Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Beutline Malgija"'
2
Akademický článek
Mining of transcriptome identifies CD109 and LRP12 as possible biomarkers and deregulation mechanism of T cell receptor pathway in Acute Myeloid Leukemia
Autor: EbyNesar StellaGlory Deepak Shyl, Beutline Malgija, Appadurai Muthamil Iniyan, Ramasamy Mahendran, Samuel Gnana Prakash Vincent
Publikováno v: Heliyon, Vol 8, Iss 10, Pp e11123- (2022)
Acute Myeloid Leukemia (AML) is a heterogeneous disease with highest mortality compared to other types of leukemia. There is a need to find the gene abnormalities and mechanisms behind them due to their heterogenic nature. The present study is aimed
Externí odkaz: https://doaj.org/article/262ab8c2738348548f738ee0def4bd7c
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3
Akademický článek
Computational analysis of sequential and structural variations in stromelysins as an insight towards matrix metalloproteinase research
Autor: Beutline Malgija, Host Antony David Rajendran, Uma Maheswari, Nivetha Sarah Ebenezer, Joyce Priyakumari, Shanmughavel Piramanayagam
Publikováno v: Informatics in Medicine Unlocked, Vol 11, Iss , Pp 28-35 (2018)
Matrix metalloproteinases are zinc-dependent protein and peptide hydrolases. They are broadly involved in metabolic regulation through both extensive protein degradation and selective peptide-bond hydrolysis. Stromelysins belong to this group of prot
Externí odkaz: https://doaj.org/article/09ea769575484797b3619f3cf3fbc9e0
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4
Akademický článek
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7
In Silico prediction and Comparative Modeling of proteins in Creeping Fig (Ficus pumila) plant
Autor: M. Beutline Malgija, P. Revathi, K. Nirubama, G. Thamotharan
Publikováno v: Journal of University of Shanghai for Science and Technology. 23:898-905
In the present study, the Ficus pumila have taken to analyze the proteins by their preliminary characters from the database and predicted vital role of different sequences. The F. pumila (Creeping fig) is a prostrate/climbing shrub, experiments prove
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31e7f36e7c5f0c105ec4a8c1f3d9209a
https://doi.org/10.51201/jusst/21/08479
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8
Insight into designing of 2-pyridone derivatives for COVID-19 drug discovery - A computational study
Autor: Joseph George Samuel, Beutline Malgija, Cheriyan Ebenezer, Rajadurai Vijay Solomon
Publikováno v: Structural chemistry.
Presently, the prime global focus is on SARS-CoV-2, as no fully established, licensed medicine has been found thus far, in spite of the existence of various reports and administration of partially proven certain class of natural products. However, in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecc6182c787389516e8b88e54432972
https://pubmed.ncbi.nlm.nih.gov/36320317
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9
Mutation in MCL1 predicted loop to helix structural transition stabilizes MCL1-Bax binding interaction favoring cancer cell survival
Autor: Eby‐nesar Stella‐glory Deepak Shyl, Beutline Malgija, Appadurai Muthamil Iniyan, Samuel Gnana Prakash Vincent
Publikováno v: ProteinsREFERENCES. 90(9)
Myeloid cell leukemia-1 (MCL1), an anti-apoptotic BCL-2 family protein plays a major role in the control of apoptosis as the regulator of mitochondrial permeability which is deregulated in various solid and hematological malignancies. Interaction of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb12cf596a753261c84f6bfc4c2a24b
https://pubmed.ncbi.nlm.nih.gov/35429048
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