Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Betty, Tijms"'
Autor:
Vikram Venkatraghavan, Betty Tijms, Hugo Kuijf, Alberto de Luca, Esther Bron, Argonde van Harten, Lieza Exalto, Frederik Barkhof, Rik Ossenkoppele, Geert Jan Biessels, Wiesje van der Flier
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100253- (2024)
Introduction: Vascular cognitive impairment (VCI) is heterogeneous in brain atrophy patterns, clinical symptoms, and possibly in the factors affecting resilience to symptoms. The objective of this study was to investigate the heterogeneity of VCI by
Externí odkaz:
https://doaj.org/article/b3aa89989623414498591f84f45ee56f
Autor:
Beatriz Padrela, Amnah Mahroo, Mervin Tee, Markus Sneve, Paulien Moyaert, Oliver Geier, Joost Kuijer, Soetkin Beun, Wibeke Nordhøy, Yufei David Zhu, Mareike Buck, Daniel Hoinkiss, Simon Konstandin, Jörn Huber, Julia Wiersinga, Roos Rikken, Diederick de Leeuw, Håkon Grydeland, Lynette Tippett, Erin Cawston, Esin Ozturk-Isik, Jennifer Linn, Moritz Brandt, Betty Tijms, Elsmarieke van de Giessen, Majon Muller, Anders Fjell, Kristine Walhovd, Lene Pålhaugen, Per Selnes, Patricia Clement, Eric Achten, Udunna Anazodo, Frederik Barkhof, Saima Hilal, Tormod Fladby, Klaus Eickel, Catherine Morgan, David Thomas, Jan Petr, Matthias Günther, Henk J.M.M. Mutsaerts
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100308- (2024)
Introduction: Arterial spin labeling (ASL) MRI, a non-invasive technique for imaging perfusion, now allows studying BBB permeability. The DEveloping BBB-ASL as a non-Invasive Early biomarker of Alzheimer's Disease (DEBBIE-AD) multi-cohort study integ
Externí odkaz:
https://doaj.org/article/f9e4cf3484fb4567aa9f9f8b10272e40
Autor:
Tong Tong, Christian Ledig, Ricardo Guerrero, Andreas Schuh, Juha Koikkalainen, Antti Tolonen, Hanneke Rhodius, Frederik Barkhof, Betty Tijms, Afina W Lemstra, Hilkka Soininen, Anne M Remes, Gunhild Waldemar, Steen Hasselbalch, Patrizia Mecocci, Marta Baroni, Jyrki Lötjönen, Wiesje van der Flier, Daniel Rueckert
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 613-624 (2017)
Differentiating between different types of neurodegenerative diseases is not only crucial in clinical practice when treatment decisions have to be made, but also has a significant potential for the enrichment of clinical trials. The purpose of this s
Externí odkaz:
https://doaj.org/article/b4f1eb19393d42ecaf67314d22594742
Autor:
Aurore Delvenne, Johan Gobom, Betty Tijms, Isabelle Bos, Lianne M. Reus, Valerija Dobricic, Mara ten Kate, Frans Verhey, Inez Ramakers, Philip Scheltens, Charlotte E. Teunissen, Rik Vandenberghe, Jolien Schaeverbeke, Silvy Gabel, Julius Popp, Gwendoline Peyratout, Pablo Martinez‐Lage, Mikel Tainta, Magda Tsolaki, Yvonne Freund‐Levi, Simon Lovestone, Johannes Streffer, Frederik Barkhof, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Pieter Jelle Visser, Stephanie J. B. Vos
Publikováno v:
Alzheimer's & dementia
Delvenne, A, Gobom, J, Tijms, B, Bos, I, Reus, L M, Dobricic, V, Kate, M T, Verhey, F, Ramakers, I, Scheltens, P, Teunissen, C E, Vandenberghe, R, Schaeverbeke, J, Gabel, S, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Tsolaki, M, Freund-Levi, Y, Lovestone, S, Streffer, J, Barkhof, F, Bertram, L, Blennow, K, Zetterberg, H, Visser, P J & Vos, S J B 2022, ' Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology ', Alzheimer's and Dementia . https://doi.org/10.1002/alz.12713
Alzheimer's and Dementia. Elsevier
