Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bettina Noll"'
Autor:
Alexander Rau, Katharina Kocher, Mirjam Rommel, Lennart Kühl, Maximilian Albrecht, Hannes Gotthard, Nadine Aschmoneit, Bettina Noll, Monilola A. Olayioye, Roland E. Kontermann, Oliver Seifert
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Dual targeting of surface receptors with bispecific antibodies is attracting increasing interest in cancer therapy. Here, we present a novel bivalent and bispecific antagonistic molecule (Dab-Fc) targeting human epidermal growth factors 2 and 3 (HER2
Externí odkaz:
https://doaj.org/article/8f87b491057b4795a191a891a563a0e7
Publikováno v:
Cells, Vol 8, Iss 12, p 1478 (2019)
As membrane-associated master regulators of cytoskeletal remodeling, Rho GTPases coordinate a wide range of biological processes such as cell adhesion, motility, and polarity. In the last years, Rho GTPases have also been recognized to control intrac
Externí odkaz:
https://doaj.org/article/4f895062395c444ba057a2d9d1751087
Autor:
Cristiana Lungu, Florian Meyer, Marcel Hörning, Jasmin Steudle, Anja Braun, Bettina Noll, David Benz, Felix Fränkle, Simone Schmid, Stephan A. Eisler, Monilola A. Olayioye
The control of intracellular membrane trafficking by Rho GTPases is central to cellular homeostasis. How defined pairs of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs) come together to locally balance GTPase activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::036c38c0b02aa1db19aa6d8f18b03aef
https://doi.org/10.1101/2022.03.01.482527
https://doi.org/10.1101/2022.03.01.482527
Autor:
Oliver Seifert, Monilola A. Olayioye, Alexander Rau, Lennart Kühl, Maximilian Albrecht, Mirjam Rommel, Katharina Kocher, Nadine Aschmoneit, Bettina Noll, Roland E. Kontermann, Hannes Gotthard
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Dual targeting of surface receptors with bispecific antibodies is attracting increasing interest in cancer therapy. Here, we present a novel bivalent and bispecific antagonistic molecule (Dab-Fc) targeting human epidermal growth factors 2 and 3 (HER2
Autor:
Bettina Noll, David Benz, Peter L. Hordijk, Monilola A. Olayioye, Stephan A. Eisler, Yannick Frey, Simone Schmid, Manuel Lauinger, Florian Meyer
Publikováno v:
Journal of Cell Science, 132(11):jcs223172. Company of Biologists Ltd
Journal of cell science, 132(11). Company of Biologists Ltd
Noll, B, Benz, D, Frey, Y, Meyer, F, Lauinger, M, Eisler, S A, Schmid, S, Hordijk, P L & Olayioye, M A 2019, ' DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes ', Journal of Cell Science, vol. 132, no. 11, jcs223172 . https://doi.org/10.1242/jcs.223172
Journal of cell science, 132(11). Company of Biologists Ltd
Noll, B, Benz, D, Frey, Y, Meyer, F, Lauinger, M, Eisler, S A, Schmid, S, Hordijk, P L & Olayioye, M A 2019, ' DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes ', Journal of Cell Science, vol. 132, no. 11, jcs223172 . https://doi.org/10.1242/jcs.223172
Cancer cells degrade the extracellular matrix through actin-rich protrusions termed invadopodia. The formation of functional invadopodia requires polarized membrane trafficking driven by Rho GTPase-mediated cytoskeletal remodeling. We identify the Rh
Publikováno v:
BIOspektrum. 22:369-372
Metastatic cancers are characterized by uncontrolled cell proliferation and tissue invasion, processes controlled by small Rho GTPases, the activation of which is regulated by GEF and GAP proteins. Deleted in liver cancer (DLC) proteins are such Rho