Trifluridine-tipiracil plus bevacizumab versus capecitabine plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer ineligible for intensive therapy (SOLSTICE): a randomised, open-label phase 3 study

Autor: Thierry André, Alfredo Falcone, Yaroslav Shparyk, Fedor Moiseenko, Eduardo Polo-Marques, Tibor Csöszi, Arinilda Campos-Bragagnoli, Gabor Liposits, Ewa Chmielowska, Paul Aubel, Lourdes Martín, Ronan Fougeray, Nadia Amellal, Mark P Saunders

Publikováno v: André, T, Falcone, A, Shparyk, Y, Moiseenko, F, Polo-Marques, E, Csöszi, T, Campos-Bragagnoli, A, Liposits, G, Chmielowska, E, Aubel, P, Martín, L, Fougeray, R, Amellal, N & Saunders, M P 2023, ' Trifluridine–tipiracil plus bevacizumab versus capecitabine plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer ineligible for intensive therapy (SOLSTICE) : a randomised, open-label phase 3 study ', The Lancet. Gastroenterology & hepatology, vol. 8, no. 2, pp. 133-144 . https://doi.org/10.1016/S2468-1253(22)00334-X

Background: Trifluridine–tipiracil plus bevacizumab has shown efficacy in previous phase 2 studies including patients with unresectable metastatic colorectal cancer. We aimed to investigate first-line trifluridine–tipiracil plus bevacizumab versu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cadad6db1d3357344ba4d26926f5a7a
https://pubmed.ncbi.nlm.nih.gov/36470291

The area of fixation covaries with short-term changes in visual acuity after anti-vascular endothelial growth factor treatment in patients with diabetic macular oedema

Autor: Toke Bek, Dorte Ancher Larsen, Nanna Stæhr Jakobsen

Publikováno v: Jakobsen, N S, Larsen, D A & Bek, T 2018, ' The area of fixation covaries with short-term changes in visual acuity after anti-vascular endothelial growth factor treatment in patients with diabetic macular oedema ', Acta Ophthalmologica, vol. 96, no. 7, pp. 744-748 . https://doi.org/10.1111/aos.13773

PURPOSE: Diabetic maculopathy can be treated with intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors. However, the therapy is not effective in all patients, and it would be desirable to have parameters for differentiating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6aeeb6f9d5ebbd6c1dd56955ddff4be
https://doi.org/10.1111/aos.13773

A rare case of metastatic atypical meningioma that highlights the shortcomings of treatment options at present.

Autor: Wrange, Erik Kristian Maurice¹ (AUTHOR) erik_wrange@yahoo.se, Harders, Stefan Markus Walbom² (AUTHOR)

Publikováno v: Acta Radiologica Open. Jul2022, Vol. 11 Issue 7, p1-5. 5p.

Swept-source optical coherence tomography findings in premature children with a history of retinopathy of prematurity at 5 years of age

Autor: Gokhan Celik, Murat Gunay, Osman Kizilay

Publikováno v: Arquivos Brasileiros de Oftalmologia, Vol 83, Iss 6, Pp 490-496 (2021)
Arquivos Brasileiros de Oftalmologia v.83 n.6 2020
Arquivos brasileiros de oftalmologia
Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO

Purpose: To compare central foveal thickness, retinal nerve fiber layer thickness, and subfoveal choroidal thickness using swept-source optical coherence tomography in premature children with a history of treated retinopathy of prematurity (either wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c45bece797c8c50b7ea89eb8d2292be6
https://pubmed.ncbi.nlm.nih.gov/33470276

Vascular Endothelial Growth Factor Antagonists as Anticancer Agents.

Autor: Hasan, Jurjees¹ Jurgees.Hasan@christie-tr.nwest.nhs.uk, Jayson, Gordon C.¹

Publikováno v: American Journal of Cancer. Jul2004, Vol. 3 Issue 4, p229-245. 17p. 1 Chart.