Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Betty Hebecker"'
Autor:
Stefanie Allert, Toni M. Förster, Carl-Magnus Svensson, Jonathan P. Richardson, Tony Pawlik, Betty Hebecker, Sven Rudolphi, Marc Juraschitz, Martin Schaller, Mariana Blagojevic, Joachim Morschhäuser, Marc Thilo Figge, Ilse D. Jacobsen, Julian R. Naglik, Lydia Kasper, Selene Mogavero, Bernhard Hube
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, th
Externí odkaz:
https://doaj.org/article/8caa6f60252d4a35989645f46583594a
Autor:
Daniela Mailänder-Sánchez, Christina Braunsdorf, Christian Grumaz, Christoph Müller, Stefan Lorenz, Philip Stevens, Jeanette Wagener, Betty Hebecker, Bernhard Hube, Franz Bracher, Kai Sohn, Martin Schaller
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0184438 (2017)
Candida albicans is an inhabitant of mucosal surfaces in healthy individuals but also the most common cause of fungal nosocomial blood stream infections, associated with high morbidity and mortality. As such life-threatening infections often dissemin
Externí odkaz:
https://doaj.org/article/60d303a72f7444d78c4b52eb26e0861f
Publikováno v:
European Journal of Immunology. 48:1826-1837
Inflammatory bowel diseases (IBD) are a multifactorial disorder. Our understanding of the role of bacteria in the pathogenesis of IBD has increased substantially; however, only scarce data exist regarding the role of commensal fungi in maintaining in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fce87669e5d13505fb9d0223b94665
https://doi.org/10.1002/eji.201847586
https://doi.org/10.1002/eji.201847586
Autor:
Simona Ioana Iancu, Shirley X. Tang, Manohursingh Runglall, Antje Häder, Julian R. Naglik, Betty Hebecker, Toni M. Förster, Duncan Wilson, Robert T. Wheeler, Remi L. Gratacap, Jon Robbins, Oliver Bader, Sarah Höfs, Ernesto Cota, Gema Vizcay, Jonathan P. Richardson, Nessim Kichik, Mariana Blagojevic, Ting Luo, Olaf Kniemeyer, Julia Wernecke, Bernhard Hube, Thomas Krüger, David L. Moyes, Selene Mogavero, Celia Murciano, Lydia Kasper, Oliver Kurzai, Thomas Gutsmann, Selvam Thavaraj
Publikováno v:
Nature 532(7597), 64-68 (2016). doi:10.1038/nature17625
Nature
Moyes, D L, Wilson, D, Richardson, J P, Mogavero, S, Tang, S X, Wernecke, J, Hofs, S, Gratacap, R L, Robbins, J, Runglall, M, Murciano, C, Blagojevic, M, Thavaraj, S, Forster, T M, Hebecker, B, Kasper, L, Vizcay-Barrena, G, Iancu, S I, Kichik, N, Hader, A, Kurzai, O, Luo, T, Kruger, T, Kniemeyer, O, Cota, E, Bader, O, Bader, O, Wheeler, R T, Gutsmann, T, Hube, B & Naglik, J R 2016, ' Candidalysin is a fungal peptide toxin critical for mucosal infection ', NATURE, vol. 532, no. 7597, pp. 64-68 . https://doi.org/10.1038/nature17625
Nature
Moyes, D L, Wilson, D, Richardson, J P, Mogavero, S, Tang, S X, Wernecke, J, Hofs, S, Gratacap, R L, Robbins, J, Runglall, M, Murciano, C, Blagojevic, M, Thavaraj, S, Forster, T M, Hebecker, B, Kasper, L, Vizcay-Barrena, G, Iancu, S I, Kichik, N, Hader, A, Kurzai, O, Luo, T, Kruger, T, Kniemeyer, O, Cota, E, Bader, O, Bader, O, Wheeler, R T, Gutsmann, T, Hube, B & Naglik, J R 2016, ' Candidalysin is a fungal peptide toxin critical for mucosal infection ', NATURE, vol. 532, no. 7597, pp. 64-68 . https://doi.org/10.1038/nature17625
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial pathogens which disrupt epithelial barrier function, damage cells and activate or modulate host immune responses. Such toxins have not been identified previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3ac8fab981d08688d3eced11330ffc
https://doi.org/10.1038/nature17625
https://doi.org/10.1038/nature17625
Autor:
Marc Juraschitz, Bernhard Hube, Jonathan P. Richardson, Julian R. Naglik, Betty Hebecker, Marc Thilo Figge, Stefanie Allert, Carl-Magnus Svensson, Tony Pawlik, Toni M. Förster, Lydia Kasper, Mariana Blagojevic, Selene Mogavero, Joachim Morschhäuser, Martin Schaller, Ilse D. Jacobsen, Sven Rudolphi
Publikováno v:
mBio, Vol 9, Iss 3, p e00915-18 (2018)
mBio, Vol 9, Iss 3 (2018)
Allert, S, Förster, T M, Svensson, C-M, Richardson, J P, Pawlik, T, Hebecker, B, Rudolphi, S, Juraschitz, M, Schaller, M, Blagojevic, M, Morschhäuser, J, Figge, M T, Jacobsen, I D, Naglik, J R, Kasper, L, Mogavero, S & Hube, B 2018, ' Candida albicans-induced epithelial damage mediates translocation through intestinal barriers ', Mbio, vol. 9, no. 3, e00915-18 . https://doi.org/10.1128/mBio.00915-18
mBio
mBio, Vol 9, Iss 3 (2018)
