Gerald, Sudhakar Chintharlapalli, Mark T. Uhlik, Jason Manro, Philip Hipskind, Takako Wilson, Julie Stewart, Glenn Evans, Diane Bodenmiller, Rowena Almonte-Baldonado, Beverly L. Falcon, Xiaoen Wang, Anthony S. Fischl
Inhibition of VEGFR signaling is an effective treatment for renal cell carcinoma, but resistance continues to be a major problem. Recently, the sphingosine phosphate (S1P) signaling pathway has been implicated in tumor growth, angiogenesis, and resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07698e2d3dbef68e4960d1e590a94e57
https://doi.org/10.1158/1535-7163.c.6537817.v1
https://doi.org/10.1158/1535-7163.c.6537817.v1
Autor:
Rupal S. Bhatt, Laura E. Benjamin, David C. Alsop, Damien Gerald, Sudhakar Chintharlapalli, Mark T. Uhlik, Jason Manro, Philip Hipskind, Takako Wilson, Julie Stewart, Glenn Evans, Diane Bodenmiller, Rowena Almonte-Baldonado, Beverly L. Falcon, Xiaoen Wang, Anthony S. Fischl
Figure S2: Co-targeting S1P1 and VEGFR2 pathways induced reduction in permeability of retinal vessels. Ter 119 staining (panels A) visualize red blood cells and show that the combination of DC101 and the S1P1 antagonist in the retina led to reduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f131b36c3fff3a476b481e429735e4
https://doi.org/10.1158/1535-7163.22504639
https://doi.org/10.1158/1535-7163.22504639
Autor:
Laura E. Benjamin, Harold F. Dvorak, Janice A. Nagy, Aejaz Nasir, Fiona Ginty, Shou-ching Jaminet, Bronislaw Pytowski, Julia H. Carter, Amit Aggarwal, Thompson Doman, Keyur Desai, Yunxia Sui, Yousef Al-Kofahi, Alberto Santamaria-Pang, Jee-yun Lee, Qi Xue, Damien Gerald, Anthony Fischl, Sudhakar Chintharlapalli, Diane Bodenmiller, Cynthia Jeffries, Larry Douglass, Christina Lowes, Christopher Sevinsky, Marguerita O'Mahony, Hilal Celikkaya, Julie Stewart, Seema Iyer, Beverly L. Falcon, Jiangang Liu, Mark T. Uhlik
Treatment of metastatic gastric cancer typically involves chemotherapy and monoclonal antibodies targeting HER2 (ERBB2) and VEGFR2 (KDR). However, reliable methods to identify patients who would benefit most from a combination of treatment modalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a006fb70911d8eae8e189a451b1f70
https://doi.org/10.1158/0008-5472.c.6508700.v1
https://doi.org/10.1158/0008-5472.c.6508700.v1
Autor:
Laura E. Benjamin, Harold F. Dvorak, Janice A. Nagy, Aejaz Nasir, Fiona Ginty, Shou-ching Jaminet, Bronislaw Pytowski, Julia H. Carter, Amit Aggarwal, Thompson Doman, Keyur Desai, Yunxia Sui, Yousef Al-Kofahi, Alberto Santamaria-Pang, Jee-yun Lee, Qi Xue, Damien Gerald, Anthony Fischl, Sudhakar Chintharlapalli, Diane Bodenmiller, Cynthia Jeffries, Larry Douglass, Christina Lowes, Christopher Sevinsky, Marguerita O'Mahony, Hilal Celikkaya, Julie Stewart, Seema Iyer, Beverly L. Falcon, Jiangang Liu, Mark T. Uhlik
These figures contain extensions of data that would not fit in the primary manuscript but are important for a complete understanding of the work. These include analysis of other data sets, correlations between genomic profiling our stromal subtyping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90482dc36b5d04c3119deb1b5d75d963
https://doi.org/10.1158/0008-5472.22413374.v1
