Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Betty Yuen‐Kwan Law"'
Autor:
Liqun Qu, Yong Tang, Jianhui Wu, Xiaoyun Yun, Hang Hong Lo, Linlin Song, Xingxia Wang, Huimiao Wang, Ruilong Zhang, Menghan Liu, Cairen Wang, Jerome P. L. Ng, Xianjun Fu, Io Nam Wong, Vincent Kam Wai Wong, Betty Yuen Kwan Law
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Background Activating the ubiquitin-proteasome system to dismantle disease- related proteins such as tau, β-amyloid, APP, and α-synuclein is an important focus in the research of neurodegenerative proteinopathy. By analyzing the serum RNA
Externí odkaz:
https://doaj.org/article/91c8b4410c6e4338b71bd87ae6921272
Autor:
Xiaogang Zhou, Jing Wang, Lu Yu, Gan Qiao, Dalian Qin, Betty Yuen-Kwan Law, Fang Ren, Jianming Wu, Anguo Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3327-3361 (2024)
Mitophagy, essential for mitochondrial health, selectively degrades damaged mitochondria. It is intricately linked to the cGAS–STING pathway, which is crucial for innate immunity. This pathway responds to mitochondrial DNA and is associated with ce
Externí odkaz:
https://doaj.org/article/1471e72ae72c4e8f9f45471e7ca494cb
Autor:
Xing Xia Wang, Xiang Ji, Jing Lin, Io Nam Wong, Hang Hong Lo, Jian Wang, Liqun Qu, Vincent Kam Wai Wong, Sookja Kim Chung, Betty Yuen Kwan Law
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107395- (2024)
G protein-coupled receptors (GPCRs), widely expressed in the human central nervous system (CNS), perform numerous physiological functions and play a significant role in the pathogenesis of diseases. Consequently, identifying key therapeutic GPCRs tar
Externí odkaz:
https://doaj.org/article/5b0dcaf1407c4b758fbae49856466d95
Autor:
Bo Qin, Shi-jie Fu, Xiong-fei Xu, Jiu-jie Yang, Yuping Wang, Lin-na Wang, Bai-xiong Huang, Jing Zhong, Wan-yu Wu, Heng-ao Lu, Betty Yuen Kwan Law, Nick Wang, Io Nam Wong, Vincent Kam Wai Wong
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107349- (2024)
In future regenerative medicine, far-infrared radiation (FIR) may be an essential component of optical therapy. Many studies have confirmed or validated the efficacy and safety of FIR in various diseases, benefiting from new insights into FIR mechani
Externí odkaz:
https://doaj.org/article/4eebceedf7174b5c9e20ffe6b7742dbc
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-20 (2024)
Abstract Diabetic cardiomyopathy (DCM) is a major contributor to mortality in diabetic patients, characterized by a multifaceted pathogenesis and limited therapeutic options. While lactate, a byproduct of glycolysis, is known to be significantly elev
Externí odkaz:
https://doaj.org/article/4eacbb6a4f924cb48db92829cff15900
Autor:
Yong Tang, Jing Wei, Xiao-Fang Wang, Tao Long, Xiaohong Xiang, Liqun Qu, Xingxia Wang, Chonglin Yu, Xingli Xiao, Xueyuan Hu, Jing Zeng, Qin Xu, Anguo Wu, Jianming Wu, Dalian Qin, Xiaogang Zhou, Betty Yuen-Kwan Law
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 11, Pp 2467-2479 (2024)
Amyloid-beta-induced neuronal cell death contributes to cognitive decline in Alzheimer’s disease. Citri Reticulatae Semen has diverse beneficial effects on neurodegenerative diseases, including Parkinson’s and Huntington’s diseases, however, th
Externí odkaz:
https://doaj.org/article/47fd4ae8f9814548af6e3edf2a0cae7a
Autor:
Congling Qiu, Joyce Tsz Wai Chan, David Wei Zhang, Io Nam Wong, Yaling Zeng, Betty Yuen Kwan Law, Simon Wing Fai Mok, Ivo Ricardo De Seabra Rodrigues Dias, Wenfeng Liu, Liang Liu, Vincent Kam Wai Wong
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2252-2255 (2023)
Externí odkaz:
https://doaj.org/article/5d7f0cc244d6412cbdeec013857b1e51
Autor:
Mengyu Wang, Liqun Qu, Xinying Du, Peng Song, Jerome P. L. Ng, Vincent Kam Wai Wong, Betty Yuen Kwan Law, Xianjun Fu
Publikováno v:
Metabolites, Vol 14, Iss 9, p 490 (2024)
Metabolic reprogramming is a critical pathogenesis of colorectal cancer (CRC), referring to metabolic disorders that cancer cells make in response to the stimulating pressure. Metabolic reprogramming induces changes in genetic material and promotes C
Externí odkaz:
https://doaj.org/article/62eba4b9f973491aab7391d8dbc9092a
Age-related self-DNA accumulation may accelerate arthritis in rats and in human rheumatoid arthritis
Autor:
Wei-Dan Luo, Yu-Ping Wang, Jun Lv, Yong Liu, Yuan-Qing Qu, Xiong-Fei Xu, Li-Jun Yang, Zi-Cong Lin, Lin-Na Wang, Rui-Hong Chen, Jiu-Jie Yang, Ya-Ling Zeng, Rui-Long Zhang, Bai-Xiong Huang, Xiao-Yun Yun, Xuan-Ying Wang, Lin-Lin Song, Jian-Hui Wu, Xing-Xia Wang, Xi Chen, Wei Zhang, Hui-Miao Wang, Li-Qun Qu, Meng-Han Liu, Liang Liu, Betty Yuen Kwan Law, Vincent Kam Wai Wong
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The incidence of rheumatoid arthritis (RA) is increasing with age. DNA fragments is known to accumulate in certain autoimmune diseases, but the mechanistic relationship among ageing, DNA fragments and RA pathogenesis remain unexplored. Here
Externí odkaz:
https://doaj.org/article/22b49d652b674e008a0d162be949e0a8
Autor:
Hui Miao Wang, Hong Juan Lai, An Guo Wu, Yong Tang, Lin Lin Song, Hang Hong Lo, Io Nam Wong, Vincent Kam Wai Wong, Betty Yuen Kwan Law
Publikováno v:
Journal of Functional Foods, Vol 112, Iss , Pp 105962- (2024)
Background: A phytochemical 5-demethylnobiletin from Citrus reticulata Blanco has a broad spectrum of pharmacological effects on anti-inflammatory, cardiovascular and neuroprotective effects, however, its in vivo effect on depigmentation remains unkn
Externí odkaz:
https://doaj.org/article/313218f2eeef44a58b225aef98faab60