Alzheimer's & Dementia, 19(3), 807-820. Elsevier Science
Delvenne, A, Gobom, J, Tijms, B, Bos, I, Reus, L M, Dobricic, V, Kate, M T, Verhey, F, Ramakers, I, Scheltens, P, Teunissen, C E, Vandenberghe, R, Schaeverbeke, J, Gabel, S, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Tsolaki, M, Freund-Levi, Y, Lovestone, S, Streffer, J, Barkhof, F, Bertram, L, Blennow, K, Zetterberg, H, Visser, P J & Vos, S J B 2022, ' Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology ', Alzheimer's and Dementia . https://doi.org/10.1002/alz.12713
Alzheimer's and Dementia. Elsevier
Alzheimer's & Dementia, 19(3), 807-820. Elsevier Science
BACKGROUND: Suspected non-Alzheimer's disease pathophysiology (SNAP) is a biomarker concept that encompasses individuals with neuronal injury but without amyloidosis. We aim to investigate the pathophysiology of SNAP, defined as abnormal tau without
Autor:
Luigi Lorenzini, Silvia Ingala, Lyduine E Collij, Viktor Wottschel, Sven Haller, Kaj Blennow, Giovanni Frisoni, Gaël Chételat, Pierre Payoux, Pablo Lage-Martinez, Michael Ewers, Adam Waldman, Joanna Wardlaw, Craig Ritchie, Juan Domingo Gispert, Henk J M M Mutsaerts, Pieter Jelle Visser, Philip Scheltens, Betty Tijms, Frederik Barkhof, Alle Meije Wink
Publikováno v:
Lorenzini, L, Ingala, S, Collij, L E, Wottschel, V, Haller, S, Blennow, K, Frisoni, G, Chételat, G, Payoux, P, Lage-Martinez, P, Ewers, M, Waldman, A, Wardlaw, J, Ritchie, C, Gispert, J D, Mutsaerts, H J M M, Visser, P J, Scheltens, P, Tijms, B, Barkhof, F & Wink, A M 2023, ' Eigenvector centrality dynamics are related to Alzheimer's disease pathological changes in non-demented individuals ', Brain Communications, vol. 5, no. 3, pp. fcad088 . https://doi.org/10.1093/braincomms/fcad088
Brain communications 5(3), fcad088 (2023). doi:10.1093/braincomms/fcad088
Brain Communications, 5(3):fcad088. Oxford University Press
Lorenzini, L, Ingala, S, Collij, L E, Wottschel, V, Haller, S, Blennow, K, Frisoni, G, Chételat, G, Payoux, P, Lage-Martinez, P, Ewers, M, Waldman, A, Wardlaw, J, Ritchie, C, Gispert, J D, Mutsaerts, H J M M, Visser, P J, Scheltens, P, Tijms, B, Barkhof, F & Wink, A M 2023, ' Eigenvector centrality dynamics are related to Alzheimer’s disease pathological changes in non-demented individuals ', Brain Communications, vol. 5, no. 3, fcad088 . https://doi.org/10.1093/braincomms/fcad088
Brain communications 5(3), fcad088 (2023). doi:10.1093/braincomms/fcad088
Brain Communications, 5(3):fcad088. Oxford University Press
Lorenzini, L, Ingala, S, Collij, L E, Wottschel, V, Haller, S, Blennow, K, Frisoni, G, Chételat, G, Payoux, P, Lage-Martinez, P, Ewers, M, Waldman, A, Wardlaw, J, Ritchie, C, Gispert, J D, Mutsaerts, H J M M, Visser, P J, Scheltens, P, Tijms, B, Barkhof, F & Wink, A M 2023, ' Eigenvector centrality dynamics are related to Alzheimer’s disease pathological changes in non-demented individuals ', Brain Communications, vol. 5, no. 3, fcad088 . https://doi.org/10.1093/braincomms/fcad088
Amyloid-beta accumulation starts in highly connected brain regions and is associated with functional connectivity alterations in the early stages of Alzheimer's disease. This regional vulnerability is related to the high neuronal activity and strong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9657eb4ef895dc149f424bb440509025
https://www.pure.ed.ac.uk/ws/files/346906622/fcad088.pdf
https://www.pure.ed.ac.uk/ws/files/346906622/fcad088.pdf
Autor:
Juha Koikkalainen, Hanneke Rhodius-Meester, Antti Tolonen, Frederik Barkhof, Betty Tijms, Afina W. Lemstra, Tong Tong, Ricardo Guerrero, Andreas Schuh, Christian Ledig, Daniel Rueckert, Hilkka Soininen, Anne M. Remes, Gunhild Waldemar, Steen Hasselbalch, Patrizia Mecocci, Wiesje van der Flier, Jyrki Lötjönen
Publikováno v:
NeuroImage: Clinical, Vol 11, Iss C, Pp 435-449 (2016)
Different neurodegenerative diseases can cause memory disorders and other cognitive impairments. The early detection and the stratification of patients according to the underlying disease are essential for an efficient approach to this healthcare cha
Externí odkaz:
https://doaj.org/article/39a7649a6e6f44fa928c088847b12666
Autor:
Ron Handels, Kirsten Wesenhagen, Betty Tijms, Charlotte Teunissen, Pieter Jelle Visser, Linus Jönsson
INTRODUCTIONThree distinct pathophysiological subtypes of Alzheimer’s disease (AD) have been identified based on CSF proteomics. We aim to estimate the potential incremental cost-effectiveness ratio of individualized hypothetical AD pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c523540377d4d48574fe77d34f8d1d1e
https://doi.org/10.1101/2023.01.24.23284478
https://doi.org/10.1101/2023.01.24.23284478
Autor:
Alexander Neumann, Fahri Küçükali, Stephanie Vos, Dmitry Prokopenko, Betty Tijms, Rik Vandenberghe, Cristina Legido-Quigley
Genome-wide association studies (GWAS) of Alzheimer’s disease (AD) have identified several risk loci, but many remain unknown. Cerebrospinal fluid (CSF) biomarkers may aid in gene discovery and we previously demonstrated that six CSF biomarkers (β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::429646ec7c7e3f5df88968168a708b28
https://doi.org/10.1101/2022.08.02.22278185
https://doi.org/10.1101/2022.08.02.22278185
Autor:
Schramm, Catherine, Charbonnier, Camille, Zaréa, Aline, Lacour, Morgane, Wallon, David, Boland, Anne, Deleuze, Jean-François, Olaso, Robert, Alarcon, Flora, Campion, Dominique, Nuel, Grégory, Nicolas, Gaël, Collaborators Daniela Andriuta, Pierre, Anthony, Sophie, Auriacombe, Anna-Chloé, Balageas, Guillaume, Ballan, Mélanie, Barbay, Emilie, Beaufils, Yannick, Béjot, Serge, Belliard, Marie, Benaiteau, Karim, Bennys, Frédéric, Blanc, Stéphanie, Bombois, Claire Boutoleau Bretonnière, Pierre, Branger, Jasmine, Carlier, Leslie, Cartz-Piver, Pascaline, Cassagnaud, Giovanni, Castelnovo, Christine, Champion, Annabelle, Chaussenot, Mathieu, Ceccaldi, Valérie, Chauviré, Yaohua, Chen, Julien, Cogez, Emmanuel, Cognat, Fabienne, Contegal-Callier, Lea, Corneille, Philippe, Couratier, Hélène, Courtemanche, Benjamin, Cretin, Charlotte, Crinquette, Bernard, Croisille, Benjamin, Dauriat, Sophie, Dautricourt, Vincent de la Sayette, Astrid De Liège, Marie De Verdal, Didier, Deffond, Benoit, Delpont, Florence, Demurger, Vincent, Deramecourt, Céline, Derollez, Mira, Didic, Giulia, Diemert, Elsa, Dionet, Philippe, Diraison, Aude, Doan, Martine Doco Fenzy, Boris, Dufournet, Julien, Dumurgier, Hélène, Durand, Anas, Dutray, Frédérique, Etcharry-Bouyx, Maté, Formaglio, Audrey, Gabelle, Anne, Gainche-Salmon, Jean-Claude, Getenet, Emmanuelle, Ginglinger, Olivier, Godefroy, Mathilde, Graber, Chloé, Gregoire, Stephan, Grimaldi, Julien, Gueniat, Claude, Gueriot, Sophie, Haffen, Lorraine, Hamelin, Didier, Hannequin, Cezara, Hanta, Clémence, Hardy, Geoffroy, Hautecloque, Camille, Heitz, Claire, Hourregue, Thérèse, Jonveaux, Snejana, Jurici, Catia, Khoumri, Lejla, Koric, Pierre, Krolak-Salmon, Pierre, Labauge, Morgane, Lacour, Julien, Lagarde, Hélène-Marie, Lanoiselée, Brice, Laurens, Isabelle