https://doi.org/10.1158/0008-5472.22413374.v1
Autor:
Laura E. Benjamin, Harold F. Dvorak, Janice A. Nagy, Aejaz Nasir, Fiona Ginty, Shou-ching Jaminet, Bronislaw Pytowski, Julia H. Carter, Amit Aggarwal, Thompson Doman, Keyur Desai, Yunxia Sui, Yousef Al-Kofahi, Alberto Santamaria-Pang, Jee-yun Lee, Qi Xue, Damien Gerald, Anthony Fischl, Sudhakar Chintharlapalli, Diane Bodenmiller, Cynthia Jeffries, Larry Douglass, Christina Lowes, Christopher Sevinsky, Marguerita O'Mahony, Hilal Celikkaya, Julie Stewart, Seema Iyer, Beverly L. Falcon, Jiangang Liu, Mark T. Uhlik
This file contains details too lengthy to put in the primary manuscript file as well as methods for supplemental data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c7ba47360b9381a6bf5af261d51d70
https://doi.org/10.1158/0008-5472.22413371.v1
https://doi.org/10.1158/0008-5472.22413371.v1
Autor:
Louis F. Stancato, Aimee Bence Lin, Richard P. Beckmann, Jennifer Stephens, Julie Stewart, Beverly L. Falcon, Wayne Blosser, Michele Dowless, Alle B. VanWye, Caitlin D. Lowery
Supplemental methodology, specifically the in vitro cord formation assay and the enzyme-linked immunosorbent assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293c9b2e223ad6c5064eab5b446a0c96
https://doi.org/10.1158/1078-0432.22469084.v1
https://doi.org/10.1158/1078-0432.22469084.v1
Autor:
Laura E. Benjamin, Harold F. Dvorak, Janice A. Nagy, Aejaz Nasir, Fiona Ginty, Shou-ching Jaminet, Bronislaw Pytowski, Julia H. Carter, Amit Aggarwal, Thompson Doman, Keyur Desai, Yunxia Sui, Yousef Al-Kofahi, Alberto Santamaria-Pang, Jee-yun Lee, Qi Xue, Damien Gerald, Anthony Fischl, Sudhakar Chintharlapalli, Diane Bodenmiller, Cynthia Jeffries, Larry Douglass, Christina Lowes, Christopher Sevinsky, Marguerita O'Mahony, Hilal Celikkaya, Julie Stewart, Seema Iyer, Beverly L. Falcon, Jiangang Liu, Mark T. Uhlik
These are the figure legends for the supplemental figures and tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9768a910390204239cfa7e708e7b65
https://doi.org/10.1158/0008-5472.22413383.v1
https://doi.org/10.1158/0008-5472.22413383.v1
Autor:
Louis F. Stancato, Aimee Bence Lin, Richard P. Beckmann, Jennifer Stephens, Julie Stewart, Beverly L. Falcon, Wayne Blosser, Michele Dowless, Alle B. VanWye, Caitlin D. Lowery
Purpose: Checkpoint kinase 1 (CHK1) is a key regulator of the DNA damage response and a mediator of replication stress through modulation of replication fork licensing and activation of S and G2–M cell-cycle checkpoints. We evaluated prexasertib (L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace928a80491c543f787a72a8363ad6b
https://doi.org/10.1158/1078-0432.c.6527138.v1
https://doi.org/10.1158/1078-0432.c.6527138.v1
Autor:
Donald M. McDonald, David M. Epstein, Mark Miglarese, Philippe Depeille, Jennifer Fogarty, Jeyling Chou, Prafulla C. Gokhale, Sharon Barr, Beverly L. Falcon
Supplementary Figure 2 from Reduced VEGF Production, Angiogenesis, and Vascular Regrowth Contribute to the Antitumor Properties of Dual mTORC1/mTORC2 Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fde5fcd5be15ddb0f3e3c1e6e64e565
https://doi.org/10.1158/0008-5472.22391039
https://doi.org/10.1158/0008-5472.22391039