Výsledky vyhledávání - "Bettina M. Kaminski"

Selective Glucocorticoid Receptor Agonists for the Treatment of Inflammatory Bowel Disease: Studies in Mice with Acute Trinitrobenzene Sulfonic Acid Colitis

Autor: Christian Grunwitz, Bettina M. Kaminski, Jürgen Stein, Dieter Steinhilber, Heinfried H. Radeke, Kerstin C. Reuter

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 341:68-80

Despite being a mainstay of inflammatory bowel disease (IBD) therapy, glucocorticoids (GCs) still carry significant risks with respect to unwanted side effects. Alternative drugs with a more favorable risk/benefit ratio than common GCs are thus highl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acb554f6a1fe6f1acbbde82de7cb115
https://doi.org/10.1124/jpet.111.183947

Zobrazit plný text záznamu

Sulforaphane potentiates oxaliplatin-induced cell growth inhibition in colorectal cancer cells via induction of different modes of cell death

Autor: Bernhard Brüne, Jürgen Stein, Marco Schumacher, Sandra Ulrich, Uwe Wenzel, Dieter Steinhilber, Andreas Weigert, Bettina M. Kaminski

Publikováno v: Cancer Chemotherapy and Pharmacology. 67:1167-1178

The objective of this study was to investigate, whether the plant-derived isothiocyanate Sulforaphane (SFN) enhances the antitumor activities of the chemotherapeutic agent oxaliplatin (Ox) in a cell culture model of colorectal cancer. Caco-2 cells we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2540d3cc52d9faf6dc39833011ab8e
https://doi.org/10.1007/s00280-010-1413-y

Zobrazit plný text záznamu

Resveratrol-induced potentiation of the antitumor effects of oxaliplatin is accompanied by an altered cytokine profile of human monocyte-derived macrophages

Autor: Stephanie Ley, Dieter Steinhilber, Bernhard Brüne, Andreas Weigert, Jürgen Stein, Kerstin Brecht, Bianca Gilbert, Sandra Ulrich-Rückert, Bettina M. Kaminski, Maria-Christina Scherzberg

Publikováno v: Apoptosis : an international journal on programmed cell death. 19(7)

The objective of this study was to investigate, whether the naturally occurring polyphenol resveratrol (Res) enhances the anti-tumor activities of the chemotherapeutic agent oxaliplatin (Ox) in a cell culture model of colorectal cancer, also with reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0deb0593cd31d0b67263149ebd7d9fca
https://pubmed.ncbi.nlm.nih.gov/24715262

Zobrazit plný text záznamu

Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-β/Smad signaling pathway

Autor: Jürgen Stein, Sandra Ulrich, Stefan Loitsch, Kerstin C. Reuter, Dieter Steinhilber, Meike J. Ochs, Bettina M. Kaminski

Publikováno v: Molecular nutritionfood research. 54(10)

Scope: The objective of this study was to elucidate molecular mechanisms behind the antitumor activities of the isothiocyanate sulforaphane (SFN) in colorectal cancer cells. Methods and results: Cell growth was determined by BrdU incorporation and cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cb412080ab61553bea683c1e279746
https://pubmed.ncbi.nlm.nih.gov/20603835

Zobrazit plný text záznamu

Phytochemicals resveratrol and sulforaphane as potential agents for enhancing the anti-tumor activities of conventional cancer therapies

Autor: Jürgen Stein, Bettina M. Kaminski, Dieter Steinhilber, Sandra Ulrich

Publikováno v: Current pharmaceutical biotechnology. 13(1)

Even though conventional cancer therapies, comprising surgery and chemo- and radiotherapy, play an important role in the treatment of most solid tumours, successful therapeutic outcome is often limited due to high toxicity and related side-effects, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b793991495156a5e65c2e616e5cd06
https://pubmed.ncbi.nlm.nih.gov/21466425

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání