Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Beverly Giam"'
Publikováno v:
Nutrients, Vol 8, Iss 6, p 364 (2016)
Obesity related hypertension is a major risk factor for resistant hypertension. We do not completely understand the mechanism(s) underlying the development of obesity related hypertension which hinders the development of novel treatment strategies fo
Externí odkaz:
https://doaj.org/article/84a76b6c76854396ae3ddacbb01fce5c
Autor:
Matthew Snelson, Gavin W. Lambert, Assam El-Osta, Grant R Drummond, D. Donner, Melinda T. Coughlan, Helen Kiriazis, Aanthony Vinh, Duncan Horlock, Charles R. Mackay, Waled A. Shihata, Hamdi A. Jama, Beverly Giam, Tim D. Spector, Chad Johnson, Mark Ziemann, Xiao-Jun Du, April Fiedler, Kirill Tsyganov, Francine Z. Marques, David M. Kaye, Sarah E. Phillips, Amrita Vijay, Ana M. Valdes
Publikováno v:
Circulation. 141:1393-1403
Background: High blood pressure (BP) continues to be a major, poorly controlled but modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet poor in fiber is associated with prevalence of high BP. The impact of lac
Publikováno v:
Clinical Science. 133:2061-2067
The precise mechanisms underlying resistant hypertension remain elusive. Reduced nitric oxide (NO) bioavailability is frequently documented in chronic kidney disease, obesity, diabetes and advanced age, all of which are risk factors for resistant hyp
Autor:
Niwanthi W. Rajapakse, Sanjaya Kuruppu, Xiao-Jun Du, Beverly Giam, Haru Nomura, Po-Yin Chu, David M. Kaye, Sumia Essid, Helen Kiriazis
Publikováno v:
Clin Sci (Lond)
Heart failure (HF) is associated with impaired L-arginine transport. In the present study, we tested the hypothesis that augmented L-arginine transport prevents the loss of kidney function in HF. Renal function was assessed in wildtype mice (WT), tra
Autor:
Charles R. Mackay, Hamdi A. Jama, Kirill Tsyganov, Gavin W. Lambert, D. Donner, Helen Kiriazis, Grant R Drummond, Sarah E. Phillips, Chad Johnson, Francine Z. Marques, Duncan Horlock, Waled A. Shihata, Antony Vinh, April Fiedler, Mark Ziemann, David M. Kaye, Matthew Snelson, Sam El-Osta, Beverly Giam, Xiao-Jun Du
Publikováno v:
Hypertension. 74
Background: High fibre intake is associated with lower blood pressure (BP) in epidemiological and clinical studies. Prebiotic fibre resists digestion in the upper gastrointestinal tract and is fermented by gut microbiota in the intestine. The impact
Autor:
Xiao-Jun Du, Niwanthi W. Rajapakse, Sanjaya Kuruppu, Po-Yin Chu, Sumia Essid, David M. Kaye, Beverly Giam, Helen Kiriazis
Publikováno v:
The FASEB Journal. 33
Autor:
BEVERLY GIAM
Heart failure affects 1 in 20 Australians. Approximately half of these patients develop kidney failure and this is termed cardiorenal syndrome. There are currently no treatments for kidney dysfunction in patients with cardiorenal syndrome. The curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ecaed1db6e9aaba1fef1000a4bc65f6
Publikováno v:
Heart, Lung and Circulation. 25:874-880
Renal dysfunction and heart failure commonly co-exist; it is termed the cardiorenal syndrome (CRS). This combination of renal and cardiac impairment presents a substantial clinical challenge and is associated with adverse prognosis. The pathogenesis
Autor:
David M. Kaye, Po-Yin Chu, Beverly Giam, Sanjaya Kuruppu, Helen Kiriazis, Xiao-Jun Du, Niwanthi W. Rajapakse
Publikováno v:
The FASEB Journal. 32
Autor:
A. Ian Smith, April Fiedler, Sanjaya Kuruppu, Francine Z. Marques, Po-Yin Chu, Niwanthi W. Rajapakse, Beverly Giam, David M. Kaye, Helen Kiriazis, Duncan Horlock, Xiao-Jun Du
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Mechanisms underlying the renal pathology in cardiorenal syndrome (CRS) type 2 remain elusive. We hypothesised that renal glutathione deficiency is central to the development of CRS type 2. Glutathione precursor, N-acetylcysteine (NAC;40 mg/kg/day; 8