Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Bettina M. Nestl"'
Publikováno v:
Catalysts, Vol 9, Iss 3, p 252 (2019)
A novel approach for the synthesis of vanillin employing a three-step two-enzymatic cascade sequence is reported. Cytochrome P450 monooxygenases are known to catalyse the selective hydroxylation of aromatic compounds, which is one of the most challen
Externí odkaz:
https://doaj.org/article/11a0baa8a0bd4269aa0551f05077cc84
Autor:
Ana C. Fernandes, Julia M. Halder, Bettina M. Nestl, Bernhard Hauer, Krist V. Gernaey, Ulrich Krühne
Publikováno v:
Bioengineering, Vol 5, Iss 2, p 30 (2018)
Selective oxidative functionalization of molecules is a highly relevant and often demanding reaction in organic chemistry. The use of biocatalysts allows the stereo- and regioselective introduction of oxygen molecules in organic compounds at milder c
Externí odkaz:
https://doaj.org/article/6e72a2f956094a558dfdde26cb3796ec
Autor:
Jürgen Pleiss, Bettina M. Nestl, Mahima Sharma, Benjamin Aberle, Gideon Grogan, Niels Borlinghaus, Peter Stockinger
Publikováno v:
ChemCatChem. 13:5210-5215
Imine reductases (IREDs) offer biocatalytic routes to chiral amines and have a natural preference for the NADPH cofactor. In previous work, we reported enzyme engineering of the (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3719ab91c4b5a367a1360fa73a00eda7
https://doi.org/10.1002/cctc.202101057
https://doi.org/10.1002/cctc.202101057
Publikováno v:
ChemCatChem. 13:3405-3409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9a00bed7cc81288c6d2d8a6eba46a09
https://doi.org/10.1002/cctc.202100452
https://doi.org/10.1002/cctc.202100452
Autor:
Patrick C. F. Buchholz, Bettina M. Nestl, Benedikt Schober, Jürgen Pleiss, Luca Schelle, Peter Stockinger
Publikováno v:
Chembiochem
The β‐hydroxyacid dehydrogenase from Thermocrinus albus (Ta‐βHAD), which catalyzes the NADP+‐dependent oxidation of β‐hydroxyacids, was engineered to accept imines as substrates. The catalytic activity of the proton‐donor variant K189D w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730303aae6b7cde6756eb80890ee7b60
https://doi.org/10.1002/cbic.202000526
https://doi.org/10.1002/cbic.202000526
Autor:
Lars Lauterbach, Ulf-Peter Apfel, Ammar Al-Shameri, Bettina M. Nestl, Kai junge Puring, Marie‐Christine Petrich
Publikováno v:
Angewandte Chemie. 132:11021-11025
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1834d581c2bb9330b9ef9a636cab4538
https://doi.org/10.1002/ange.202001302
https://doi.org/10.1002/ange.202001302
Autor:
Lars Lauterbach, Niels Borlinghaus, Bettina M. Nestl, Bernhard Hauer, Anne-Sophie Coquel, Claus Lattemann, Leonie Weinmann, Philipp N. Scheller, Florian Krimpzer, Ammar Al-Shameri
Publikováno v:
ChemCatChem. 11:5738-5742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ee1640bde853897893fe3a2b69392a
https://doi.org/10.1002/cctc.201900702
https://doi.org/10.1002/cctc.201900702
Autor:
Ammar Al-Shameri, Niels Borlinghaus, Leonie Weinmann, Philipp N. Scheller, Bettina M. Nestl, Lars Lauterbach
Publikováno v:
Green Chemistry. 21:1396-1400
We designed a novel H2-driven cascade for the biosynthesis ofN-heterocycles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ed14b0929cdd1ef68c8f0690f90facf
https://doi.org/10.1039/c8gc03798a
https://doi.org/10.1039/c8gc03798a
Autor:
Kai junge Puring, Bettina M. Nestl, Ulf-Peter Apfel, Lars Lauterbach, Marie‐Christine Petrich, Ammar Al-Shameri
Publikováno v:
Angewandte Chemie (International Ed. in English)
We have developed a scalable platform that employs electrolysis for an in vitro synthetic enzymatic cascade in a continuous flow reactor. Both H2 and O2 were produced by electrolysis and transferred through a gas‐permeable membrane into the flow sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764b7da9451640c4eba4120c92a70b75
https://publica.fraunhofer.de/handle/publica/263719
https://publica.fraunhofer.de/handle/publica/263719
Autor:
Bettina M. Nestl, Silvia Fademrecht, Maike Lenz, Juergen Pleiss, Mahima Sharma, Gideon Grogan
Publikováno v:
Protein Engineering, Design and Selection. 31:109-120
We report the exploration of the evolutionary relationship between imine reductases (IREDs) and other dehydrogenases. This approach is informed by the sequence similarity between these enzyme families and the recently described promiscuous activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51d2a8f4fb275ed7a89a44e79e117c7
https://doi.org/10.1093/protein/gzy006
https://doi.org/10.1093/protein/gzy006