Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Betty P. Tsao"'
Autor:
Marice K. McCrorey, Kennedy P. Hawkins, Marharyta Semenikhina, Matthew Bernstein, Ryan Lacey, C. Alex Colvert, Jim C. Oates, Betty P. Tsao, Kristine Y. DeLeon‐Pennell, Oleg Palygin, Melissa A. Cunningham, Justin P. Van Beusecum
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 12, Pp 891-899 (2024)
Objective Systemic lupus erythematosus (SLE) affects nine women to every man worldwide, and these patients are at greater risk for cardiovascular disease (CVD) morbidity and mortality. Clinical studies have demonstrated that patients with SLE are mor
Externí odkaz:
https://doaj.org/article/a843c410e99d4066b65041dc2120e74f
Autor:
Jim C Oates, Qing Sun, Joel M Guthridge, Judith A James, Lei Wang, Diane L Kamen, Fang Wang, Miaojia Zhang, Gary S Gilkeson, Deborah K McCurdy, Lingxiao Xu, Wenfeng Tan, Jian Zhao, Ting Liu, Bevra H Hahn, Betty P Tsao, R Hal Scofield, Yun Deng, Prithvi Raj, Edward K Wakeland, Linyu Geng, Xue Xu, Yunjuan Wu, Jingfeng Zhu, Alexander Awgulewitsch
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/29d520723cca4e048732eacb99f2b0c0
Autor:
Prithvi Raj, Ran Song, Honglin Zhu, Linley Riediger, Dong-Jae Jun, Chaoying Liang, Carlos Arana, Bo Zhang, Yajing Gao, Benjamin E. Wakeland, Igor Dozmorov, Jinchun Zhou, Jennifer A. Kelly, Bernard R. Lauwerys, Joel M. Guthridge, Nancy J. Olsen, Swapan K. Nath, Chandrashekhar Pasare, Nicolai van Oers, Gary Gilkeson, Betty P. Tsao, Patrick M. Gaffney, Peter K. Gregersen, Judith A. James, Xiaoxia Zuo, David R. Karp, Quan-Zhen Li, Edward K. Wakeland
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-26 (2020)
Abstract Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease characterized by the development of anti-nuclear antibodies. Susceptibility to SLE is multifactorial, with a combination of genetic and environmen
Externí odkaz:
https://doaj.org/article/e20309c0541c416c958c9d60fca43e2b
Autor:
Yantong Zhu, Xiaojun Tang, Yang Xu, Si Wu, Weilin Liu, Linyu Geng, Xiaolei Ma, Betty P. Tsao, Xuebing Feng, Lingyun Sun
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus (SLE) is characterized by the production of pathogenic autoantibodies. Ribonuclease A family member 2 (RNase2) is known to have antiviral activity and immunomodulatory function. Although RNASE2 level has been reported to
Externí odkaz:
https://doaj.org/article/195d4b3c20854d00ba75d8ae3893db7e
Autor:
Gary S Gilkeson, Jian Zhao, Betty P Tsao, Phillip Ruiz, Yun Deng, Quan-Zhen Li, Diane Kamen, Ivan Molano, Xue Xu, Lin-Yu Geng, Ling-Xiao Xu, Xue-Bing Feng, Miao-Jia Zhang, Wen-Feng Tan, Ling-Yun Sun
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/ee78d9a52224417785b49e9324fdae82
Autor:
Zhenwu Luo, Alexander V. Alekseyenko, Elizabeth Ogunrinde, Min Li, Quan-Zhen Li, Lei Huang, Betty P. Tsao, Diane L. Kamen, Jim C. Oates, Zihai Li, Gary S. Gilkeson, Wei Jiang
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Blood microbiome is important to investigate microbial-host interactions and the effects on systemic immune perturbations. However, this effort has met with major challenges due to low microbial biomass and background artifacts. In the current study,
Externí odkaz:
https://doaj.org/article/89d071aa6a354071b293ab845a612355
Autor:
Linyu Geng, Xiaojun Tang, Shiying Wang, Yue Sun, Dandan Wang, Betty P. Tsao, Xuebing Feng, Lingyun Sun
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic lupus erythematosus (SLE) patients exist an imbalance between regulatory T (Treg) and T helper 17 cells (Th17), which might be contributed by defective immune regulation of bone marrow derived mesenchymal stem cells (BM-MSCs) from SLE patien
Externí odkaz:
https://doaj.org/article/e6b97d576b68470fa3f9faa1a72cce7b
Autor:
Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hyp
Externí odkaz:
https://doaj.org/article/a68227bc3ba0457486591e4743061bf9
Autor:
Lingxiao Xu, Jian Zhao, Qing Sun, Xue Xu, Lei Wang, Ting Liu, Yunjuan Wu, Jingfeng Zhu, Linyu Geng, Yun Deng, Alexander Awgulewitsch, Diane L Kamen, Jim C Oates, Prithvi Raj, Edward K Wakeland, R Hal Scofield, Joel M Guthridge, Judith A James, Bevra H Hahn, Deborah K McCurdy, Fang Wang, Miaojia Zhang, Wenfeng Tan, Gary S Gilkeson, Betty P Tsao
Publikováno v:
Annals of the Rheumatic Diseases. 81:1712-1721
ObjectivesFamilies that contain multiple siblings affected with childhood onset of systemic lupus erythematosus (SLE) likely have strong genetic predispositions. We performed whole exome sequencing (WES) to identify familial rare risk variants and to
Autor:
Julio E Molineros, Loren L Looger, Kwangwoo Kim, Yukinori Okada, Chikashi Terao, Celi Sun, Xu-Jie Zhou, Prithvi Raj, Yuta Kochi, Akari Suzuki, Shuji Akizuki, Shuichiro Nakabo, So-Young Bang, Hye-Soon Lee, Young Mo Kang, Chang-Hee Suh, Won Tae Chung, Yong-Beom Park, Jung-Yoon Choe, Seung-Cheol Shim, Shin-Seok Lee, Xiaoxia Zuo, Kazuhiko Yamamoto, Quan-Zhen Li, Nan Shen, Lauren L Porter, John B Harley, Kek Heng Chua, Hong Zhang, Edward K Wakeland, Betty P Tsao, Sang-Cheol Bae, Swapan K Nath
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008092 (2019)
Human leukocyte antigen (HLA) is a key genetic factor conferring risk of systemic lupus erythematosus (SLE), but precise independent localization of HLA effects is extremely challenging. As a result, the contribution of specific HLA alleles and amino
Externí odkaz:
https://doaj.org/article/d7d6c5952b52494fad910b4f86bf3dd4