Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Bettina M Willie"'
Autor:
Junning Chen, Marta Aido, Andreas Roschger, Alexander van Tol, Sara Checa, Bettina M Willie, Richard Weinkamer
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303515 (2024)
Osteocyte lacuno-canalicular network (LCN) is comprised of micrometre-sized pores and submicrometric wide channels in bone. Accumulating evidence suggests multiple functions of this network in material transportation, mechanobiological signalling, mi
Externí odkaz:
https://doaj.org/article/b383193e46aa44f3bf3852fa8688e951
Autor:
Anne-Frédérique Turcotte, Sarah O'Connor, Suzanne N Morin, Jenna C Gibbs, Bettina M Willie, Sonia Jean, Claudia Gagnon
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252487 (2021)
BackgroundThe association between obesity and fracture risk may be skeletal site- and sex-specific but results among studies are inconsistent. Whilst several studies reported higher bone mineral density (BMD) in patients with obesity, altered bone qu
Externí odkaz:
https://doaj.org/article/e8563bb57c5240d38964833c3ed711e6
Publikováno v:
eLife, Vol 7 (2018)
Bone cells sense and actively adapt to physical perturbations to prevent critical damage. ATP release is among the earliest cellular responses to mechanical stimulation. Mechanical stimulation of a single murine osteoblast led to the release of 70 ±
Externí odkaz:
https://doaj.org/article/186c84c71a1246caba150e4e7f6a9646
A FINITE ELEMENT MODEL OF IN VIVO MOUSE TIBIAL COMPRESSION LOADING: INFLUENCE OF BOUNDARY CONDITIONS
Publikováno v:
Facta Universitatis. Series: Mechanical Engineering, Vol 12, Iss 3, Pp 195-207 (2014)
Though bone is known to adapt to its mechanical challenges, the relationship between the local mechanical stimuli and the adaptive tissue response seems so far unclear. A major challenge appears to be a proper characterization of the local mechanical
Externí odkaz:
https://doaj.org/article/a685a1bdc4d44e2fb85f9f99afab00be
Autor:
Ana K. Rentsch, Alexandra Harlander, Janice M. Siegford, Isabela Vitienes, Bettina M. Willie, Tina M. Widowski
Publikováno v:
Frontiers in Animal Science, Vol 4 (2023)
IntroductionTo prepare laying hens for life in cage-free aviaries, they must be reared in aviaries that accustom them to the challenges of navigating a complex three-dimensional structure. Rearing aviaries vary in design and contain a brooding compar
Externí odkaz:
https://doaj.org/article/b3f99cdafc504bcbb81a36dc0efde992
Autor:
Matthew Goldsmith, Sequoia D. Crooks, Sean F. Condon, Bettina M. Willie, Svetlana V. Komarova
Publikováno v:
npj Microgravity, Vol 8, Iss 1, Pp 1-14 (2022)
Abstract Studying the effects of space travel on bone of experimental animals provides unique advantages, including the ability to perform post-mortem analysis and mechanical testing. To synthesize the available data to assess how much and how consis
Externí odkaz:
https://doaj.org/article/50edfda4f82b4249b7dfe002abf8981b
Autor:
Haisheng Yang, Alexander Büttner, Laia Albiol, Catherine Julien, Tobias Thiele, Christine Figge, Ina Kramer, Michaela Kneissel, Georg N. Duda, Sara Checa, Bettina M. Willie
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Loss-of-function mutations in the Sost gene lead to high bone mass phenotypes. Pharmacological inhibition of Sost/sclerostin provides a new drug strategy for treating osteoporosis. Questions remain as to how physical activity may affect bone
Externí odkaz:
https://doaj.org/article/1dceab63af8746c094663a625e692c5c
Autor:
Andreas Roschger, Alexander F. van Tol, Michael Thelen, Anne Seliger, Haisheng Yang, Wing Lee Chan, Tobias Thiele, Paul Roschger, Georg N. Duda, Paul Zaslansky, Uwe Kornak, Bettina M. Willie, Richard Weinkamer
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100396- (2020)
Externí odkaz:
https://doaj.org/article/b31d81d8d4a3431088bbc4c9a7256da1
Autor:
Ruisen Fu, Yili Feng, David Bertrand, Tianming Du, Youjun Liu, Bettina M. Willie, Haisheng Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11734 (2021)
Distraction osteogenesis (DO) is a mechanobiological process of producing new bone and overlying soft tissues through the gradual and controlled distraction of surgically separated bone segments. The process of bone regeneration during DO is largely
Externí odkaz:
https://doaj.org/article/a177532304d448118a3e599a40164c33
Autor:
Ruisen Fu, Yang Liu, Fei Song, Jizhi Fu, Tianming Du, Youjun Liu, Bettina M. Willie, Haisheng Yang
Publikováno v:
Journal of Orthopaedic Research.