Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Beverly Galinski"'
Autor:
Radu Mihaila, Dipali Ruhela, Beverly Galinski, Ananda Card, Mark Cancilla, Timothy Shadel, Jing Kang, Samnang Tep, Jie Wei, R. Matthew Haas, Jeremy Caldwell, W. Michael Flanagan, Nelly Kuklin, Elena Cherkaev, Brandon Ason
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 367-377 (2019)
Drug combinations can improve the control of diseases involving redundant and highly regulated pathways. Validating a multi-target therapy early in drug development remains difficult. Small interfering RNAs (siRNAs) are routinely used to selectively
Externí odkaz:
https://doaj.org/article/c70715a5d4944003af0cba696f4c6468
Autor:
Radu Mihaila, Dipali Ruhela, Edward Keough, Elena Cherkaev, Silvia Chang, Beverly Galinski, René Bartz, Duncan Brown, Bonnie Howell, James J. Cunningham
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 246-255 (2017)
Lipid nanoparticles (LNPs) have been used to successfully deliver small interfering RNAs (siRNAs) to target cells in both preclinical and clinical studies and currently are the leading systems for in vivo delivery. Here, we propose the use of an ordi
Externí odkaz:
https://doaj.org/article/1bd07484f2df466c8fe8c61876a16515
Autor:
Brandon Ason, Samnang Tep, Jr. Harry R. Davis, Yiming Xu, Glen Tetzloff, Beverly Galinski, Ferdie Soriano, Natalya Dubinina, Lei Zhu, Alice Stefanni, Kenny K. Wong, Marija Tadin-Strapps, Steven R. Bartz, Brian Hubbard, Mollie Ranalletta, Alan B. Sachs, W. Michael Flanagan, Alison Strack, Nelly A. Kuklin
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 679-687 (2011)
Reducing circulating LDL-cholesterol (LDL-c) reduces the risk of cardiovascular disease in people with hypercholesterolemia. Current approaches to reduce circulating LDL-c include statins, which inhibit cholesterol synthesis, and ezetimibe, which blo
Externí odkaz:
https://doaj.org/article/5914edaf91c54338b6cfc9ad1842ba30
Autor:
R. Matthew Haas, Jing Kang, W. Michael Flanagan, Dipali Ruhela, Nelly A. Kuklin, Samnang Tep, Radu Mihaila, Elena Cherkaev, Jeremy Caldwell, Ananda Card, Timothy R. Shadel, Jie Wei, Brandon Ason, Beverly Galinski, Mark T. Cancilla
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 367-377 (2019)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Drug combinations can improve the control of diseases involving redundant and highly regulated pathways. Validating a multi-target therapy early in drug development remains difficult. Small interfering RNAs (siRNAs) are routinely used to selectively
Autor:
Edward Keough, René Bartz, Duncan Brown, Radu Mihaila, Beverly Galinski, Silvia Chang, Dipali Ruhela, Bonnie J. Howell, James J. Cunningham, Elena Cherkaev
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 246-255 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Lipid nanoparticles (LNPs) have been used to successfully deliver small interfering RNAs (siRNAs) to target cells in both preclinical and clinical studies and currently are the leading systems for in vivo delivery. Here, we propose the use of an ordi
Autor:
Kenny K. Wong, Brian K. Hubbard, Alison M. Strack, Beverly Galinski, Mollie Ranalletta, Lei Zhu, Harry R. Davis, Alice C. Stefanni, Natalya Dubinina, Glen Tetzloff, Samnang Tep, Ferdie Soriano, Yiming Xu, Marija Tadin-Strapps, Brandon Ason, Nelly A. Kuklin, Alan B. Sachs, Steven R. Bartz, W. Michael Flanagan
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 679-687 (2011)
Reducing circulating LDL-cholesterol (LDL-c) reduces the risk of cardiovascular disease in people with hypercholesterolemia. Current approaches to reduce circulating LDL-c include statins, which inhibit cholesterol synthesis, and ezetimibe, which blo
Autor:
Bret A. Hassel, Jayashree M. Paranjape, Steven Shah, Huiqin Nie, Robert H. Silverman, Aimin Zhou, Beverly Galinski
Publikováno v:
Journal of Interferon & Cytokine Research. 18:953-961
The biologic actions of interferons (IFNs) are complex and involve multiple biochemical mechanisms, including the 2-5A system, a regulated RNA decay pathway. The 2-5A system is implicated in the antipicornavirus activity of IFN and in the control of
Publikováno v:
The Journal of general virology. 69
The kinetics of synthesis of [35S]methionine-labelled respiratory syncytial virus-specific proteins were studied in CV-1 cells infected at high multiplicity. Immunoprecipitated viral proteins resolved by SDS-PAGE were quantified by scanning fluorogra