Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bettina H. Clausen"'
Autor:
Marius Piepke, Bettina H. Clausen, Peter Ludewig, Jonas H. Vienhues, Tanja Bedke, Ehsan Javidi, Björn Rissiek, Larissa Jank, Leonie Brockmann, Inga Sandrock, Karoline Degenhardt, Alina Jander, Vanessa Roth, Ines S. Schädlich, Immo Prinz, Richard A. Flavell, Yasushi Kobayashi, Thomas Renné, Christian Gerloff, Samuel Huber, Tim Magnus, Mathias Gelderblom
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Lymphocytes have dichotomous functions in ischemic stroke. Regulatory T cells are protective, while IL-17A from innate lymphocytes promotes the infarct growth. With recent advances of T cell-subtype specific transgenic mouse model
Externí odkaz:
https://doaj.org/article/84eccf40e2484f5c8eb8bfa924fd98ed
Autor:
Bettina H. Clausen, Martin Wirenfeldt, Sofie S. Høgedal, Lars H. Frich, Helle H. Nielsen, Henrik D. Schrøder, Kamilla Østergaard, Bente Finsen, Bjarne W. Kristensen, Kate L. Lambertsen
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Preclinical and clinical proof-of-concept studies have suggested the effectiveness of pharmacological modulation of inflammatory cytokines in ischemic stroke. Experimental evidence shows that targeting tumor necrosis factor (TNF) and interle
Externí odkaz:
https://doaj.org/article/3cae400332a44bbd9ebeeae911cf0139
Autor:
Helle H. Nielsen, Catarina B. Soares, Sofie S. Høgedal, Jonna S. Madsen, Rikke B. Hansen, Alex A. Christensen, Charlotte Madsen, Bettina H. Clausen, Lars Henrik Frich, Matilda Degn, Christian Sibbersen, Kate L. Lambertsen
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Ischemic stroke causes increased blood–brain barrier permeability and release of markers of axonal damage and inflammation. To investigate diagnostic and prognostic roles of neurofilament light chain (NF-L), we assessed levels of NF-L,
Externí odkaz:
https://doaj.org/article/80ab9067054241c3bf407ae0d6aabc2d
Autor:
Mathias Gelderblom, Simon Koch, Jan-Kolja Strecker, Carina Jørgensen, Lidia Garcia-Bonilla, Peter Ludewig, Ines Sophie Schädlich, Marius Piepke, Karoline Degenhardt, Christian Bernreuther, Hans Pinnschmidt, Thiruma V Arumugam, Götz Thomalla, Cornelius Faber, Jan Sedlacik, Christian Gerloff, Jens Minnerup, Bettina H Clausen, Josef Anrather, Tim Magnus
Publikováno v:
Brain Communications. 5
Multiple consensus statements have called for preclinical randomized controlled trials to improve translation in stroke research. We investigated the efficacy of an interleukin-17A neutralizing antibody in a multi-centre preclinical randomized contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3274721238f19fc1f4586cb4265b3e60
https://doi.org/10.1093/braincomms/fcad090
https://doi.org/10.1093/braincomms/fcad090
Autor:
Nane Griem-Krey, Anders B Klein, Bettina H Clausen, Mathias RJ Namini, Pernille V Nielsen, Mozammel Bhuiyan, Raghavendra Y Nagaraja, T Michael De Silva, Christopher G Sobey, Heung-Chin Cheng, Cyrille Orset, Denis Vivien, Kate L Lambertsen, Andrew N Clarkson, Petrine Wellendorph
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. :0271678X2311679
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a major contributor to physiological and pathological glutamate-mediated Ca2+ signals, and its involvement in various critical cellular pathways demands specific pharmacological strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8637415832d5febf3ea0d5559e757251
https://doi.org/10.1177/0271678x231167920
https://doi.org/10.1177/0271678x231167920
Autor:
Nane Griem-Krey, Anders B Klein, Bettina H Clausen, Mathias RJ Namini, Pernille V Nielsen, Heung-Chin Cheng, Cyrille Orset, Denis Vivien, Andrew N Clarkson, Kate L Lambertsen, Petrine Wellendorph
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a major contributor to physiological and pathological glutamate-mediated Ca2+ signals, and its involvement in various critical cellular pathways demands specific pharmacological strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15cc0e433be3fae36ba6aafb98fceb36
https://doi.org/10.1101/2022.03.10.483849
https://doi.org/10.1101/2022.03.10.483849
Autor:
Manuela, Grebing, Helle H, Nielsen, Christina D, Fenger, Katrine, T Jensen, Christian U, von Linstow, Bettina H, Clausen, Martin, Söderman, Kate L, Lambertsen, Mads, Thomassen, Torben A, Kruse, Bente, Finsen
Publikováno v:
Glia. 64(3)
Infiltration of myelin-specific T cells into the central nervous system induces the expression of proinflammatory cytokines in patients with multiple sclerosis (MS). We have previously shown that myelin-specific T cells are recruited into zones of ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db66da45199ed8f5e49f4e8bb1af5994
https://pubmed.ncbi.nlm.nih.gov/26496662
https://pubmed.ncbi.nlm.nih.gov/26496662