Le Ber, Gwenaël Le Guyader, Amélie, Leblanc, Thibaud, Lebouvier, Anas, Lippi, Marie-Anne, Mackowiak, Eloi, Magnin, Cecilia, Marelli, Olivier, Martinaud, Aurélien, Maureille, Emilie, Milongo-Rigal, Sophie, Mohr, Hélène, Mollion, Olivier, Moreaud, Alexandre, Morin, Gaël, Nicolas, Julia, Nivelle, Camille, Noiray, Elisabeth, Ollagnon-Roman, Claire, Paquet, Jérémie, Pariente, Florence, Pasquier, Alexandre, Perron, Nathalie, Philippi, Virginie, Pichon, Vincent, Planche, Céline, Poirsier, Marie, Rafiq, Pauline, Rod-Olivieri, Adeline, Rollin-Sillaire, Carole, Roué-Jagot, Dario, Saracino, Marie, Sarazin, Mathilde, Sauvée, François, Sellal, Lila Sirven Villaros, Christel, Thauvin, Camille, Tisserand, Christophe, Tomasino, Cédric, Turpinat, Laurène Van Damme, Olivier, Vercruysse, Alice, Voilly, Nathalie, Wagemann, David, Wallon, Aline, Zarea, Shahzad, Ahmad, Philippe, Amouyel, Claudine, Berr, Anne, Boland, Paola, Bossu, Femke, Bouwman, Jose, Bras, Dominique, Campion, Camille, Charbonnier, Jordi, Clarimon, Antonio, Daniele, Jean-François, Dartigues, Stéphanie, Debette, Jean-François, Deleuze, Nicola, Denning, Oriol, Dols-Icardo, Nick, C Fox, Daniela, Galimberti, Emmanuelle, Génin, Hans, Gille, Benjamin, Grenier-Boley, Detelina, Grozeva, Rita, Guerreiro, John, J Hardy, Clive, Holmes, Henne, Holstege, Marc, Hulsman, Holger, Hummerich, M Arfan Ikram, M Kamran Ikram, Iris, Jansen, Amit, Kawalia, Robert, Kraaij, Jean-Charles, Lambert, Marc, Lathrop, Afina, W Lemstra, Alberto, Lleo, Lauren, Luckcuck, Marcel M A, M Mannens, Rachel, Marshall, Carlo, Masullo, Simon, Mead, Mecocci, Patrizia, Alun, Meggy, Merel, O Mol, Kevin, Morgan, Benedetta, Nacmias, Penny, J Norsworthy, Pau, Pastor, Olivier, Quenez, Alfredo, Ramirez, Rachel, Raybould, Richard, Redon, Marcel J, T Reinders, Anne-Claire, Richard, Steffi, G Riedel-Heller, Fernando, Rivadeneira, Stéphane, Rousseau, Natalie, S Ryan, Salha, Saad, Pascual, Sanchez-Juan, Philip, Scheltens, Jonathan, M Schott, Davide, Seripa, Daoud, Sie, Rebecca, Sims, Erik, Sistermans, Sandro, Sorbi, Resie van Spaendonk, Gianfranco, Spalleta, Nicćolo, Tesi, Betty, Tijms, André, G Uitterlinden, Wiesje, M van der Flier, Sven, J van der Lee, Cornelia, M van Duijn, Jeroen G, J van Rooij, John, C van Swieten, Pieter, J de Visser, Michael, Wagner, Julie, Williams
Publikováno v:
Genome Medicine. 14
Background Alzheimer disease (AD) is a common complex disorder with a high genetic component. Loss-of-function (LoF) SORL1 variants are one of the strongest AD genetic risk factors. Estimating their age-related penetrance is essential before putative
Autor:
Luigi Lorenzini, Loes T Ansems, Isadora Lopes Alves, Silvia Ingala, David Vállez García, Jori Tomassen, Carole Sudre, Gemma Salvadó, Mahnaz Shekari, Gregory Operto, Anna Brugulat-Serrat, Gonzalo Sánchez-Benavides, Mara ten Kate, Betty Tijms, Alle Meije Wink, Henk J M M Mutsaerts, Anouk den Braber, Pieter Jelle Visser, Bart N M van Berckel, Juan Domingo Gispert, Frederik Barkhof, Lyduine E Collij, the AMYPAD consortium, the EPAD consortium, ALFA cohort
White matter hyperintensities (WMH) have a heterogeneous etiology, associated with both vascular risk factors and amyloidosis due to Alzheimer’s disease (AD). While spatial distribution of both amyloid and WM lesions carry important information for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::a03a4d980095449f24315b7d1f66ead1
https://zenodo.org/record/6794199
https://zenodo.org/record/6794199