Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Betty I. Sasyniuk"'
Autor:
Teresa Kuś, Sylvain Brunet, Chantal Pharand, René Cardinal, Katayoun Derakhchan, Betty I. Sasyniuk, Didier Klug
Publikováno v:
Cardiovascular research. 38(3)
Objective : Polymorphic ventricular tachycardias (PVT) occur spontaneously in canine hearts under the combination of d-sotalol (S), bradycardia and phenylephrine (PE). We investigated the hypotheses that: (1) the activation patterns of the initial PV
Publikováno v:
Annals of Emergency Medicine. 15:1052-1059
Overdose with amitriptyline and other tricyclic antidepressants can result in ventricular conduction abnormalities as well as severe ventricular arrhythmias. The arrhythmogenic effects of these compounds may be attributed to their direct local anesth
Autor:
Betty I. Sasyniuk, Teresa Kus
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 56:326-331
We compared the effects of a therapeutic concentration of disopyramide with those of quinidine and lidocaine on the action potential characteristics and on the steady-state relationship between membrane potential and the maximum rate of rise of the a
Publikováno v:
The American Journal of Cardiology. 64:J29-J32
QTU prolongation and polymorphic ventricular rachycardia “torsades de pointes” have occurred in association with electrolyte abnormalities and during therapy with class IA and III antiarrhythmic drugs. Several recent studies have suggested that t
Publikováno v:
Pediatric Clinics of North America. 33:583-602
This article focuses on some of the problems encountered with two of the drugs currently given to newborns.
Autor:
Betty I. Sasyniuk
Publikováno v:
The American Journal of Cardiology. 54:A1-A6
Arrhythmias can result from abnormal impulse initiation or conduction. Abnormal initiation results from either automaticity or triggered activity. Enhanced automaticity may be due to a normal automatic mechanism (a normal property of the sinus node a
Autor:
Stanley Nattel, Betty I. Sasyniuk
Publikováno v:
Trends in Pharmacological Sciences. 3:297-300
Since its introduction in the 191%. lidocaine has become the drug of tint choice for the emergency treatment of veb tricular arrhythmias. Much information has bren obtained about the elrczrophysiologt. cat actions of lidocaine. but the mechaa isms by
Autor:
Carlos Mendez, Betty I. Sasyniuk
Publikováno v:
Circulation Research. 28:3-15
In isolated canine papillary muscle-false tendon preparations it was possible by selecting the pattern of stimulation to obtain conduction block within the peripheral distribution of the Purkinje network. Action potentials recorded just proximal to t
Autor:
Teresa Kus, Betty I. Sasyniuk
Publikováno v:
Circulation research. 37(6)
Disopyramide phosphate is a new antiarrhythmic drug that has been shown to possess significant antiarrhythmic effects in animals and man. In the present investigation, the effects of 2, 5, and 10 mug/ml of disopyramide phosphate were studied on the e
Autor:
Matthew A. Flemming, Betty I. Sasyniuk
Publikováno v:
Canadian journal of physiology and pharmacology. 67(7)
The voltage- and frequency-dependent blocking actions of disopyramide were assessed in canine Purkinje fibers within the framework of concentrations, membrane potentials, and heart rates which have relevance to the therapeutic actions of this drug. [