Autoimmune CD4 ⁺ T cells fine-tune TCF1 expression to maintain function and survive persistent antigen exposure during diabetes.

Autor: Aljobaily N; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Allard D; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Perkins B; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Raugh A; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Galland T; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Jing Y; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Stephens WZ; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Bettini ML; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Hale JS; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA., Bettini M; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA. Electronic address: maria.bettini@path.utah.edu.

Publikováno v: Immunity [Immunity] 2024 Nov 12; Vol. 57 (11), pp. 2583-2596.e6. Date of Electronic Publication: 2024 Oct 12.

Early-life microbiota-immune homeostasis.

Autor: Reynolds HM; Department of Microbiology and Immunology, University of Utah, Salt Lake, UT, United States., Bettini ML; Department of Microbiology and Immunology, University of Utah, Salt Lake, UT, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Oct 23; Vol. 14, pp. 1266876. Date of Electronic Publication: 2023 Oct 23 (Print Publication: 2023).

Host-microbiota interactions shaping T-cell response and tolerance in type 1 diabetes.

Autor: Majumdar S; Immunology Graduate Program, Baylor College of Medicine, Houston, TX, United States.; Department of Pathology, University of Utah, Salt Lake City, UT, United States., Lin Y; Immunology Graduate Program, Baylor College of Medicine, Houston, TX, United States.; Department of Pathology, University of Utah, Salt Lake City, UT, United States., Bettini ML; Department of Pathology, University of Utah, Salt Lake City, UT, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Aug 18; Vol. 13, pp. 974178. Date of Electronic Publication: 2022 Aug 18 (Print Publication: 2022).

A dormant T-cell population with autoimmune potential exhibits low self-reactivity and infiltrates islets in type 1 diabetes.

Autor: Kong Y; Section of Diabetes and Endocrinology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA., Jing Y; Section of Diabetes and Endocrinology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.; Department of Pathology, Microbiology and Immunology, University of Utah, Salt Lake City, UT, USA., Allard D; Department of Pathology, Microbiology and Immunology, University of Utah, Salt Lake City, UT, USA., Scavuzzo MA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA., Sprouse ML; Section of Diabetes and Endocrinology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA., Borowiak M; Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.; Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.; McNair Medical Institute, Houston, TX, USA., Bettini ML; Section of Diabetes and Endocrinology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.; Department of Pathology, Microbiology and Immunology, University of Utah, Salt Lake City, UT, USA.; McNair Medical Institute, Houston, TX, USA., Bettini M; Section of Diabetes and Endocrinology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.; Department of Pathology, Microbiology and Immunology, University of Utah, Salt Lake City, UT, USA.; McNair Medical Institute, Houston, TX, USA.

Publikováno v: European journal of immunology [Eur J Immunol] 2022 Jul; Vol. 52 (7), pp. 1158-1170. Date of Electronic Publication: 2022 Apr 22.

Function, Failure, and the Future Potential of Tregs in Type 1 Diabetes.

Autor: Bettini M; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT matt.bettini@path.utah.edu maria.bettini@path.utah.edu., Bettini ML; Division of Microbiology and Immunology, Department of Pathology, University of Utah, Salt Lake City, UT matt.bettini@path.utah.edu maria.bettini@path.utah.edu.

Publikováno v: Diabetes [Diabetes] 2021 Jun; Vol. 70 (6), pp. 1211-1219. Date of Electronic Publication: 2021 May 20.