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Autor:
Chteinberg, Emil, Sauer, Christopher Martin, Rennspiess, Dorit, Beumers, Lukas, Schiffelers, Lisa, Eben, Jonathan, Haugg, Anke, Winnepenninckx, Véronique, Kurz, Anna Kordelia, Speel, Ernst-Jan, Zenke, Martin, zur Hausen, Axel
Publikováno v:
In Neoplasia December 2018 20(12):1227-1235
Autor:
Beumers, Lukas
Breast cancer is the most common malignancy in women worldwide and roughly two-thirds of breast tumors are characterized by estrogen receptor (ER) α expression allowing for a targeted treatment approach by suppressing estrogen signaling. Clinically,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6448319e6fe7280343d23036b349c5bb
Autor:
Kaminska, Kamila, Akrap, Nina, Staaf, Johan, Alves, Carla L., Ehinger, Anna, Ebbesson, Anna, Hedenfalk, Ingrid, Beumers, Lukas, Veerla, Srinivas, Harbst, Katja, Ehmsen, Sidse, Borgquist, Signe, Borg, Åke, Pérez-Fidalgo, Alejandro, Ditzel, Henrik J., Bosch, Ana, Honeth, Gabriella
Additional file 4. Figure showing quantification of western blotting band intensities. Quantification of western blotting band intensities presented in Fig. 1c, 2a-c and 5a as well as Additional Files 3F, 5A-C and 9B. Combined data from at least thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d2f7bfa77881be396823ad34868ed9
Autor:
Kaminska, Kamila, Akrap, Nina, Staaf, Johan, Alves, Carla L., Ehinger, Anna, Ebbesson, Anna, Hedenfalk, Ingrid, Beumers, Lukas, Veerla, Srinivas, Harbst, Katja, Ehmsen, Sidse, Borgquist, Signe, Borg, Åke, Pérez-Fidalgo, Alejandro, Ditzel, Henrik J., Bosch, Ana, Honeth, Gabriella
Additional file 5. Figure showing fulvestrant-withdrawal data for the ZR-75-1, T47D and EFM-19 models. Fulvestrant dose-response curves (5 nM to 10 μM) and western blotting for ERα expression in fulvestrant-resistant (-FR) ZR-75-1 (A), T47D (B) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac51c72f47e9c4a8d24117db9dae8769
Autor:
Kaminska, Kamila, Akrap, Nina, Staaf, Johan, Alves, Carla L., Ehinger, Anna, Ebbesson, Anna, Hedenfalk, Ingrid, Beumers, Lukas, Veerla, Srinivas, Harbst, Katja, Ehmsen, Sidse, Borgquist, Signe, Borg, Åke, Pérez-Fidalgo, Alejandro, Ditzel, Henrik J., Bosch, Ana, Honeth, Gabriella
Additional file 2. Table showing patient characteristics for patient samples pre and post fulvestrant treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fc499a8f3cdcebfbe6e5ecf547a299
Autor:
Kaminska, Kamila, Akrap, Nina, Staaf, Johan, Alves, Carla L., Ehinger, Anna, Ebbesson, Anna, Hedenfalk, Ingrid, Beumers, Lukas, Veerla, Srinivas, Harbst, Katja, Ehmsen, Sidse, Borgquist, Signe, Borg, Åke, Pérez-Fidalgo, Alejandro, Ditzel, Henrik J., Bosch, Ana, Honeth, Gabriella
Additional file 10. Figure showing survival analyses of cyclin E1 and E2 in fulvestrant-treated metastatic breast cancer patients. Kaplan-Meier plot for overall survival (OS) in cyclin E2 low versus high expression in ER+ metastatic breast cancer pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a002ef3b0a1820eb78d11a4be6cdd4
Autor:
Kaminska, Kamila, Akrap, Nina, Staaf, Johan, Alves, Carla L., Ehinger, Anna, Ebbesson, Anna, Hedenfalk, Ingrid, Beumers, Lukas, Veerla, Srinivas, Harbst, Katja, Ehmsen, Sidse, Borgquist, Signe, Borg, Åke, Pérez-Fidalgo, Alejandro, Ditzel, Henrik J., Bosch, Ana, Honeth, Gabriella
Additional file 7. Figure showing BAF and LogR files for copy number data. B allele frequency (BAF) and LogR genome-wide plots for SNP profiled cell line data presented in Fig. 4a. Chromosomes are ordered along the x-axis from 1 (left) to Y (right).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795f6ba2c07f29aabf8bc84de141e96b
Autor:
Kaminska, Kamila, Akrap, Nina, Staaf, Johan, Alves, Carla L., Ehinger, Anna, Ebbesson, Anna, Hedenfalk, Ingrid, Beumers, Lukas, Veerla, Srinivas, Harbst, Katja, Ehmsen, Sidse, Borgquist, Signe, Borg, Åke, Pérez-Fidalgo, Alejandro, Ditzel, Henrik J., Bosch, Ana, Honeth, Gabriella
Additional file 3. Figure showing that fulvestrant-resistant cells proliferate in the presence of fulvestrant and downregulate ER signaling. A) Time in weeks for each parental cell line to develop resistance to fulvestrant, from initial 100 pM dose u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461173833b6e71bb316b6e6ef4285732
Autor:
Kaminska, Kamila, Akrap, Nina, Staaf, Johan, Alves, Carla L., Ehinger, Anna, Ebbesson, Anna, Hedenfalk, Ingrid, Beumers, Lukas, Veerla, Srinivas, Harbst, Katja, Ehmsen, Sidse, Borgquist, Signe, Borg, Åke, Pérez-Fidalgo, Alejandro, Ditzel, Henrik J., Bosch, Ana, Honeth, Gabriella
Additional file 8. Table showing common processes enriched in fulvestrant-resistant cells identified by DAVID bioinformatics tool. DAVID functional categories and gene ontology (GO) functions as well as KEGG and Biocarta pathways for genes downregula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a86877c06b9beb9e0119deac168523b