Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bettina K. J. Hetfeld"'
Autor:
Heiko Neuss, Santosh Nigam, Xiaohua Huang, Wolfgang Dubiel, Rupal Deva, Wolfgang Schwenk, Julian W. Mall, Bettina K. J. Hetfeld, Petra Henklein
Publikováno v:
Journal of Molecular Medicine. 85:961-970
The cyclooxygenase-2 (COX-2) enzyme is induced upon inflammation and in neoplastic tissues. It produces prostaglandins that stimulate tumor angiogenesis and tumor growth. Therefore, destruction and/or specific inhibition of COX-2 should be an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf4fa4f190478306e4e5d05d9af1078
https://doi.org/10.1007/s00109-007-0197-y
https://doi.org/10.1007/s00109-007-0197-y
Autor:
Wolfgang Dubiel, Bettina K. J. Hetfeld, Michael Naumann, Dawadschargal Bech-Otschir, Xiaohua Huang, Peter-Michael Kloetzel, Thilo Kähne, Ulrike Seifert
Publikováno v:
FEBS Journal. 272:3909-3917
The COP9 signalosome (CSN) occurs in all eukaryotic cells. It is a regulatory particle of the ubiquitin (Ub)/26S proteasome system. The eight subunits of the CSN possess sequence homologies with the polypeptides of the 26S proteasome lid complex and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5affc86a86034268759d57024313515b
https://doi.org/10.1111/j.1742-4658.2005.04807.x
https://doi.org/10.1111/j.1742-4658.2005.04807.x
Autor:
Andreas Peth, Gerald M. Cohen, Bettina K. J. Hetfeld, Peter Henklein, Xiao-Ming Sun, Wolfgang Dubiel
Publikováno v:
Apoptosis : an international journal on programmed cell death. 13(2)
In concert with the ubiquitin (Ub) proteasome system (UPS) the COP9 signalosome (CSN) controls the stability of cellular regulators. The CSN interacts with cullin-RING Ub ligases (CRLs) consisting of a specific cullin, a RING protein as Rbx1 and subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2f5023def9e67400c1fef0b95e8d78
https://pubmed.ncbi.nlm.nih.gov/18060501
https://pubmed.ncbi.nlm.nih.gov/18060501
Publikováno v:
123. Kongress der Deutschen Gesellschaft für Chirurgie; 20060502-20060505; Berlin; DOC06dgch5579 /20060502/
Chirurgisches Forum 2006 ISBN: 9783540324805
Chirurgisches Forum 2006 ISBN: 9783540324805
Wir konnten die Existenz von Superkomplexen bestehend aus beta-Catenin, CSN, CRLs und APC nachweisen. Diese Komplexe sind hochstwahrscheinlich verantwortlich fur einen gerichteten Abbau des beta-Catenins uber das Ubiquitin-Proteasom-System. Weitere E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3f04a991f8b820bd5d4bd21af58234
http://www.egms.de/en/meetings/dgch2006/06dgch518.shtml
http://www.egms.de/en/meetings/dgch2006/06dgch518.shtml
Publikováno v:
Methods in enzymology. 398
The COP9 signalosome (CSN) is a multimeric protein complex that occurs in all eukaryotic cells. Originally described in plants as a regulator of photomorphogenesis, its purification and characterization from mammalian cells revealed significant seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3702c25297d4d93894cdf0edcbd83bf
https://pubmed.ncbi.nlm.nih.gov/16275352
https://pubmed.ncbi.nlm.nih.gov/16275352
Autor:
Xiaohua, Huang, Bettina K J, Hetfeld, Ulrike, Seifert, Thilo, Kähne, Peter-Michael, Kloetzel, Michael, Naumann, Dawadschargal, Bech-Otschir, Wolfgang, Dubiel
Publikováno v:
The FEBS journal. 272(15)
The COP9 signalosome (CSN) occurs in all eukaryotic cells. It is a regulatory particle of the ubiquitin (Ub)/26S proteasome system. The eight subunits of the CSN possess sequence homologies with the polypeptides of the 26S proteasome lid complex and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02636314a52dac515ae4cc27384e4dab
https://pubmed.ncbi.nlm.nih.gov/16045761
https://pubmed.ncbi.nlm.nih.gov/16045761
The COP9 signalosome (CSN) is a multimeric protein complex that occurs in all eukaryotic cells. Originally described in plants as a regulator of photomorphogenesis, its purification and characterization from mammalian cells revealed significant seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d85367d2cd716dd854f56d64a3f8bfe6
https://doi.org/10.1016/s0076-6879(05)98039-7
https://doi.org/10.1016/s0076-6879(05)98039-7
Publikováno v:
BMC Genetics. 3:15
Background The COP9/signalosome (CSN), a multiprotein complex consisting of eight subunits, is implicated in a wide variety of regulatory processes including cell cycle control, signal transduction, transcriptional activation, and plant photomorphoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab4231600c9de449fa3dcb46b37ea333
https://doi.org/10.1186/1471-2156-3-15
https://doi.org/10.1186/1471-2156-3-15