Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Beverly C. Delidow"'
Publikováno v:
Endocrine. 17:119-128
Control of the cell cycle is accomplished by sequentially activated cyclin-dependent kinases and the action of inhibitory proteins. We have shown that exposure of 235-1 rat pituitary tumor cells to dexamethasone (DEX) leads to a 50% reduction in grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e250d38903904b2b2549cd95d3bcd2
https://doi.org/10.1385/endo:17:2:119
https://doi.org/10.1385/endo:17:2:119
Publikováno v:
Journal of Cellular Physiology. 174:115-124
Rat 235-1 pituitary tumor cells are lactotrophs producing high levels of prolactin (PRL). Dexamethasone (Dex, 100 nM) inhibits PRL gene expression in 235-1 cells by 50%, while simultaneously decreasing cell replication and cell-cell aggregation. To d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7adff0951851cae02a77025f4dd7457b
https://doi.org/10.1002/(sici)1097-4652(199801)174:1<115::aid-jcp13>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199801)174:1<115::aid-jcp13>3.0.co
Publikováno v:
Biology of Reproduction. 47:428-435
The present series of experiments examined the effects of follicle-stimulating hormone (FSH) and insulin (IN) on granulosa cell (GC) proto-oncogene expression and DNA synthesis. In the first study, GCs were harvested from immature rat ovaries after 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef875cc262fa637e2e1f0d29eb15d18
https://doi.org/10.1095/biolreprod47.3.428
https://doi.org/10.1095/biolreprod47.3.428
Publikováno v:
Endocrinology. 126:2302-2306
Although gonadotropins stimulate ovarian granulosa cells to proliferate and differentiate into steroidogenic cells, little is known about the molecular mechanisms by which gonadotropins induce these fundamentally different responses. In this study th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71da24e0a1a2e1528dd95945adc98516
https://doi.org/10.1210/endo-126-5-2302
https://doi.org/10.1210/endo-126-5-2302
The melding of a technique for repeated rounds of DNA synthesis with the discovery of a thermostable DNA polymerase has given scientists the very powerful technique known as polymerase chain reaction (PCR). PCR is based on three simple steps required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792c67c00be204ad42baea0500a62e37
https://doi.org/10.1385/0-89603-244-2:1
https://doi.org/10.1385/0-89603-244-2:1
Autor:
Beverly C. Delidow
The transfection of expressible DNA into cell lines has allowed studies of gene expression and interaction that are often very difficult or impossible using the endogenous genes. The importance of this method is highlighted by the observation that, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea39cd90bc78a50dc32dc668c83d3556
https://doi.org/10.1385/0-89603-244-2:217
https://doi.org/10.1385/0-89603-244-2:217
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 6(8)
Rat pituitary acidophils consist of somatotropes (GH+/PRL-), lactotropes (GH-/PRL+), and lactosomatotropes (GH+/PRL+). Studies have indicated interconversion of these cell types in response to changing hormonal status. Representative tumor cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c992e87e18eb486ca0ff6dd2562fd50
https://pubmed.ncbi.nlm.nih.gov/1406705
https://pubmed.ncbi.nlm.nih.gov/1406705
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 6(8)
Previous observations that extracellular calcium (Ca2+) enhanced PRL mRNA levels posttranscriptionally in GH3 rat pituitary tumor cells were made using double-stranded transcription probes. The effects of Ca2+ and the Ca2+ ionophore, ionomycin, on PR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd012934461390b6d550b0e07b21b839
https://pubmed.ncbi.nlm.nih.gov/1406704
https://pubmed.ncbi.nlm.nih.gov/1406704
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 5(11)
Transforming growth factor-beta (TGF beta) is a member of a large family of growth factors, several of which regulate pituitary function. TGF beta has recently been reported to reduce PRL production by GH4 cells. We have examined the effect of TGF be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ab1d2ac7347ae36f2299e2088ddc28
https://pubmed.ncbi.nlm.nih.gov/1779973
https://pubmed.ncbi.nlm.nih.gov/1779973