Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bettina Hartlieb"'
Autor:
Damir Fetahagic, Friedrich Scheiflinger, Bettina Hartlieb, Anita Kruzik, Maurus de la Rosa, Birgit M. Reipert, Herwig Koppensteiner, Frank M. Horling, Sebastian Dorn
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Preexisting immunity against adeno-associated virus (AAV) is a major challenge facing AAV gene therapy, resulting in the exclusion of patients from clinical trials. Accordingly, proper assessment of anti-AAV immunity is necessary for understanding cl
Autor:
Maurus de la Rosa, Stefan Romeder-Finger, Sogue Coulibaly, Sebastian Dorn, Frank M. Horling, Alfred Weber, Herwig Koppensteiner, Bettina Hartlieb, Birgit M. Reipert, Anita Kruzik, Friedrich Scheiflinger, Werner Hoellriegl, Damir Fetahagic
Publikováno v:
Human Gene Therapy Methods. 30:35-43
Patients with preexisting anti-adeno-associated virus serotype 8 (AAV8) neutralizing antibodies (NAbs) are currently excluded from AAV8 gene therapy trials. Therefore, the assessment of biologically relevant AAV8-NAb titers is critical for product de
Autor:
Anita, Kruzik, Herwig, Koppensteiner, Damir, Fetahagic, Bettina, Hartlieb, Sebastian, Dorn, Stefan, Romeder-Finger, Sogue, Coulibaly, Alfred, Weber, Werner, Hoellriegl, Frank M, Horling, Friedrich, Scheiflinger, Birgit M, Reipert, Maurus, de la Rosa
Publikováno v:
Human gene therapy methods. 30(2)
Patients with preexisting anti-adeno-associated virus serotype 8 (AAV8) neutralizing antibodies (NAbs) are currently excluded from AAV8 gene therapy trials. Therefore, the assessment of biologically relevant AAV8-NAb titers is critical for product de
Publikováno v:
Journal of Biological Chemistry. 288:11165-11174
Ebola virus is a non-segmented negative-sense RNA virus causing severe hemorrhagic fever with high fatality rates in humans and nonhuman primates. For transcription of the viral genome four viral proteins are essential: the nucleoprotein NP, the poly
Autor:
Heinrich G. Göttlinger, Charles Sabin, Bettina Hartlieb, Yoshiko Usami, Nolwenn Miguet, Sergiy V. Avilov, Winfried Weissenhorn, Nicolas Martinelli, Aurelien Dordor, Euripedes A. Ribeiro
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2012, 419 (1-2), pp.75-88
Journal of Molecular Biology, 2012, 419 (1-2), pp.75-88
Journal of Molecular Biology, Elsevier, 2012, 419 (1-2), pp.75-88
Journal of Molecular Biology, 2012, 419 (1-2), pp.75-88
International audience; Endosomal sorting complexes required for transport (ESCRTs) regulate diverse processes ranging from receptor sorting at endosomes to distinct steps in cell division and budding of some enveloped viruses. Common to all processe
Publikováno v:
Journal of Virology
Marburg virus infection is mediated by the only viral surface protein, GP, a trimeric type I transmembrane protein. While its ectodomain mediates receptor binding and fusion of viral and cellular membranes and its transmembrane domain is essential fo
Autor:
Olivier Reynard, Valentina A. Volchkova, Nathalie Alazard-Dany, Nadine Biedenkopf, Miguel J. Martínez, Viktor E. Volchkov, Bettina Hartlieb, Stephan Becker
Publikováno v:
Journal of Virology. 82:12569-12573
VP30 is a phosphoprotein essential for the initiation of Ebola virus transcription. In this work, we have studied the effect of mutations in VP30 phosphorylation sites on the ebolavirus replication cycle by using a reverse genetics system. We demonst
Autor:
Hideki Ebihara, Allison Groseth, Sandra Bamberg, Stephan Becker, Ute Ströher, Steven Theriault, Thomas Hoenen, Larissa Kolesnikova, Bettina Hartlieb, Heinz Feldmann
Publikováno v:
Journal of Virology. 80:7260-7264
Infectious virus-like particle (iVLP) systems have recently been established for several negative-strand RNA viruses, including the highly pathogenic Zaire ebolavirus (ZEBOV), and allow study of the viral life cycle under biosafety level 2 conditions
Autor:
David Lutje Hulsik, Bettina Hartlieb, Pauline Macheboeuf, Yoshiko Usami, Charles Sabin, Winfried Weissenhorn, Julianna Solomons, Heinrich G. Göttlinger, Emilie Poudevigne
Publikováno v:
Structure (London, England : 1993)
Structure (London, England : 1993), 2011, 19 (8), pp.1149-59
Structure (London, England : 1993), 2011, 19 (8), pp.1149-59
International audience; Endosomal sorting complexes required for transport (ESCRT) recognize ubiquitinated cargo and catalyze diverse budding processes including multivesicular body biogenesis, enveloped virus egress, and cytokinesis. We present the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5b6dbb8b4083813b0797d58341b843
https://hal.univ-grenoble-alpes.fr/hal-01243652
https://hal.univ-grenoble-alpes.fr/hal-01243652
Autor:
Yoshiko Usami, Ganesh Natrajan, Jean-Pierre Simorre, Heinrich G. Göttlinger, Andrew A. McCarthy, Nolwenn Miguet, Bettina Hartlieb, Patricia Renesto, Winfried Weissenhorn, Andreas Hinz, Hikaru Yamanaka
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
Cell Host and Microbe, Elsevier, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
Cell Host and Microbe, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
Cell Host and Microbe, Elsevier, 2010, 7 (4), pp.314-323. ⟨10.1016/j.chom.2010.03.005⟩
SummaryThe restriction factor BST-2/tetherin contains two membrane anchors employed to retain some enveloped viruses, including HIV-1 tethered to the plasma membrane in the absence of virus-encoded antagonists. The 2.77 Å crystal structure of the BS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2653e1995574b5a58d3b978338ad05ee
https://hal.science/hal-02107142
https://hal.science/hal-02107142