Allert, S, Förster, T M, Svensson, C-M, Richardson, J P, Pawlik, T, Hebecker, B, Rudolphi, S, Juraschitz, M, Schaller, M, Blagojevic, M, Morschhäuser, J, Figge, M T, Jacobsen, I D, Naglik, J R, Kasper, L, Mogavero, S & Hube, B 2018, ' Candida albicans-induced epithelial damage mediates translocation through intestinal barriers ', Mbio, vol. 9, no. 3, e00915-18 . https://doi.org/10.1128/mBio.00915-18
mBio
Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3f24de6873e0d5b0a710b9376bcf4b
https://doaj.org/article/490e351d920d4f639c5a38f24d755ca4
https://doaj.org/article/490e351d920d4f639c5a38f24d755ca4
Autor:
Mark H. T. Stappers, Matteo Zanda, Axel A. Brakhage, Mihai G. Netea, Ivy M. Dambuza, António Campos, Delyth M. Reid, Ten Feizi, Carol Wallace, Betty Hebecker, Jean-Paul Latgé, João F. Lacerda, Neil A. R. Gow, Frank L. van de Veerdonk, Maria da Glória Teixeira de Sousa, Patawee Asamaphan, Kyung J. Kwon-Chung, Monica Piras, Martin Jaeger, Cristina Cunha, Vishukumar Aimanianda, Janet A. Willment, Alexandra E. Clark, Raif Yuecel, Chiara Zanato, Isabel Valsecchi, Yan Liu, Agostinho Carvalho, Bernhard Kerscher, Sarah E. Hardison, Anthony Plato, Stefan Bidula, Gordon D. Brown
Publikováno v:
Nature, 555, 7696, pp. 382-386
Nature
Nature, Nature Publishing Group, 2018, 555 (7696), pp.382-386. ⟨10.1038/nature25974⟩
Nature, 555, 382-386
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature, 2018, 555 (7696), pp.382-386. ⟨10.1038/nature25974⟩
Nature
Nature, Nature Publishing Group, 2018, 555 (7696), pp.382-386. ⟨10.1038/nature25974⟩
Nature, 555, 382-386
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature, 2018, 555 (7696), pp.382-386. ⟨10.1038/nature25974⟩
© 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
Resistance to infection is critically dependent on the ability of pattern recognition receptors to recognize microbial invasion and induce protective immune resp
Resistance to infection is critically dependent on the ability of pattern recognition receptors to recognize microbial invasion and induce protective immune resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff61ca704d5de2aa7a584d3e436cd0b3
https://hdl.handle.net/2066/190136
https://hdl.handle.net/2066/190136
Autor:
Bernhard Hube, Franz Bracher, Philip Stevens, Martin Schaller, Christoph Müller, Daniela Mailänder-Sánchez, Kai Sohn, Stefan Lorenz, Christina Braunsdorf, Betty Hebecker, Christian Grumaz, Jeanette Wagener
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0184438 (2017)
PLoS ONE, Vol 12, Iss 10, p e0184438 (2017)
Candida albicans is an inhabitant of mucosal surfaces in healthy individuals but also the most common cause of fungal nosocomial blood stream infections, associated with high morbidity and mortality. As such life-threatening infections often dissemin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e64c94dec366a19a58e20f54b2f67b
https://pubmed.ncbi.nlm.nih.gov/29023454
https://pubmed.ncbi.nlm.nih.gov/29023454
Publikováno v:
Expert Review of Anti-infective Therapy. 12:867-879
Oral candidiasis remains one of the most common forms of Candida infections and occurs if the balance between host, Candida and microbiota is disturbed, e.g., by broad spectrum antibiotics or immunosuppression. In recent years, identification of fung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d055a98e4e89964e4b28a57cb06830d
https://doi.org/10.1586/14787210.2014.916210
https://doi.org/10.1586/14787210.2014.916210
Autor:
Jörg Linde, Sascha Brunke, Mario Kapitan, Bernhard Hube, Michael Bauer, Betty Hebecker, Ilse D. Jacobsen, Sebastian Vlaic, Theresia Conrad
Publikováno v:
Scientific Reports
Candida albicans is a common cause of life-threatening fungal bloodstream infections. In the murine model of systemic candidiasis, the kidney is the primary target organ while the fungal load declines over time in liver and spleen. To better understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91037a69b3335f687134ff9edddfa375
http://europepmc.org/articles/PMC5172156
http://europepmc.org/articles/PMC5172156
Autor:
Jörg Linde, Michael Bauer, Sebastian Vlaic, Betty Hebecker, Sascha Brunke, Bernhard Hube, Theresia Conrad, Ilse D. Jacobsen, Mario Kapitan
Publikováno v:
Scientific Reports.
Candida albicans is a common cause of life-threatening fungal bloodstream infections. In the murine model of systemic candidiasis, the kidney is the primary target organ while the fungal load declines over time in liver and spleen. To better understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cf2165cdcdec9f4ad6d34df33987da