Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bevan P. Gang"'
Autor:
Bevan P. Gang, Shakiba P. Baniasadi, Andrew Wakeham, Chiara Gorrini, Tak W. Mak, Yen-Ting Li, Wanda Y. Li, Christian Bassi, Sam D. Molyneux, Mona L. Gauthier, Zhenyue Hao, Edward E. Schmidt, David W. Cescon, Vuk Stambolic, Mathieu Lupien, Nadia M. Penrod
Publikováno v:
Proceedings of the National Academy of Sciences. 111:4472-4477
Mutations in the tumor suppressor BRCA1 predispose women to breast and ovarian cancers. The mechanism underlying the tissue-specific nature of BRCA1's tumor suppression is obscure. We previously showed that the antioxidant pathway regulated by the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b71a93560e2e871cc8a3c95267c747
https://doi.org/10.1073/pnas.1324136111
https://doi.org/10.1073/pnas.1324136111
Autor:
Niroshini M. Giles, Chun W. W. Yuen, Emilie M. F. Billaud, Gregory I. Giles, Sweta Kumari, Bevan P. Gang
Publikováno v:
Chemical Biology & Drug Design. 80:471-478
Nitric oxide is a small messenger molecule utilized by nature in cell signalling and the non-specific immune response. At present, nitric oxide releasing prodrugs cannot be efficiently targeted towards a specific body compartment, which restricts the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1812033b0222f1cf3ee5a2ed56e43ac2
https://doi.org/10.1111/j.1747-0285.2012.01420.x
https://doi.org/10.1111/j.1747-0285.2012.01420.x
Autor:
Stefan Vöö, Gregory I. Giles, Johannes Waltenberger, Bevan P. Gang, Michael J. Davies, Kevin D. Croft, Naomi Stanley, Nadina Stadler, Vladimir Vacata, Trevor A. Mori, Mat J.A.P. Daemen, Sylvia Heeneman
Publikováno v:
Atherosclerosis, 222(2), 512-518. Elsevier Ireland Ltd
Aims: Transition metal ions have been implicated in atherosclerosis. The goal of this study was to investigate whether metal ion levels were higher in people with diabetes, in view of their increased risk of aggravated atherosclerosis. Methods and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ea18b13ae0d089a1d8c635eb8bba07
https://doi.org/10.1016/j.atherosclerosis.2012.03.015
https://doi.org/10.1016/j.atherosclerosis.2012.03.015
Publikováno v:
Cancer Biology & Therapy
Deregulated metabolism is gaining recognition as a hallmark of cancer cells, and is being explored for therapeutic potential. The Warburg effect is a metabolic phenotype that occurs in 90% of tumors, where glycolysis is favored despite the presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6a710aafad04a222b02c189c8e88c2
https://pubmed.ncbi.nlm.nih.gov/25482950
https://pubmed.ncbi.nlm.nih.gov/25482950
Autor:
Niroshini M, Giles, Sweta, Kumari, Bevan P, Gang, Chun W W, Yuen, Emilie M F, Billaud, Gregory I, Giles
Publikováno v:
Chemical biologydrug design. 80(3)
Nitric oxide is a small messenger molecule utilized by nature in cell signalling and the non-specific immune response. At present, nitric oxide releasing prodrugs cannot be efficiently targeted towards a specific body compartment, which restricts the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72b6d530264d6dfc517a8aa321fc4512
https://pubmed.ncbi.nlm.nih.gov/22642531
https://pubmed.ncbi.nlm.nih.gov/22642531
Autor:
Cancer Metabolism, Melissa Rooke, Bevan P. Gang, Anneke C. Blackburn, Sheenu Mishra, Jane E. Dahlstrom
Publikováno v:
Cancer Research. 73:5421-5421
The Warburg effect occurs in 90% of tumours, where there is a high rate of glycolysis even in the presence of oxygen. This results in increased lactate production and reduced pyruvate oxidation. Dichloroacetate (DCA) is used clinically for congenital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33ca26b9e2bbb8a9e8a85198499b86d7
https://doi.org/10.1158/1538-7445.am2013-5421
https://doi.org/10.1158/1538-7445.am2013-5421