Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bettina Tomaselli"'
Publikováno v:
Molecular and Cellular Neuroscience. 38:559-568
Purine nucleosides protect neurons against hypoxic insult, but the signaling mechanisms have not yet been fully elucidated. We studied the role of the p42/44 MAPK pathway in purine nucleoside-mediated protection of cultured PC12 cells and primary cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3a8bfd835e92ed2692bfe7a70c71cc
https://doi.org/10.1016/j.mcn.2008.05.004
https://doi.org/10.1016/j.mcn.2008.05.004
Autor:
Leopold Lang, I. Haller, Lars Klimaschewski, Peter Gerner, Hans Peter Colvin, Philipp Lirk, Bettina Tomaselli
Publikováno v:
Anesthesia and analgesia, 106(5), 1456-64, table of contents. Lippincott Williams and Wilkins
Animal models show us that specific activation of the p38 mitogen-activated protein kinase (MAPK) may be a pivotal step in lidocaine neurotoxicity, but this has not been investigated in the case of two very widely used local anesthetics, bupivacaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376abd7acaa4d9bc84ea517a85964db4
https://doi.org/10.1213/ane.0b013e318168514b
https://doi.org/10.1213/ane.0b013e318168514b
Autor:
Günther Böck, Gabriele Baier-Bitterlich, Bettina Tomaselli, Valerie Podhraski, Veronika Heftberger
Publikováno v:
Neurochemistry International. 46:513-521
Hypoxia in brain may lead to cell death by apoptosis and necrosis. Concomitant is the formation of purine nucleosides, e.g. adenosine, a powerful endogenous neuroprotectant. Despite vigorous studies, many aspects of the mechanisms involved in purine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7404b4dc2e83f2dcb19d3f0db5dee2
https://doi.org/10.1016/j.neuint.2005.02.003
https://doi.org/10.1016/j.neuint.2005.02.003
Publikováno v:
American Journal of Biochemistry and Biotechnology. 1:160-166
Hypoxia in brain may lead to cell death by apoptosis and necrosis. In parallel adenosine, a powerful endogenous neuroprotectant is formed. We wanted to investigate the effect of adenosine and its purine nucleoside relatives, inosine and guanosine on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be7eb102edc475ca528ddf8c787790b4
https://doi.org/10.3844/ajbbsp.2005.160.166
https://doi.org/10.3844/ajbbsp.2005.160.166
Autor:
Bettina Tomaselli, Günther Böck, Gabriele Baier-Bitterlich, Dietmar Fuchs, Christiane Enzinger, Gottfried Baier, Christina Lutz, Barbara Wirleitner
Publikováno v:
European Journal of Cell Biology. 81:197-202
Activated cell-mediated immunity is known to be accompanied by elevated concentrations of 7,8-dihydroneopterin which in high concentrations was found to interfere with the oxidant-antioxidant balance. In this study we investigated whether 7,8-dihydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f105f9ddad539aa0b9c2e93fb80eda6
https://doi.org/10.1078/0171-9335-00236
https://doi.org/10.1078/0171-9335-00236
Hypoxia-inducible factor-1 alpha (HIF-1alpha) and purine nucleosides adenosine and inosine are critical mediators of physiological responses to acute and chronic hypoxia. The specific aim of this paper was to evaluate the potential role of HIF-1alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f5c3ac690053899823e16b4753b5e8
https://europepmc.org/articles/PMC2992945/
https://europepmc.org/articles/PMC2992945/
Autor:
Philipp Lirk, Lars Klimaschewski, Barbara Hausott, I. Haller, Peter Gerner, Christian Keller, Bettina Tomaselli
Publikováno v:
Anesthesiology, 105(5), 1024-1033. Lippincott Williams and Wilkins
Background Pharmacologic inhibition of the p38 mitogen-activated protein kinase (MAPK) leads to a reduction in lidocaine neurotoxicity in vitro and in vivo. The current study investigated in vitro the hypotheses that lidocaine neurotoxicity is specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee58fd0fa56a726a8ef5ce1f4ce3ab82
https://pure.amc.nl/en/publications/neurotoxicity-of-lidocaine-involves-specific-activation-of-the-p38-mitogenactivated-protein-kinase-but-not-extracellular-signalregulated-or-cjun-nterminal-kinases-and-is-mediated-by-arachidonic-acid-metabolites(ae0dfbf3-d445-43ab-a7df-d3fca68a2fea).html
https://pure.amc.nl/en/publications/neurotoxicity-of-lidocaine-involves-specific-activation-of-the-p38-mitogenactivated-protein-kinase-but-not-extracellular-signalregulated-or-cjun-nterminal-kinases-and-is-mediated-by-arachidonic-acid-metabolites(ae0dfbf3-d445-43ab-a7df-d3fca68a2fea).html
Autor:
Christine E. Bandtlow, Bettina Tomaselli, Veronika Heftberger, Karl Böcklinger, Valerie Podhraski, Gabriele Baier-Bitterlich
Publikováno v:
European journal of cell biology. 83(2)
Mammalian neurons require a constant supply of oxygen to maintain adequate cellular functions and survival. Following sustained hypoxia during ischemic events in brain, the energy status of neurons and glia is compromised, which may subsequently lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571e5ba7a252fe6073439d567adbffe2
https://pubmed.ncbi.nlm.nih.gov/15146976
https://pubmed.ncbi.nlm.nih.gov/15146976
Autor:
Karl Böcklinger1, Bettina Tomaselli1, Veronika Heftberger1, Valerie Podhraski1, Christine Bandtlow1, Gabriele Baier-Bitterlich1
Publikováno v:
European Journal of Cell Biology. Mar2004, Vol. 83 Issue 2, p51-54. 4p.