Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Bettina Heid"'
Autor:
Zhuang Wang, Bettina Heid, Ran Lu, Mohit Sachdeva, Michael R. Edwards, JingJing Ren, Thomas E. Cecere, Deena Khan, Taschua Jeboda, David G. Kirsch, Christopher M. Reilly, Rujuan Dai, S. Ansar Ahmed
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Dysregulated miRNAs have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Our previous study reported a substantial increase in three miRNAs located at the miR-183-96-182 cluster (miR-183C) in several autoimmune lupus-prone
Externí odkaz:
https://doaj.org/article/eb151dfa161c4f3db25223486d538a76
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Previous studies have reported that deletion of the transcription factor, early growth response protein 2 (EGR2), in normal C57BL/6 (B6) resulted in the development of lupus-like autoimmune disease. However, increased EGR2 expression has been noted i
Externí odkaz:
https://doaj.org/article/57ed76d973674108bfd16f1963a4c453
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Recent studies have shown that early growth response 2 (EGR2) is highly induced in activated T cells and regulates T cell functions. In normal C57BL/6 (B6) mice, deletion of EGR2 in lymphocytes results in the development of lupus-
Externí odkaz:
https://doaj.org/article/deffe2749cf04e099a1bbe5273540abd
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 12, Pp 1517-1527 (2017)
Eosinophilic esophagitis (EoE) is an allergic disease of the esophagus driven by T cell and eosinophil responses to dietary allergens, resulting in chronic mucosal inflammation. Few spontaneous animal models of esophageal eosinophilia exist, with mos
Externí odkaz:
https://doaj.org/article/464073cd57574979b6283e52ca21b688
Autor:
Rujuan Dai, Catharine Cowan, Bettina Heid, Deena Khan, Zhihong Liang, Christine T N Pham, S Ansar Ahmed
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172105 (2017)
Estrogen, a natural immunomodulator, regulates the development and function of diverse immune cell types. There is now renewed attention on neutrophils and neutrophil serine proteases (NSPs) such as neutrophil elastase (NE), proteinase 3 (PR3), and c
Externí odkaz:
https://doaj.org/article/9fa18e66d7b74f4ebf90d99c466153c8
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14302 (2010)
Recent reports have shown that microRNAs (miRNAs) regulate vital immunological processes and have emerged as key regulators of immune system development and function. Therefore, it is important to determine miRNA dysregulation and its pathogenic cont
Externí odkaz:
https://doaj.org/article/acb7c9a30655470eb4b273064e73c8c6
Autor:
Helena F. Pernice, Adrian L. Knorz, Paul J. Wetzel, Carolin Herrmann, Harisa Muratovic, Finn Rieber, Eleonora Asaad, Gunnar Fiß, Gina Barzen, Elisabeth Blüthner, Fabian Knebel, Sebastian Spethmann, Daniel Messroghli, Bettina Heidecker, Anna Brand, Christoph Wetz, Carsten Tschöpe, Katrin Hahn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In contrast to inherited transthyretin amyloidosis (A-ATTRv), neuropathy is not a classic leading symptom of wild type transthyretin amyloidosis (A-ATTRwt). However, neurological symptoms are increasingly relevant in A-ATTRwt as well. To bet
Externí odkaz:
https://doaj.org/article/7b15ceb0ae92486791a996e76dd4bad1
Autor:
Maximilian Leo Müller, Ekaterina Latinova, Anna Brand, Isabel Mattig, Sebastian Spethmann, Daniel Messroghli, Katrin Hahn, Ulf Landmesser, Bettina Heidecker
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background Results from ATTR‐ACT (Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy) indicate that tafamidis prolongs survival and reduces cardiovascular hospitalizations in cardiac transthyretin amyloidosis (ATTR‐CA)
Externí odkaz:
https://doaj.org/article/d5882afb77134ed4b953157ff190df27
Publikováno v:
American Heart Journal Plus, Vol 43, Iss , Pp 100412- (2024)
Background: The diagnosis of myocarditis remains challenging due to its diverse clinical manifestations. We recently demonstrated the ability of magnetocardiography (MCG) to screen for myocarditis and applied it successfully to detect myocarditis in
Externí odkaz:
https://doaj.org/article/8493ae3b6a444b31a2664a9c30f53177
Autor:
Christopher M. Reilly, S. Ansar Ahmed, Xiguang Xu, Hehuang David Xie, Bettina Heid, Rujuan Dai
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-14 (2020)
BMC Immunology
BMC Immunology
Background Recent studies have shown that early growth response 2 (EGR2) is highly induced in activated T cells and regulates T cell functions. In normal C57BL/6 (B6) mice, deletion of EGR2 in lymphocytes results in the development of lupus-like syst