Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Betty E. Luy"'
Autor:
Claire Y-H Huang, Richard M Kinney, Jill A Livengood, Bethany Bolling, John J Arguello, Betty E Luy, Shawn J Silengo, Karen L Boroughs, Janae L Stovall, Akundi P Kalanidhi, Aaron C Brault, Jorge E Osorio, Dan T Stinchcomb
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2243 (2013)
We have developed a manufacturing strategy that can improve the safety and genetic stability of recombinant live-attenuated chimeric dengue vaccine (DENVax) viruses. These viruses, containing the pre-membrane (prM) and envelope (E) genes of dengue se
Externí odkaz:
https://doaj.org/article/f4fd186079c94a3b8c24a3a99d2d23a7
Autor:
Janae L. Stovall, Janeen Laven, Olga I. Kosoy, Amanda E. Calvert, Karen L. Boroughs, Betty E. Luy, Claire Y.-H. Huang
Publikováno v:
Journal of Clinical Microbiology. 56
Zika virus (ZIKV) has emerged as a major global public health concern due to its link as a causative agent of human birth defects. Laboratory diagnosis of suspected ZIKV infections by serological testing of specimens collected a week or more after sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7b3e390f47cd0a3647a7e0d6d8c670
https://doi.org/10.1128/jcm.00234-18
https://doi.org/10.1128/jcm.00234-18
Autor:
Tina J. T. Dube, Aurelia A. Haller, Janae L. Stovall, Linda M. Eggemeyer, Karen L. Boroughs, Mimi A. Wong, Sharon Irby-Moore, Betty E. Luy, Claire Y.-H. Huang, Jorge E. Osorio, Dan T. Stinchcomb, Sarah L. George, Sharon E. Frey
Publikováno v:
Journal of Infectious Diseases. 212:1032-1041
Background. Dengue viruses (DENVs) infect >300 million people annually, causing 96 million cases of denguedisease and 22000 deaths [1]. A safe vaccine that protects against DENV disease is a global health priority [2].Methods. We enrolled 72 flavivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09d11c6cb176ebbe231a24f8e2d474d
https://doi.org/10.1093/infdis/jiv179
https://doi.org/10.1093/infdis/jiv179
Autor:
Betty E. Luy, Siritorn Butrapet, Kelley J. Moss, Thomas Childers, Carol D. Blair, John T. Roehrig, Amanda E. Calvert, Steven M. Erb, Claire Y.-H. Huang
Publikováno v:
Virology. 413:118-127
Fifteen mutant dengue viruses were engineered and used to identify AAs in the molecular hinge of the envelope protein that are critical to viral infection. Substitutions at Q52, A54, or E133 reduced infectivity in mammalian cells and altered the pH t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb972d97216b54767dce9f46e0265e45
https://doi.org/10.1016/j.virol.2011.01.030
https://doi.org/10.1016/j.virol.2011.01.030
Autor:
Shawn Silengo, Jaclyn Scott, Karen L. Boroughs, Dan T. Stinchcomb, Iván D. Vélez, Alejandra Jiménez, Jorge E. Osorio, Janae L. Stovall, Betty E. Luy, Mark E. Beatty, Aurelia Haller, Claire Y.-H. Huang, Joseph D. Santangelo, Gilad Gordon, Liliana Lopez, Cynthia A. Thomson, John Arguello
Publikováno v:
The Lancet. Infectious diseases. 14(9)
Summary Background Dengue virus is the most serious mosquito-borne viral threat to public health and no vaccines or antiviral therapies are approved for dengue fever. The tetravalent DENVax vaccine contains a molecularly characterised live attenuated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f678abc7883b225a868a206739c2ed
https://pubmed.ncbi.nlm.nih.gov/25087477
https://pubmed.ncbi.nlm.nih.gov/25087477
Autor:
Janae L. Stovall, Jill A Livengood, Shawn J. Silengo, Dan T. Stinchcomb, Karen L. Boroughs, Akundi P. Kalanidhi, Richard M. Kinney, Betty E. Luy, John J. Arguello, Claire Y.-H. Huang, Jorge E. Osorio, Bethany G. Bolling, Aaron C. Brault
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2243 (2013)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background We have developed a manufacturing strategy that can improve the safety and genetic stability of recombinant live-attenuated chimeric dengue vaccine (DENVax) viruses. These viruses, containing the pre-membrane (prM) and envelope (E) genes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c565f3ec2541321afc8532098f60a20e
http://europepmc.org/articles/PMC3667780?pdf=render
http://europepmc.org/articles/PMC3667780?pdf=render
Autor:
Siritorn Butrapet, Thomas Childers, Nathan M. Liss, Betty E. Luy, Karen L. Boroughs, Carol D. Blair, Janae L. Stovall, Susan L. Bennett, Amanda E. Calvert, John T. Roehrig, Claire Y.-H. Huang
Publikováno v:
Virology. 441(2)
Using an infectious cDNA clone we engineered seven mutations in the putative heparan sulfate- and receptor-binding motifs of the envelope protein of dengue virus serotype 2, strain 16681. Four mutant viruses, KK122/123EE, E202K, G304K, and KKK305/307
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6a90f3c2a7fdba11ba5b257ddd6a55
https://pubmed.ncbi.nlm.nih.gov/23571092
https://pubmed.ncbi.nlm.nih.gov/23571092
Autor:
Thomas Childers, John T. Roehrig, Steven M. Erb, Amanda E. Calvert, Carol D. Blair, Shawn J. Silengo, Siritorn Butrapet, Betty E. Luy, Claire Y.-H. Huang, Kelley J. Moss
Publikováno v:
Virology. (2):328-335
The FG extended loop in domain III of the dengue virus type 2 (DENV2) envelope protein is postulated to be a molecular determinant for host cell infectivity. To determine the contribution of the FG loop to virus infectivity, an infectious cDNA clone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a32bdb7e19221534c0db921e95985de